A simple, efficient method is described for the synthesis of γ-hydroxy ketones by the direct opening of 1,2-epoxides with lithium enolates derived from simple ketones in anhydrous toluene, in the presence of Y(OTf)3. Reaxys Database Information |
YTTRIUM TRIFLATE-CATALYZED ADDITION OF LITHIUM ENOLATES TO 1,2-EPOXIDES - EFFICIENT SYNTHESIS OF GAMMA-HYDROXY KETONES
CROTTI, PAOLO;DI BUSSOLO, VALERIA;FAVERO, LUCILLA;PINESCHI, MAURO
1994-01-01
Abstract
A simple, efficient method is described for the synthesis of γ-hydroxy ketones by the direct opening of 1,2-epoxides with lithium enolates derived from simple ketones in anhydrous toluene, in the presence of Y(OTf)3. Reaxys Database Information |File in questo prodotto:
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