MARCHETTI, PIERO Statistiche
MARCHETTI, PIERO
DIPARTIMENTO DI MEDICINA CLINICA E SPERIMENTALE
A long non-coding RNA that harbors a SNP associated with type 2 diabetes regulates the expression of TGM2 gene in pancreatic beta cells
2023-01-01 González-Moro, Itziar; Rojas-Márquez, Henar; Sebastian-delaCruz, Maialen; Mentxaka-Salgado, Jon; Olazagoitia-Garmendia, Ane; Mendoza, Luis Manuel; Lluch, Aina; Fantuzzi, Federica; Lambert, Carmen; Ares Blanco, Jessica; Marselli, Lorella; Marchetti, Piero; Cnop, Miriam; Delgado, Elías; Fernández-Real, José Manuel; Ortega, Francisco José; Castellanos-Rubio, Ainara; Santin, Izortze
A long non-coding RNA that harbors a SNP associated with type 2 diabetes regulates the expression of TGM2 gene in pancreatic beta cells
2023-01-01 González-Moro, Itziar; Rojas-Márquez, Henar; Sebastian-delaCruz, Maialen; Mentxaka-Salgado, Jon; Olazagoitia-Garmendia, Ane; Mendoza, Luis Manuel; Lluch, Aina; Fantuzzi, Federica; Lambert, Carmen; Ares Blanco, Jessica; Marselli, Lorella; Marchetti, Piero; Cnop, Miriam; Delgado, Elías; Fernández-Real, José Manuel; Ortega, Francisco José; Castellanos-Rubio, Ainara; Santin, Izortze
GLP-1R agonists demonstrate potential to treat Wolfram syndrome in human preclinical models
2023-01-01 Gorgogietas, Vyron; Rajaei, Bahareh; Heeyoung, Chae; Santacreu, Bruno J; Marín-Cañas, Sandra; Salpea, Paraskevi; Sawatani, Toshiaki; Musuaya, Anyishai; Arroyo, María N; Moreno-Castro, Cristina; Benabdallah, Khadija; Demarez, Celine; Toivonen, Sanna; Cosentino, Cristina; Pachera, Nathalie; Lytrivi, Maria; Cai, Ying; Carnel, Lode; Brown, Cris; Urano, Fumihiko; Marchetti, Piero; Gilon, Patrick; Eizirik, Decio L; Cnop, Miriam; Igoillo-Esteve, Mariana
Inhibition of the type 1 diabetes candidate gene PTPN2 aggravates TNF-α-induced human beta cell dysfunction and death
2023-01-01 Roca-Rivada, Arturo; Marín-Cañas, Sandra; Colli, Maikel L; Vinci, Chiara; Sawatani, Toshiaki; Marselli, Lorella; Cnop, Miriam; Marchetti, Piero; Eizirik, Decio L
The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes
2023-01-01 Huerta-Chagoya, Alicia; Schroeder, Philip; Mandla, Ravi; Deutsch, Aaron J; Zhu, Wanying; Petty, Lauren; Yi, Xiaoyan; Cole, Joanne B; Udler, Miriam S; Dornbos, Peter; Porneala, Bianca; Dicorpo, Daniel; Liu, Ching-Ti; Li, Josephine H; Szczerbiński, Lukasz; Kaur, Varinderpal; Kim, Joohyun; Lu, Yingchang; Martin, Alicia; Eizirik, Decio L; Marchetti, Piero; Marselli, Lorella; Chen, Ling; Srinivasan, Shylaja; Todd, Jennifer; Flannick, Jason; Gubitosi-Klug, Rose; Levitsky, Lynne; Shah, Rachana; Kelsey, Megan; Burke, Brian; Dabelea, Dana M; Divers, Jasmin; Marcovina, Santica; Stalbow, Lauren; Loos, Ruth J F; Darst, Burcu F; Kooperberg, Charles; Raffield, Laura M; Haiman, Christopher; Sun, Quan; Mccormick, Joseph B; Fisher-Hoch, Susan P; Ordoñez, Maria L; Meigs, James; Baier, Leslie J; González-Villalpando, Clicerio; González-Villalpando, Maria Elena; Orozco, Lorena; García-García, Lourdes; Moreno-Estrada, Andrés; Aguilar-Salinas, Carlos A; Tusié, Teresa; Dupuis, Josée; Ng, Maggie C Y; Manning, Alisa; Highland, Heather M; Cnop, Miriam; Hanson, Robert; Below, Jennifer; Florez, Jose C; Leong, Aaron; Mercader, Josep M
A single-cell human islet interactome atlas identifies disrupted autocrine and paracrine communications in type 2 diabetes
2022-01-01 Bosi, Emanuele; Marselli, Lorella; Suleiman, Mara; Tesi, Marta; De Luca, Carmela; Del Guerra, Silvia; Cnop, Miriam; Eizirik, Decio L; Marchetti, Piero
ADAR1-dependent editing regulates human β cell transcriptome diversity during inflammation
2022-01-01 Szymczak, Florian; Cohen-Fultheim, Roni; Thomaidou, Sofia; de Brachène, Alexandra Coomans; Castela, Angela; Colli, Maikel; Marchetti, Piero; Levanon, Erez; Eizirik, Decio; Zaldumbide, Arnaud
Every islet matters: improving the impact of human islet research
2022-01-01 Gloyn, Anna L; Ibberson, Mark; Marchetti, Piero; Powers, Alvin C; Rorsman, Patrik; Sander, Maike; Solimena, Michele
Glucose-Dependent miR-125b Is a Negative Regulator of β-Cell Function
2022-01-01 Cheung, Rebecca; Pizza, Grazia; Chabosseau, Pauline; Rolando, Delphine; Tomas, Alejandra; Burgoyne, Thomas; Wu, Zhiyi; Salowka, Anna; Thapa, Anusha; Macklin, Annabel; Cao, Yufei; Nguyen-Tu, Marie-Sophie; Dickerson, Matthew T; Jacobson, David A; Marchetti, Piero; Shapiro, James; Piemonti, Lorenzo; de Koning, Eelco; Leclerc, Isabelle; Bouzakri, Karim; Sakamoto, Kei; Smith, David M; Rutter, Guy A; Martinez-Sanchez, Aida
Human alpha cell transcriptomic signatures of types 1 and 2 diabetes highlight disease-specific dysfunction pathways
2022-01-01 Bosi, Emanuele; Marchetti, Piero; Rutter, Guy Allen; Eizirik, Decio Laks
In depth functional characterization of human induced pluripotent stem cell-derived beta cells in vitro and in vivo
2022-01-01 Fantuzzi, Federica; Toivonen, Sanna; Schiavo, Andrea Alex; Chae, Heeyoung; Tariq, Mohammad; Sawatani, Toshiaki; Pachera, Nathalie; Cai, Ying; Vinci, Chiara; Virgilio, Enrico; Ladriere, Laurence; Suleiman, Mara; Marchetti, Piero; Jonas, Jean-Christophe; Gilon, Patrick; Eizirik, Décio L; Igoillo-Esteve, Mariana; Cnop, Miriam
In vivo and in vitro characterization of GL0034, a novel long-acting glucagon-like peptide-1 receptor agonist
2022-01-01 Jones, Ben; Burade, Vinod; Akalestou, Elina; Manchanda, Yusman; Ramchunder, Zenouska; Carrat, Gaëlle; Nguyen-Tu, Marie-Sophie; Marchetti, Piero; Piemonti, Lorenzo; Leclerc, Isabelle; Thennati, Rajamannar; Vilsboll, Tina; Thorens, Bernard; Tomas, Alejandra; Rutter, Guy A
Increased Expression of Viral Sensor MDA5 in Pancreatic Islets and in Hormone-Negative Endocrine Cells in Recent Onset Type 1 Diabetic Donors
2022-01-01 Nigi, Laura; Brusco, Noemi; Grieco, Giuseppina E; Fignani, Daniela; Licata, Giada; Formichi, Caterina; Aiello, Elena; Marselli, Lorella; Marchetti, Piero; Krogvold, Lars; Jorgensen, Knut Dahl; Sebastiani, Guido; Dotta, Francesco
Islet Gene View-a tool to facilitate islet research
2022-01-01 Asplund, Olof; Storm, Petter; Chandra, Vikash; Hatem, Gad; Ottosson-Laakso, Emilia; Mansour-Aly, Dina; Krus, Ulrika; Ibrahim, Hazem; Ahlqvist, Emma; Tuomi, Tiinamaija; Renström, Erik; Korsgren, Olle; Wierup, Nils; Ibberson, Mark; Solimena, Michele; Marchetti, Piero; Wollheim, Claes; Artner, Isabella; Mulder, Hindrik; Hansson, Ola; Otonkoski, Timo; Groop, Leif; Prasad, Rashmi B
Mining the transcriptome of target tissues of autoimmune and degenerative pancreatic β-cell and brain diseases to discover therapies
2022-01-01 Yi, Xiaoyan; Marmontel de Souza, Bianca; Sawatani, Toshiaki; Szymczak, Florian; Marselli, Lorella; Marchetti, Piero; Cnop, Miriam; Eizirik, Decio L
Protective effects of Stevia rebaudiana extracts on beta cells in lipotoxic conditions
2022-01-01 Bugliani, Marco; Tavarini, Silvia; Grano, Francesca; Tondi, Silvia; Lacerenza, Serena; Giusti, Laura; Ronci, Maurizio; Maidecchi, Anna; Marchetti, Piero; Tesi, Marta; Angelini, Luciana G.
Reduced miR-184-3p expression protects pancreatic β-cells from lipotoxic and proinflammatory apoptosis in type 2 diabetes via CRTC1 upregulation
2022-01-01 Grieco, Giuseppina E; Brusco, Noemi; Fignani, Daniela; Nigi, Laura; Formichi, Caterina; Licata, Giada; Marselli, Lorella; Marchetti, Piero; Salvini, Laura; Tinti, Laura; Po, Agnese; Ferretti, Elisabetta; Sebastiani, Guido; Dotta, Francesco
Single-cell imaging of α and β cell metabolic response to glucose in living human Langerhans islets
2022-01-01 Azzarello, Fabio; Pesce, Luca; De Lorenzi, Valentina; Ferri, Gianmarco; Tesi, Marta; Del Guerra, Silvia; Marchetti, Piero; Cardarelli, Francesco
The p66Shc Protein Mediates Insulin Resistance and Secretory Dysfunction in Pancreatic β-Cells Under Lipotoxic Conditions
2022-01-01 Biondi, Giuseppina; Marrano, Nicola; Dipaola, Lucia; Borrelli, Anna; Rella, Martina; D'Oria, Rossella; Genchi, Valentina A; Caccioppoli, Cristina; Porreca, Immacolata; Cignarelli, Angelo; Perrini, Sebastio; Marchetti, Piero; Vincenti, Leonardo; Laviola, Luigi; Giorgino, Francesco; Natalicchio, Annalisa
The Protective Action of Metformin against Pro-Inflammatory Cytokine-Induced Human Islet Cell Damage and the Mechanisms Involved
2022-01-01 Giusti, Laura; Tesi, Marta; Ciregia, Federica; Marselli, Lorella; Zallocco, Lorenzo; Suleiman, Mara; De Luca, Carmela; Del Guerra, Silvia; Zuccarini, Mariachiara; Trerotola, Marco; Eizirik, Decio L; Cnop, Miriam; Mazzoni, Maria R; Marchetti, Piero; Lucacchini, Antonio; Ronci, Maurizio
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A long non-coding RNA that harbors a SNP associated with type 2 diabetes regulates the expression of TGM2 gene in pancreatic beta cells | 1-gen-2023 | González-Moro, Itziar; Rojas-Márquez, Henar; Sebastian-delaCruz, Maialen; Mentxaka-Salgado, Jon; Olazagoitia-Garmendia, Ane; Mendoza, Luis Manuel; Lluch, Aina; Fantuzzi, Federica; Lambert, Carmen; Ares Blanco, Jessica; Marselli, Lorella; Marchetti, Piero; Cnop, Miriam; Delgado, Elías; Fernández-Real, José Manuel; Ortega, Francisco José; Castellanos-Rubio, Ainara; Santin, Izortze | |
| A long non-coding RNA that harbors a SNP associated with type 2 diabetes regulates the expression of TGM2 gene in pancreatic beta cells | 1-gen-2023 | González-Moro, Itziar; Rojas-Márquez, Henar; Sebastian-delaCruz, Maialen; Mentxaka-Salgado, Jon; Olazagoitia-Garmendia, Ane; Mendoza, Luis Manuel; Lluch, Aina; Fantuzzi, Federica; Lambert, Carmen; Ares Blanco, Jessica; Marselli, Lorella; Marchetti, Piero; Cnop, Miriam; Delgado, Elías; Fernández-Real, José Manuel; Ortega, Francisco José; Castellanos-Rubio, Ainara; Santin, Izortze | |
| GLP-1R agonists demonstrate potential to treat Wolfram syndrome in human preclinical models | 1-gen-2023 | Gorgogietas, Vyron; Rajaei, Bahareh; Heeyoung, Chae; Santacreu, Bruno J; Marín-Cañas, Sandra; Salpea, Paraskevi; Sawatani, Toshiaki; Musuaya, Anyishai; Arroyo, María N; Moreno-Castro, Cristina; Benabdallah, Khadija; Demarez, Celine; Toivonen, Sanna; Cosentino, Cristina; Pachera, Nathalie; Lytrivi, Maria; Cai, Ying; Carnel, Lode; Brown, Cris; Urano, Fumihiko; Marchetti, Piero; Gilon, Patrick; Eizirik, Decio L; Cnop, Miriam; Igoillo-Esteve, Mariana | |
| Inhibition of the type 1 diabetes candidate gene PTPN2 aggravates TNF-α-induced human beta cell dysfunction and death | 1-gen-2023 | Roca-Rivada, Arturo; Marín-Cañas, Sandra; Colli, Maikel L; Vinci, Chiara; Sawatani, Toshiaki; Marselli, Lorella; Cnop, Miriam; Marchetti, Piero; Eizirik, Decio L | |
| The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes | 1-gen-2023 | Huerta-Chagoya, Alicia; Schroeder, Philip; Mandla, Ravi; Deutsch, Aaron J; Zhu, Wanying; Petty, Lauren; Yi, Xiaoyan; Cole, Joanne B; Udler, Miriam S; Dornbos, Peter; Porneala, Bianca; Dicorpo, Daniel; Liu, Ching-Ti; Li, Josephine H; Szczerbiński, Lukasz; Kaur, Varinderpal; Kim, Joohyun; Lu, Yingchang; Martin, Alicia; Eizirik, Decio L; Marchetti, Piero; Marselli, Lorella; Chen, Ling; Srinivasan, Shylaja; Todd, Jennifer; Flannick, Jason; Gubitosi-Klug, Rose; Levitsky, Lynne; Shah, Rachana; Kelsey, Megan; Burke, Brian; Dabelea, Dana M; Divers, Jasmin; Marcovina, Santica; Stalbow, Lauren; Loos, Ruth J F; Darst, Burcu F; Kooperberg, Charles; Raffield, Laura M; Haiman, Christopher; Sun, Quan; Mccormick, Joseph B; Fisher-Hoch, Susan P; Ordoñez, Maria L; Meigs, James; Baier, Leslie J; González-Villalpando, Clicerio; González-Villalpando, Maria Elena; Orozco, Lorena; García-García, Lourdes; Moreno-Estrada, Andrés; Aguilar-Salinas, Carlos A; Tusié, Teresa; Dupuis, Josée; Ng, Maggie C Y; Manning, Alisa; Highland, Heather M; Cnop, Miriam; Hanson, Robert; Below, Jennifer; Florez, Jose C; Leong, Aaron; Mercader, Josep M | |
| A single-cell human islet interactome atlas identifies disrupted autocrine and paracrine communications in type 2 diabetes | 1-gen-2022 | Bosi, Emanuele; Marselli, Lorella; Suleiman, Mara; Tesi, Marta; De Luca, Carmela; Del Guerra, Silvia; Cnop, Miriam; Eizirik, Decio L; Marchetti, Piero | |
| ADAR1-dependent editing regulates human β cell transcriptome diversity during inflammation | 1-gen-2022 | Szymczak, Florian; Cohen-Fultheim, Roni; Thomaidou, Sofia; de Brachène, Alexandra Coomans; Castela, Angela; Colli, Maikel; Marchetti, Piero; Levanon, Erez; Eizirik, Decio; Zaldumbide, Arnaud | |
| Every islet matters: improving the impact of human islet research | 1-gen-2022 | Gloyn, Anna L; Ibberson, Mark; Marchetti, Piero; Powers, Alvin C; Rorsman, Patrik; Sander, Maike; Solimena, Michele | |
| Glucose-Dependent miR-125b Is a Negative Regulator of β-Cell Function | 1-gen-2022 | Cheung, Rebecca; Pizza, Grazia; Chabosseau, Pauline; Rolando, Delphine; Tomas, Alejandra; Burgoyne, Thomas; Wu, Zhiyi; Salowka, Anna; Thapa, Anusha; Macklin, Annabel; Cao, Yufei; Nguyen-Tu, Marie-Sophie; Dickerson, Matthew T; Jacobson, David A; Marchetti, Piero; Shapiro, James; Piemonti, Lorenzo; de Koning, Eelco; Leclerc, Isabelle; Bouzakri, Karim; Sakamoto, Kei; Smith, David M; Rutter, Guy A; Martinez-Sanchez, Aida | |
| Human alpha cell transcriptomic signatures of types 1 and 2 diabetes highlight disease-specific dysfunction pathways | 1-gen-2022 | Bosi, Emanuele; Marchetti, Piero; Rutter, Guy Allen; Eizirik, Decio Laks | |
| In depth functional characterization of human induced pluripotent stem cell-derived beta cells in vitro and in vivo | 1-gen-2022 | Fantuzzi, Federica; Toivonen, Sanna; Schiavo, Andrea Alex; Chae, Heeyoung; Tariq, Mohammad; Sawatani, Toshiaki; Pachera, Nathalie; Cai, Ying; Vinci, Chiara; Virgilio, Enrico; Ladriere, Laurence; Suleiman, Mara; Marchetti, Piero; Jonas, Jean-Christophe; Gilon, Patrick; Eizirik, Décio L; Igoillo-Esteve, Mariana; Cnop, Miriam | |
| In vivo and in vitro characterization of GL0034, a novel long-acting glucagon-like peptide-1 receptor agonist | 1-gen-2022 | Jones, Ben; Burade, Vinod; Akalestou, Elina; Manchanda, Yusman; Ramchunder, Zenouska; Carrat, Gaëlle; Nguyen-Tu, Marie-Sophie; Marchetti, Piero; Piemonti, Lorenzo; Leclerc, Isabelle; Thennati, Rajamannar; Vilsboll, Tina; Thorens, Bernard; Tomas, Alejandra; Rutter, Guy A | |
| Increased Expression of Viral Sensor MDA5 in Pancreatic Islets and in Hormone-Negative Endocrine Cells in Recent Onset Type 1 Diabetic Donors | 1-gen-2022 | Nigi, Laura; Brusco, Noemi; Grieco, Giuseppina E; Fignani, Daniela; Licata, Giada; Formichi, Caterina; Aiello, Elena; Marselli, Lorella; Marchetti, Piero; Krogvold, Lars; Jorgensen, Knut Dahl; Sebastiani, Guido; Dotta, Francesco | |
| Islet Gene View-a tool to facilitate islet research | 1-gen-2022 | Asplund, Olof; Storm, Petter; Chandra, Vikash; Hatem, Gad; Ottosson-Laakso, Emilia; Mansour-Aly, Dina; Krus, Ulrika; Ibrahim, Hazem; Ahlqvist, Emma; Tuomi, Tiinamaija; Renström, Erik; Korsgren, Olle; Wierup, Nils; Ibberson, Mark; Solimena, Michele; Marchetti, Piero; Wollheim, Claes; Artner, Isabella; Mulder, Hindrik; Hansson, Ola; Otonkoski, Timo; Groop, Leif; Prasad, Rashmi B | |
| Mining the transcriptome of target tissues of autoimmune and degenerative pancreatic β-cell and brain diseases to discover therapies | 1-gen-2022 | Yi, Xiaoyan; Marmontel de Souza, Bianca; Sawatani, Toshiaki; Szymczak, Florian; Marselli, Lorella; Marchetti, Piero; Cnop, Miriam; Eizirik, Decio L | |
| Protective effects of Stevia rebaudiana extracts on beta cells in lipotoxic conditions | 1-gen-2022 | Bugliani, Marco; Tavarini, Silvia; Grano, Francesca; Tondi, Silvia; Lacerenza, Serena; Giusti, Laura; Ronci, Maurizio; Maidecchi, Anna; Marchetti, Piero; Tesi, Marta; Angelini, Luciana G. | |
| Reduced miR-184-3p expression protects pancreatic β-cells from lipotoxic and proinflammatory apoptosis in type 2 diabetes via CRTC1 upregulation | 1-gen-2022 | Grieco, Giuseppina E; Brusco, Noemi; Fignani, Daniela; Nigi, Laura; Formichi, Caterina; Licata, Giada; Marselli, Lorella; Marchetti, Piero; Salvini, Laura; Tinti, Laura; Po, Agnese; Ferretti, Elisabetta; Sebastiani, Guido; Dotta, Francesco | |
| Single-cell imaging of α and β cell metabolic response to glucose in living human Langerhans islets | 1-gen-2022 | Azzarello, Fabio; Pesce, Luca; De Lorenzi, Valentina; Ferri, Gianmarco; Tesi, Marta; Del Guerra, Silvia; Marchetti, Piero; Cardarelli, Francesco | |
| The p66Shc Protein Mediates Insulin Resistance and Secretory Dysfunction in Pancreatic β-Cells Under Lipotoxic Conditions | 1-gen-2022 | Biondi, Giuseppina; Marrano, Nicola; Dipaola, Lucia; Borrelli, Anna; Rella, Martina; D'Oria, Rossella; Genchi, Valentina A; Caccioppoli, Cristina; Porreca, Immacolata; Cignarelli, Angelo; Perrini, Sebastio; Marchetti, Piero; Vincenti, Leonardo; Laviola, Luigi; Giorgino, Francesco; Natalicchio, Annalisa | |
| The Protective Action of Metformin against Pro-Inflammatory Cytokine-Induced Human Islet Cell Damage and the Mechanisms Involved | 1-gen-2022 | Giusti, Laura; Tesi, Marta; Ciregia, Federica; Marselli, Lorella; Zallocco, Lorenzo; Suleiman, Mara; De Luca, Carmela; Del Guerra, Silvia; Zuccarini, Mariachiara; Trerotola, Marco; Eizirik, Decio L; Cnop, Miriam; Mazzoni, Maria R; Marchetti, Piero; Lucacchini, Antonio; Ronci, Maurizio |