CINECA IRIS Institutional Research Information System

IRIS è la soluzione IT che facilita la raccolta e la gestione dei dati relativi alle attività e ai prodotti della ricerca. Fornisce a ricercatori, amministratori e valutatori gli strumenti per monitorare i risultati della ricerca, aumentarne la visibilità e allocare in modo efficace le risorse disponibili.

ARPI, l'Archivio della Ricerca dell'Università di Pisa, raccoglie le pubblicazioni e la documentazione sui prodotti della ricerca scientifica del personale dell'ateneo. L'archivio è gestito da IRIS, il sistema di gestione integrata dei dati della ricerca del CINECA.
Per informazioni, contattare arpi@unipi.it

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Multidisciplinary study of a new ClC-1 mutation causing myotonia congenita: a paradigm to understand and treat ion channelopathies

Myotonia congenita is an inherited disease that is characterized by impaired muscle relaxation after contraction caused by loss-of-function mutations in the skeletal muscle ClC-1 channel. We report a novel ClC-1 mutation, T335N, that is associated with a mild phenotype in 1 patient, loc...

The long sedimentary succession of the valle giumentina basin (abruzzo, central italy): New evidence from stratigraphic studies and electrical resistivity tomography (ert)

We carried out a multidisciplinary study on the sedimentary succession of Valle Giumentina, a small intermountain basin located in the Central Apennine. Studied in the 1950s, this 70 m-thick succession, including nine Palaeolithic occupation layers, was considered to be of Rissian and W...

Quantitative expression and co-localization of Wnt signalling related proteins in feline squamous cell carcinoma

Feline oral squamous cell carcinoma (FOSCC) is an aggressive neoplasm in cats. Little is known about the possible molecular mechanisms that may be involved in the initiation, maintenance and progression of FOSCC. Wnt signalling is critical in development and disease, including many mamm...

The Acheulian and early Middle Paleolithic in Latium (Italy): Stability and innovation

We present here the results of a technological and typological analysis of the Acheulian and early Middle Paleolithic assemblages from Torre in Pietra (Latium, Italy) together with comparisons with the Acheulian small tools of Castel di Guido. The assemblages were never chronometrically ...

The clinical use of statistical permutation test methodology: a tool for identifying predictive variables of outcome

To identify the predictive variables affecting the outcome after radical surgery for bladder cancer by a newer statistical methodology, i.e. nonparametric combination (NPC). METHODS: A multicenter study enrolled 1,312 patients who had undergone radical cystectomy for bladder cancer in 11 Italian&...