Sfoglia per Autore
H2S-RELEASING PROPERTIES OF NEW THIOAMIDE, IMINOTHIOETHER AND ISOTHIOCYANATE DERIVATIVES
2012-01-01 Calderone, Vincenzo; Martelli, Alma; Testai, Lara; Marino, Alice; Pugliesi, I; Taliani, Sabrina; Nesi, Giulia; Rapposelli, Simona; DA SETTIMO PASSETTI, Federico; Breschi, MARIA CRISTINA
THIOAMIDE, IMINOTHIOETHER AND ISOTHIOCYANATE DERIVATIVES: CHEMOTYPES OF SLOW H2S-RELEASING AGENTS
2012-01-01 Martelli, Alma; Testai, Lara; Marino, Alice; Pugliesi, I; Taliani, Sabrina; Nesi, Giulia; Rapposelli, Simona; DA SETTIMO PASSETTI, Federico; Citi, Valentina; Breschi, MARIA CRISTINA; Calderone, Vincenzo
Targeting the upregulated PI3K-PDK1-Akt pathway: a drug discovery approach of treating cancer.
2012-01-01 Nesi, Giulia; Danesi, Romano; Lapucci, Annalina; Ricciardi, S; Sestito, Simona; Rapposelli, Simona
Synthesis and biological evaluation of (Hetero)aryl-methyloxyphenyl derivatives as potent P-glycoprotein modulating agents.
2013-01-01 Nesi, Giulia; Colabufo, N. A.; Contino, M.; Perrone, M. G.; Digiacomo, Maria; Perrone, R.; Lapucci, Annalina; Macchia, Marco; Rapposelli, Simona
Arylthioamides as H2S Donors:l-Cysteine-Activated Releasing Properties and Vascular Effects in Vitro and in Vivo
2013-01-01 Martelli, Alma; Testai, Lara; Citi, Valentina; Marino, Alice; Pugliesi, Isabella; Barresi, Elisabetta; Nesi, Giulia; Rapposelli, Simona; Taliani, Sabrina; DA SETTIMO PASSETTI, Federico; Breschi, MARIA CRISTINA; Calderone, Vincenzo
Synthesis of Novel 3,5-Disubstituted-2-oxindole Derivatives As Antitumor Agents against Human Nonsmall Cell Lung Cancer
2013-01-01 Nesi, Giulia; Sestito, Simona; Mey, V.; Ricciardi, S.; Falasca, M.; Danesi, Romano; Lapucci, Annalina; Breschi, MARIA CRISTINA; Fogli, Stefano; Rapposelli, Simona
SAR study on arylmethyloxyphenyl scaffold: Looking for a P-gp nanomolar affinity
2014-01-01 Nesi, Giulia; Colabufo, N. A.; Contino, M.; Perrone, M. G.; Digiacomo, Maria; Perrone, R.; Lapucci, Annalina; Macchia, Marco; Rapposelli, Simona
Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells
2015-01-01 Daniele, Simona; Costa, Barbara; Zappelli, Elisa; DA POZZO, Eleonora; Sestito, Simona; Nesi, Giulia; Campiglia, Pietro; Marinelli, Luciana; Novellino, Ettore; Rapposelli, Simona; Martini, Claudia
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme
2015-01-01 Sestito, Simona; Nesi, Giulia; Daniele, Simona; Martelli, Alma; Digiacomo, Maria; Borghini, Alice; Pietra, Daniele; Calderone, Vincenzo; Lapucci, Annalina; Falasca, Marco; Parrella, Paola; Notarangelo, Angelantonio; Breschi, MARIA CRISTINA; Macchia, Marco; Martini, Claudia; Rapposelli, Simona
Design, Synthesis, and Evaluation of Thyronamine Analogues as Novel Potent Mouse Trace Amine Associated Receptor 1 (m TAAR1) Agonists
2015-01-01 Chiellini, Grazia; Nesi, Giulia; Digiacomo, Maria; Malvasi, Rossella; Espinoza, Stefano; Sabatini, Martina; Frascarelli, Sabina; Laurino, Annunziatina; Cichero, Elena; Macchia, Marco; Gainetdinov, Raul R.; Fossa, Paola; Raimondi, Laura; Zucchi, Riccardo; Rapposelli, Simona
Symbiotic approach applied to the synthesis of new agents for the treatment of Alzheimer’s disease
2016-01-01 Nesi, Giulia; Shengnan, Wang; Sestito, Simona; Chiara, Barbieri; Ziwei, Chen; Xiaohong, Yang; Rongbiao, Pi; Rapposelli, Simona
Iminothioethers As A Novel Class Of H2s-Donor: Gasotransmitter Release And Vascular Effects
2016-01-01 Barresi, Elisabetta; Robello, Marco; Taliani, Sabrina; DA SETTIMO PASSETTI, Federico; Martelli, Alma; Testai, Lara; Citi, Valentina; Piragine, Eugenia; Rapposelli, Simona; Nesi, Giulia; Piano, Ilaria; Breschi, MARIA CRISTINA; Calderone, Vincenzo
Synthesis and In Vivo Imaging of N-(3-[11C]Methoxybenzyl)-2-(3-Methoxyphenyl)ethylaniline as a Potential Targeting Agent for P-glycoprotein
2016-01-01 Petroni, Debora; Bartoli, Antonietta; Rapposelli, Simona; Digiacomo, Maria; Burchielli, Silvia; Nesi, Giulia; Lapucci, Annalina; Pardini, Silvia; Fucci, Sabrina; Macchia, Marco; Salvadori, Piero A.; Menichetti, Luca
Hit-to-lead optimization of mouse Trace Amine Associated Receptor 1 (mTAAR1) agonists with a diphenylmethane-scaffold: Design, Synthesis, and biological study.
2016-01-01 Chiellini, Grazia; Nesi, Giulia; Sestito, Simona; Chiarugi, S; Runfola, M; Espinoza, S; Sabatini, Martina; Bellusci, L; Laurino, A; Cichero, E; Gainetdinov, Rr; Fossa, P; Raimondi, L; Zucchi, Riccardo; Rapposelli, Simona
Locking PDK1 in DFG-out conformation through 2-oxo-indole containing molecules: Another tools to fight glioblastoma
2016-01-01 Sestito, Simona; Daniele, Simona; Nesi, Giulia; Zappelli, Elisa; Di Maio, D; Marinelli, L; Digiacomo, Maria; Lapucci, Annalina; Martini, Claudia; Novellino, E; Rapposelli, Simona
Iminothioethers as a novel class of H2S-donor: gasotransmitter release and vascular effects
2017-01-01 Barresi, E.; Taliani, S.; Da Settimo, F.; Martelli, A.; Testai, L.; Citi, V.; Piragine, E.; Rapposelli, S.; Nesi, G.; Piano, I.; Gargini, M.; Breschi, M. C.; Calderone, V.
Endogenous TH metabolite 3-iodothyronamine (T1AM) and synthetic thyronamine-like analogues SG-1 and SG-2 induce autophagy in human glioblastoma cells (U-87MG)
2017-01-01 Bellusci, Lorenza; Martina, Sabatini; Nesi, Giulia; Rapposelli, Simona; Rossi, Leonardo; Lenzi, Paola; Fornai, Francesco; Zucchi, Riccardo; Chiellini, Grazia
Synthesis and functional evaluation of novel aldose reductase inhibitors bearing a spirobenzopyran scaffold
2017-01-01 Digiacomo, Maria; Sartini, Stefania; Nesi, Giulia; Sestito, Simona; Coviello, Vito; La Motta, Concettina; Rapposelli, Simona
Nature-based molecules combined with rivastigmine: A symbiotic approach for the synthesis of new agents against Alzheimer's disease
2017-01-01 Nesi, G; Chen, Q; Sestito, S; Digiacomo, M; Yang, X; Wang, S; Pi, R; Rapposelli, S.
Synthesis and Biological Evaluation of Cyclopropylamine Vitamin D‐Like CYP24A1 Inhibitors
2017-01-01 Chiellini, G.; Rapposelli, S.; Nesi, G.; Sestito, S.; Sabatini, M.; Zhu, J.; Massarelli, I.; Plum, L. A.; Clagett‐dame, M.; Deluca, H. F.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| H2S-RELEASING PROPERTIES OF NEW THIOAMIDE, IMINOTHIOETHER AND ISOTHIOCYANATE DERIVATIVES | 1-gen-2012 | Calderone, Vincenzo; Martelli, Alma; Testai, Lara; Marino, Alice; Pugliesi, I; Taliani, Sabrina; Nesi, Giulia; Rapposelli, Simona; DA SETTIMO PASSETTI, Federico; Breschi, MARIA CRISTINA | |
| THIOAMIDE, IMINOTHIOETHER AND ISOTHIOCYANATE DERIVATIVES: CHEMOTYPES OF SLOW H2S-RELEASING AGENTS | 1-gen-2012 | Martelli, Alma; Testai, Lara; Marino, Alice; Pugliesi, I; Taliani, Sabrina; Nesi, Giulia; Rapposelli, Simona; DA SETTIMO PASSETTI, Federico; Citi, Valentina; Breschi, MARIA CRISTINA; Calderone, Vincenzo | |
| Targeting the upregulated PI3K-PDK1-Akt pathway: a drug discovery approach of treating cancer. | 1-gen-2012 | Nesi, Giulia; Danesi, Romano; Lapucci, Annalina; Ricciardi, S; Sestito, Simona; Rapposelli, Simona | |
| Synthesis and biological evaluation of (Hetero)aryl-methyloxyphenyl derivatives as potent P-glycoprotein modulating agents. | 1-gen-2013 | Nesi, Giulia; Colabufo, N. A.; Contino, M.; Perrone, M. G.; Digiacomo, Maria; Perrone, R.; Lapucci, Annalina; Macchia, Marco; Rapposelli, Simona | |
| Arylthioamides as H2S Donors:l-Cysteine-Activated Releasing Properties and Vascular Effects in Vitro and in Vivo | 1-gen-2013 | Martelli, Alma; Testai, Lara; Citi, Valentina; Marino, Alice; Pugliesi, Isabella; Barresi, Elisabetta; Nesi, Giulia; Rapposelli, Simona; Taliani, Sabrina; DA SETTIMO PASSETTI, Federico; Breschi, MARIA CRISTINA; Calderone, Vincenzo | |
| Synthesis of Novel 3,5-Disubstituted-2-oxindole Derivatives As Antitumor Agents against Human Nonsmall Cell Lung Cancer | 1-gen-2013 | Nesi, Giulia; Sestito, Simona; Mey, V.; Ricciardi, S.; Falasca, M.; Danesi, Romano; Lapucci, Annalina; Breschi, MARIA CRISTINA; Fogli, Stefano; Rapposelli, Simona | |
| SAR study on arylmethyloxyphenyl scaffold: Looking for a P-gp nanomolar affinity | 1-gen-2014 | Nesi, Giulia; Colabufo, N. A.; Contino, M.; Perrone, M. G.; Digiacomo, Maria; Perrone, R.; Lapucci, Annalina; Macchia, Marco; Rapposelli, Simona | |
| Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells | 1-gen-2015 | Daniele, Simona; Costa, Barbara; Zappelli, Elisa; DA POZZO, Eleonora; Sestito, Simona; Nesi, Giulia; Campiglia, Pietro; Marinelli, Luciana; Novellino, Ettore; Rapposelli, Simona; Martini, Claudia | |
| Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme | 1-gen-2015 | Sestito, Simona; Nesi, Giulia; Daniele, Simona; Martelli, Alma; Digiacomo, Maria; Borghini, Alice; Pietra, Daniele; Calderone, Vincenzo; Lapucci, Annalina; Falasca, Marco; Parrella, Paola; Notarangelo, Angelantonio; Breschi, MARIA CRISTINA; Macchia, Marco; Martini, Claudia; Rapposelli, Simona | |
| Design, Synthesis, and Evaluation of Thyronamine Analogues as Novel Potent Mouse Trace Amine Associated Receptor 1 (m TAAR1) Agonists | 1-gen-2015 | Chiellini, Grazia; Nesi, Giulia; Digiacomo, Maria; Malvasi, Rossella; Espinoza, Stefano; Sabatini, Martina; Frascarelli, Sabina; Laurino, Annunziatina; Cichero, Elena; Macchia, Marco; Gainetdinov, Raul R.; Fossa, Paola; Raimondi, Laura; Zucchi, Riccardo; Rapposelli, Simona | |
| Symbiotic approach applied to the synthesis of new agents for the treatment of Alzheimer’s disease | 1-gen-2016 | Nesi, Giulia; Shengnan, Wang; Sestito, Simona; Chiara, Barbieri; Ziwei, Chen; Xiaohong, Yang; Rongbiao, Pi; Rapposelli, Simona | |
| Iminothioethers As A Novel Class Of H2s-Donor: Gasotransmitter Release And Vascular Effects | 1-gen-2016 | Barresi, Elisabetta; Robello, Marco; Taliani, Sabrina; DA SETTIMO PASSETTI, Federico; Martelli, Alma; Testai, Lara; Citi, Valentina; Piragine, Eugenia; Rapposelli, Simona; Nesi, Giulia; Piano, Ilaria; Breschi, MARIA CRISTINA; Calderone, Vincenzo | |
| Synthesis and In Vivo Imaging of N-(3-[11C]Methoxybenzyl)-2-(3-Methoxyphenyl)ethylaniline as a Potential Targeting Agent for P-glycoprotein | 1-gen-2016 | Petroni, Debora; Bartoli, Antonietta; Rapposelli, Simona; Digiacomo, Maria; Burchielli, Silvia; Nesi, Giulia; Lapucci, Annalina; Pardini, Silvia; Fucci, Sabrina; Macchia, Marco; Salvadori, Piero A.; Menichetti, Luca | |
| Hit-to-lead optimization of mouse Trace Amine Associated Receptor 1 (mTAAR1) agonists with a diphenylmethane-scaffold: Design, Synthesis, and biological study. | 1-gen-2016 | Chiellini, Grazia; Nesi, Giulia; Sestito, Simona; Chiarugi, S; Runfola, M; Espinoza, S; Sabatini, Martina; Bellusci, L; Laurino, A; Cichero, E; Gainetdinov, Rr; Fossa, P; Raimondi, L; Zucchi, Riccardo; Rapposelli, Simona | |
| Locking PDK1 in DFG-out conformation through 2-oxo-indole containing molecules: Another tools to fight glioblastoma | 1-gen-2016 | Sestito, Simona; Daniele, Simona; Nesi, Giulia; Zappelli, Elisa; Di Maio, D; Marinelli, L; Digiacomo, Maria; Lapucci, Annalina; Martini, Claudia; Novellino, E; Rapposelli, Simona | |
| Iminothioethers as a novel class of H2S-donor: gasotransmitter release and vascular effects | 1-gen-2017 | Barresi, E.; Taliani, S.; Da Settimo, F.; Martelli, A.; Testai, L.; Citi, V.; Piragine, E.; Rapposelli, S.; Nesi, G.; Piano, I.; Gargini, M.; Breschi, M. C.; Calderone, V. | |
| Endogenous TH metabolite 3-iodothyronamine (T1AM) and synthetic thyronamine-like analogues SG-1 and SG-2 induce autophagy in human glioblastoma cells (U-87MG) | 1-gen-2017 | Bellusci, Lorenza; Martina, Sabatini; Nesi, Giulia; Rapposelli, Simona; Rossi, Leonardo; Lenzi, Paola; Fornai, Francesco; Zucchi, Riccardo; Chiellini, Grazia | |
| Synthesis and functional evaluation of novel aldose reductase inhibitors bearing a spirobenzopyran scaffold | 1-gen-2017 | Digiacomo, Maria; Sartini, Stefania; Nesi, Giulia; Sestito, Simona; Coviello, Vito; La Motta, Concettina; Rapposelli, Simona | |
| Nature-based molecules combined with rivastigmine: A symbiotic approach for the synthesis of new agents against Alzheimer's disease | 1-gen-2017 | Nesi, G; Chen, Q; Sestito, S; Digiacomo, M; Yang, X; Wang, S; Pi, R; Rapposelli, S. | |
| Synthesis and Biological Evaluation of Cyclopropylamine Vitamin D‐Like CYP24A1 Inhibitors | 1-gen-2017 | Chiellini, G.; Rapposelli, S.; Nesi, G.; Sestito, S.; Sabatini, M.; Zhu, J.; Massarelli, I.; Plum, L. A.; Clagett‐dame, M.; Deluca, H. F. |
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