In a group of girls with Turner's syndrome we evaluated the effect of the administration of pirenzepine, an anticholinergic substance, on GH secretion in response to L-Dopa and insulin-tolerance test. Our results demonstrated that pirenzepine was able to block GH release, showing an involvement of the cholinergic mechanism in GH secretion regulation in subjects with Turner's syndrome.
Anticholinergic drugs administration inhibits growth-hormone secretion in response to provocative stimuli tests in girls with Turners Syndrome
SAGGESE, GIUSEPPE;
1991-01-01
Abstract
In a group of girls with Turner's syndrome we evaluated the effect of the administration of pirenzepine, an anticholinergic substance, on GH secretion in response to L-Dopa and insulin-tolerance test. Our results demonstrated that pirenzepine was able to block GH release, showing an involvement of the cholinergic mechanism in GH secretion regulation in subjects with Turner's syndrome.File in questo prodotto:
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