We are assembling a high resolution small animal PET scanner. The detector module is composed of a YAP:Ce matrix, consisting of 400 crystals 2 x 2 x 30 mm(3) glued together, and optically isolated by a 5 mu m thick reflective layer. The matrix is directly coupled to a position sensitive photomultiplier Hamamatsu mod. R2486-06 (PSPMT). Two detector modules are mounted on a rotating gantry. The opposite detectors can be positioned at a distance ranging from 5 to 25 cm so that the scanner transaxial FOV (Fiel Of View) is variable in the 2.5-15 cm range. The scanner axial FOV is 4 cm. The positron test source was Na-22. The system will operate in 3D data acquisition mode. The measured axial spatial resolution at the center using a simple back-projection planar reconstruction algorithm is 2.3 mm FWHM after correction for the PSPMT position nonlinearities and for source dimension. By eliminating the full-absorption events (mainly due to multiple interactions in the multi-crystals) the spatial resolution was improved to 1.8 mm. This result is very appropriate for small animal PET studies. (C) 1998 Elsevier Science B.V. All rights reserved.

High spatial resolution small animal YAP-PET

DEL GUERRA, ALBERTO;
1998-01-01

Abstract

We are assembling a high resolution small animal PET scanner. The detector module is composed of a YAP:Ce matrix, consisting of 400 crystals 2 x 2 x 30 mm(3) glued together, and optically isolated by a 5 mu m thick reflective layer. The matrix is directly coupled to a position sensitive photomultiplier Hamamatsu mod. R2486-06 (PSPMT). Two detector modules are mounted on a rotating gantry. The opposite detectors can be positioned at a distance ranging from 5 to 25 cm so that the scanner transaxial FOV (Fiel Of View) is variable in the 2.5-15 cm range. The scanner axial FOV is 4 cm. The positron test source was Na-22. The system will operate in 3D data acquisition mode. The measured axial spatial resolution at the center using a simple back-projection planar reconstruction algorithm is 2.3 mm FWHM after correction for the PSPMT position nonlinearities and for source dimension. By eliminating the full-absorption events (mainly due to multiple interactions in the multi-crystals) the spatial resolution was improved to 1.8 mm. This result is very appropriate for small animal PET studies. (C) 1998 Elsevier Science B.V. All rights reserved.
1998
DEL GUERRA, Alberto; Di Domenico, G; Scandola, M; Zavattini, G.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/44150
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