X-Linked hypophosphataemic rickets (XLH) is frequently associated with short stature even when conventional treatment (1,25-dihydroxyvitamin D-3 or 1 alpha-hydroxyvitamin D-3 plus inorganic phosphate salts) is administered for a long time. The pathogenesis of growth retardation is probably multifactorial. Affected patients usually show normal growth hormone (GH) secretion. in some poorly growing XLH patients, long-term GH treatment associated with conventional therapy improves linear growth. GH treatment also increases phosphate retention but th is effect is transient. Copyright (C) 2000 S. Karger AG, Basel.

Hypophosphataemic rickets

SAGGESE, GIUSEPPE;
2000-01-01

Abstract

X-Linked hypophosphataemic rickets (XLH) is frequently associated with short stature even when conventional treatment (1,25-dihydroxyvitamin D-3 or 1 alpha-hydroxyvitamin D-3 plus inorganic phosphate salts) is administered for a long time. The pathogenesis of growth retardation is probably multifactorial. Affected patients usually show normal growth hormone (GH) secretion. in some poorly growing XLH patients, long-term GH treatment associated with conventional therapy improves linear growth. GH treatment also increases phosphate retention but th is effect is transient. Copyright (C) 2000 S. Karger AG, Basel.
2000
Saggese, Giuseppe; Baroncelli, Gi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/161106
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