The quality of general movements (GMs) and its predictive value have never been evaluated in late-preterm (LP) infants.To determine the characteristics of GMs and their predictive value for neurodevelopmental outcome in a cohort of infants born between 34 and 36 weeks' gestation.574 LP infants were examined using the standard methodological principles of Prechtl's method for assessing GMs both during writhing and fidgety periods.Infants were assessed at 2 years of age with neuromotor and developmental scales.A significant correlation was found between GMs and outcome both at writhing (rs 0.68; p < 0.001) and at fidgety age (rs 0.78; p < 0.001). The assessment at 1 month showed 100\% sensitivity and 86\% specificity of predicting the development of cerebral palsy (CP), that at 3 months was 100\% sensitivity and 97\% specificity.During the fidgety age GMs predict CP with very high sensitivity and specificity. The qualitative assessment of GMs should be employed to help identify LP infants who require early intervention for neurological abnormalities.
Prognostic value of the qualitative assessments of general movements in late-preterm infants.
GUZZETTA, ANDREA
2013-01-01
Abstract
The quality of general movements (GMs) and its predictive value have never been evaluated in late-preterm (LP) infants.To determine the characteristics of GMs and their predictive value for neurodevelopmental outcome in a cohort of infants born between 34 and 36 weeks' gestation.574 LP infants were examined using the standard methodological principles of Prechtl's method for assessing GMs both during writhing and fidgety periods.Infants were assessed at 2 years of age with neuromotor and developmental scales.A significant correlation was found between GMs and outcome both at writhing (rs 0.68; p < 0.001) and at fidgety age (rs 0.78; p < 0.001). The assessment at 1 month showed 100\% sensitivity and 86\% specificity of predicting the development of cerebral palsy (CP), that at 3 months was 100\% sensitivity and 97\% specificity.During the fidgety age GMs predict CP with very high sensitivity and specificity. The qualitative assessment of GMs should be employed to help identify LP infants who require early intervention for neurological abnormalities.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.