Six patients with Steinert disease were treated with selenium and vitamin E, for a 24 month period, including a first phase of 12 months, 6 months wash-out interval and a second treatment phase of 6 months. Mean segmental strength values showed significant improvement during the first 12 months of therapy, while marked reductions of serum enzymes CPK, SGOT, SGPT and gamma-GT were observed in some patients. The results support the hypothesis that selenium may play a role in the development of muscle damage in Steinert disease.
Effects of selenium and vitamin E on muscular strength and blood parameters in Steinert disease.
ROSSI, BRUNO;SICILIANO, GABRIELE;
1990-01-01
Abstract
Six patients with Steinert disease were treated with selenium and vitamin E, for a 24 month period, including a first phase of 12 months, 6 months wash-out interval and a second treatment phase of 6 months. Mean segmental strength values showed significant improvement during the first 12 months of therapy, while marked reductions of serum enzymes CPK, SGOT, SGPT and gamma-GT were observed in some patients. The results support the hypothesis that selenium may play a role in the development of muscle damage in Steinert disease.File in questo prodotto:
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