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ARPI, l'Archivio della Ricerca dell'Universita di Pisa, raccoglie le pubblicazioni e la documentazione sui prodotti della ricerca scientifica del personale dell'ateneo. L'archivio e gestito da IRIS, il sistema di gestione integrata dei dati della ricerca del CINECA.
Per informazioni, contattare arpi@unipi.it

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Improving preclinical cancer models: lessons from human and canine clinical trials of metronomic chemotherapy

Based on results from the past ten years, this ready reference systematically describes how to prepare, carry out, and evaluate animal studies for cancer therapies, addressing the widely recognized lack of reliable and reproducible results. Following a short historical introduction an...

Metronomic chemotherapy for triple negative breast cancer?

Breast cancer risk varies widely and increases with age. Despite the incidence for women older than 70 years being 33%, they are usually excluded from screening schedules and clinical trials. Furthermore, about 15% of breast cancers in older patients are of the triple-negative subt...

Exposure of the IMA made easy

[No abstract available]

Therapeutic management of hypothenar hammer syndrome causing ulnar nerve entrapment

Introduction. The hypothenar hammer syndrome is a rare traumatic vascular disease of the hand. Method and Materials. We report the case of a 43-years-old man with a painful tumefaction of the left hypothenar region. The ulnar artery appeared thrombosed clinically and radiologically. The...

CD133 and ABCB5 as stem cell markers on sentinel lymph node from melanoma patients

CD133 is one of most studied marker of stemness expressed by melanoma cells. ABCB5 is specifically expressed on CD133þ tumor stem cell phenotype indicating that ABCB5þ/CD133þ cells may represent the melanoma stem cells fraction. Nevertheless, there is disagreement concerning the constant...

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