Sfoglia per Autore MACCHIA, BRUNO
3-(4-iodomethyl-2-oxo-1-azetidinyl)propynoic acid t-butyl ester: A new ß-lactam derivative. Synthesis of an ynamide by reaction of 4-iodomethylazetidin-2-one with the t-butyl ester of propiolic acid in the presence of copper (I)
1985-01-01 Balsamo, Aldo; Macchia, Bruno; F. MACCHIA E. P., Domiano; Rossello, Armando
SYNTHESIS AND EVALUATION OF THE PHARMACOLOGICAL ACTIVITY OF RIGID ANALOGS OF SYMPATHOMIMETIC CATECHOLAMINES DERIVED FROM BICYCLO[2.2.1]HEPTANE
1989-01-01 Balsamo, Aldo; Breschi, MARIA CRISTINA; Lapucci, Annalina; Macchia, Bruno; Macchia, F; Martinotti, E; Nencetti, Susanna; Nieri, Paola; Orlandini, Elisabetta
Conformationally restrained beta-blocking oxime ethers: synthesis and beta-adrenergic properties of diastereoisomeric anti and syn 2-(5-isoxazolidinyl)ethanolamines
1992-01-01 Balsamo, A; Breschi, M. C.; Chini, M; Domiano, P; Giannaccini, Gino; Lucacchini, Antonio; Macchia, Bruno; Macchia, Marco; Manera, Clementina
CONFORMATIONAL EFFECTS ON THE ACTIVITY OF DRUGS .13. A REVISION OF PREVIOUSLY PROPOSED MODELS FOR THE ACTIVATION OF ALPHA-ADRENERGIC AND BETA-ADRENERGIC RECEPTORS
1992-01-01 Macchia, Bruno; Balsamo, A; Breschi, MARIA CRISTINA; Lapucci, Annalina; Lucacchini, Antonio; Macchia, F; Manera, Clementina; Martinelli, Adriano; Martini, Claudia; Martinotti, E; Nencetti, Susanna
The [(Methyloxy)imino]methyl Moiety as a Bioisoster of Aryl. A Novel Class of Completely Aliphatic Beta-Adrenergic Receptor Antagonists
1994-01-01 Macchia, Bruno; Balsamo, Aldo; Breschi, MARIA CRISTINA; Chiellini, Grazia; Macchia, Marco; Martinelli, Adriano; Martini, Claudia; Nardini, C; Nencetti, Susanna; Rossello, Armando; Scatizzi, R.
Role of the benzylic hydroxyl group of adrenergic cattecholamines in eliciting alpha-adrenergic activity. Synthesis and alpha1- and alpha2-adrenergic activity of 3-phenyl-3-piperidinols and of their desoxy analogs
1995-01-01 Macchia, Bruno; Macchia, Marco; Manera, Clementina; Martinotti, E.
Synthesis and alpha-adrenergic activity of 2- and 6-methyl-substituted (3,4-dihydroxyphenyl)-3-piperidinols
1997-01-01 Macchia, Bruno; Macchia, Marco; Martinelli, A.; Martinotti, E.
N-n-Propyl-Substituted 3-(Dimethylphenyl)piperidines Display Novel Discriminative Properties between Dopamine Receptor Subtypes: Synthesis and Receptor Binding Studies
1998-01-01 Macchia, Bruno; Cervetto, L.; Demontis, GIAN CARLO ALFREDO GIUSEPPE; Longoni, B.
Synthesis and dopaminergic properties of the two enantiomers of 3-(3,4-dimethylphenyl)-1-propylpiperidine, a potent and selective dopamine D4 receptor ligand
2001-01-01 Macchia, Bruno; Cervetto, Luigi; Demontis, GIAN CARLO ALFREDO GIUSEPPE; Domiano, P; Longoni, Biancamaria; Macchia, Marco; Minutolo, Filippo; Orlandini, Elisabetta; Ortore, GABRIELLA MARIA PIA; Papi, C.
Spirotetrahydronaphthalene analogues of sympathomimetic catecholamines. Synthesis and adrenergic activity of 5,6- and 6,7-dihydroxy-3,4-dihydrospiro(naphtalen-1(2H)-3'-piperidines)
2002-01-01 Macchia, Bruno; Manera, Clementina; Martinelli, Adriano; Nencetti, Susanna; Orlandini, Elisabetta; Breschi, MARIA CRISTINA; Martini, Claudia; Martinotti, E.
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