POLI, GIULIO Statistiche
POLI, GIULIO
DIPARTIMENTO DI FARMACIA
Hybridization Approach Applied to Umbelliferon and Vanilloids toward New Inhibitors of Carbonic Anhydrases IX and XII with In Vitro Antiproliferative and Anti-inflammatory Activities
2026-01-01 Melfi, Francesco; Mencarelli, Noemi; Carradori, Simone; Gallorini, Marialucia; Angeli, Andrea; Poli, Giulio; Cataldi, Amelia; D'Agostino, Ilaria; Di Credico, Andrea; Di Baldassarre, Angela; Tuccinardi, Tiziano; Supuran, Claudiu T
Machine Learning-Based Virtual Screening for the Identification of Novel CDK-9 Inhibitors
2026-01-01 Piazza, Lisa; Poles, Clarissa; Bononi, Giulia; Granchi, Carlotta; Di Stefano, Miriana; Poli, Giulio; Giordano, Antonio; Medugno, Annamaria; Napolitano, Giuseppe Maria; Tuccinardi, Tiziano; Alfano, Luigi
Novel Insights on Benzo[b]thiophene Analogues for MAO-B Inhibition and Neuroprotection: Design, Synthesis, Molecular Modelling Studies and Biological Activity
2026-01-01 Arrighi, Francesca; Berrino, Emanuela; Guglielmi, Paolo; Carradori, Simone; Marconi, Guya Diletta; Pizzicannella, Jacopo; Guarnieri, Simone; Tuccinardi, Tiziano; Poli, Giulio; Pepi, Federico; Troiani, Anna; Salvitti, Chiara; Di Noi, Alessia; Coluccia, Michele; Buttitta, Giorgio; Pontecorvi, Virginia; Granese, Arianna; Chimenti, Paola; Secci, Daniela; Petzer, Anel; Petzer, Jacobus Petrus; Diomede, Francesca
Structure-based design of new pyrazole inhibitors targeting Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH)
2026-01-01 Pippione, Agnese C; Villella, Noemi; Fornaseri, Federico; Giorgis, Marta; Sharma, Manmohan; Rolando, Barbara; Sainas, Stefano; Salamanca, Efrain; Gimenez, Alberto; Cojean, Sandrine; Vyas, Vivek K; Buccinnà, Barbara; Ramondetti, Cristina; Piccinini, Marco; Poli, Giulio; Tuccinardi, Tiziano; Alberti, Marta; Miggiano, Riccardo; Lolli, Marco L; Boschi, Donatella
A Machine Learning Platform for Isoform-Specific Identification and Profiling of Human Carbonic Anhydrase Inhibitors
2025-01-01 Piazza, Lisa; Di Stefano, Miriana; Poles, Clarissa; Bononi, Giulia; Poli, Giulio; Renzi, Gioele; Galati, Salvatore; Giordano, Antonio; Macchia, Marco; Carta, Fabrizio; Supuran, Claudiu T; Tuccinardi, Tiziano
A series of benzensulfonamide derivatives as new potent carbonic anhydrase IX and XII inhibitors
2025-01-01 Nencetti, Susanna; Cuffaro, Doretta; Ciccone, Lidia; Nocentini, Alessio; Di Stefano, Miriana; Poli, Giulio; Macchia, Marco; Tuccinardi, Tiziano; Nuti, Elisa; Supuran, Claudiu T.; Rossello, Armando; Orlandini, Elisabetta
ADvisor: An Open-Source Tool for Applicability Domain Definition and Optimization in Molecular Predictive Modeling
2025-01-01 Piazza, Lisa; Poles, Clarissa; Bononi, Giulia; Granchi, Carlotta; Di Stefano, Miriana; Poli, Giulio; Macchia, Marco; Tuccinardi, Tiziano
ConPath 2.0: an optimized consensus strategy for assessing the potential pathogenicity of hRPE65 missense variants
2025-01-01 Poli, Giulio; Galati, Salvatore; Macchia, Marco; Tuccinardi, Tiziano
Identification of a Non-Retinoid Opsin Ligand Through Pharmacophore-Guided Virtual Screening-A Novel Potential Rhodopsin-Stabilizing Compound
2025-01-01 Di Stefano, Miriana; Ghilardi, Maria; Poles, Clarissa; Piazza, Lisa; Demontis, Gian Carlo; Poli, Giulio; Tuccinardi, Tiziano; Macchia, Marco
KinasePred: A Computational Tool for Small-Molecule Kinase Target Prediction
2025-01-01 Di Stefano, Miriana; Piazza, Lisa; Poles, Clarissa; Galati, Salvatore; Granchi, Carlotta; Giordano, Antonio; Campisi, Luca; Macchia, Marco; Poli, Giulio; Tuccinardi, Tiziano
ProSECFPs: A Novel Fingerprint-Based Protein Representation Method for Missense Mutation Pathogenicity Prediction
2025-01-01 Poles, Clarissa; Di Stefano, Miriana; Piazza, Lisa; Bononi, Giulia; Poli, Giulio; Macchia, Marco; Tuccinardi, Tiziano; Giordano, Antonio
Structure-based analysis of missense mutations impacting the catalytic and substrate binding sites of hRPE65
2025-01-01 Poli, Giulio; Macchia, Marco; Tuccinardi, Tiziano
A comprehensive review of synthetic strategies and SAR studies for the discovery of PfDHODH inhibitors as antimalarial agents. Part 1: triazolopyrimidine, isoxazolopyrimidine and pyrrole-based (DSM) compounds
2024-01-01 Sharma, Manmohan; Pandey, Vinita; Poli, Giulio; Tuccinardi, Tiziano; Lolli, Marco L; Vyas, Vivek K
An alternative conformation of the N-terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent
2024-01-01 Alberti, Marta; Poli, Giulio; Broggini, Luca; Sainas, Stefano; Rizzi, Menico; Boschi, Donatella; Ferraris, Davide M; Martino, Elena; Ricagno, Stefano; Tuccinardi, Tiziano; Lolli, Marco L; Miggiano, Riccardo
An update on antibacterial AlkylGuanidino Ureas: Design of new derivatives, synergism with colistin and data analysis of the whole library
2024-01-01 Ardino, Claudia; Sannio, Filomena; Poli, Giulio; Galati, Salvatore; Dreassi, Elena; Botta, Lorenzo; Docquier, Jean-Denis; D'Agostino, Ilaria
Design, synthesis, ADME and biological evaluation of benzylpiperidine and benzylpiperazine derivatives as novel reversible monoacylglycerol lipase (MAGL) inhibitors
2024-01-01 Di Stefano, Miriana; Masoni, Samuele; Bononi, Giulia; Poli, Giulio; Galati, Salvatore; Gado, Francesca; Manzi, Simone; Vagaggini, Chiara; Brai, Annalaura; Caligiuri, Isabella; Asif, Kanwal; Rizzolio, Flavio; Macchia, Marco; Chicca, Andrea; Sodi, Andrea; Di Bussolo, Valeria; Minutolo, Filippo; Meier, Philip; Gertsch, Jürg; Granchi, Carlotta; Dreassi, Elena; Tuccinardi, Tiziano
Identification of Novel Non-Nucleoside Inhibitors of Zika Virus NS5 Protein Targeting MTase Activity
2024-01-01 Fiorucci, Diego; Meaccini, Micaela; Poli, Giulio; Stincarelli, Maria Alfreda; Vagaggini, Chiara; Giannecchini, Simone; Sutto-Ortiz, Priscila; Canard, Bruno; Decroly, Etienne; Dreassi, Elena; Brai, Annalaura; Botta, Maurizio
Nuovi agenti antivirali a struttura N-idrossiindrol-carbossamidica
2024-01-01 Minutolo, Filippo; Pistello, Mauro; DI BUSSOLO, Valeria; Freer, Giulia; Quaranta, Paola; Granchi, Carlotta; Tuccinardi, Tiziano; Poli, Giulio; Bononi, Giulia; Masoni, Samuele
Sirtuin 1-activating derivatives belonging to the anilinopyridine class displaying in vivo cardioprotective activities
2024-01-01 Bononi, G.; Citi, V.; Martelli, A.; Poli, G.; Tuccinardi, T.; Granchi, C.; Testai, L.; Calderone, V.; Minutolo, F.
SMS121, a new inhibitor of CD36, impairs fatty acid uptake and viability of acute myeloid leukemia
2024-01-01 Åbacka, Hannah; Masoni, Samuele; Poli, Giulio; Huang, Peng; Gusso, Francesco; Granchi, Carlotta; Minutolo, Filippo; Tuccinardi, Tiziano; Hagström-Andersson, Anna K; Lindkvist-Petersson, Karin
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Hybridization Approach Applied to Umbelliferon and Vanilloids toward New Inhibitors of Carbonic Anhydrases IX and XII with In Vitro Antiproliferative and Anti-inflammatory Activities | 1-gen-2026 | Melfi, Francesco; Mencarelli, Noemi; Carradori, Simone; Gallorini, Marialucia; Angeli, Andrea; Poli, Giulio; Cataldi, Amelia; D'Agostino, Ilaria; Di Credico, Andrea; Di Baldassarre, Angela; Tuccinardi, Tiziano; Supuran, Claudiu T | |
| Machine Learning-Based Virtual Screening for the Identification of Novel CDK-9 Inhibitors | 1-gen-2026 | Piazza, Lisa; Poles, Clarissa; Bononi, Giulia; Granchi, Carlotta; Di Stefano, Miriana; Poli, Giulio; Giordano, Antonio; Medugno, Annamaria; Napolitano, Giuseppe Maria; Tuccinardi, Tiziano; Alfano, Luigi | |
| Novel Insights on Benzo[b]thiophene Analogues for MAO-B Inhibition and Neuroprotection: Design, Synthesis, Molecular Modelling Studies and Biological Activity | 1-gen-2026 | Arrighi, Francesca; Berrino, Emanuela; Guglielmi, Paolo; Carradori, Simone; Marconi, Guya Diletta; Pizzicannella, Jacopo; Guarnieri, Simone; Tuccinardi, Tiziano; Poli, Giulio; Pepi, Federico; Troiani, Anna; Salvitti, Chiara; Di Noi, Alessia; Coluccia, Michele; Buttitta, Giorgio; Pontecorvi, Virginia; Granese, Arianna; Chimenti, Paola; Secci, Daniela; Petzer, Anel; Petzer, Jacobus Petrus; Diomede, Francesca | |
| Structure-based design of new pyrazole inhibitors targeting Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) | 1-gen-2026 | Pippione, Agnese C; Villella, Noemi; Fornaseri, Federico; Giorgis, Marta; Sharma, Manmohan; Rolando, Barbara; Sainas, Stefano; Salamanca, Efrain; Gimenez, Alberto; Cojean, Sandrine; Vyas, Vivek K; Buccinnà, Barbara; Ramondetti, Cristina; Piccinini, Marco; Poli, Giulio; Tuccinardi, Tiziano; Alberti, Marta; Miggiano, Riccardo; Lolli, Marco L; Boschi, Donatella | |
| A Machine Learning Platform for Isoform-Specific Identification and Profiling of Human Carbonic Anhydrase Inhibitors | 1-gen-2025 | Piazza, Lisa; Di Stefano, Miriana; Poles, Clarissa; Bononi, Giulia; Poli, Giulio; Renzi, Gioele; Galati, Salvatore; Giordano, Antonio; Macchia, Marco; Carta, Fabrizio; Supuran, Claudiu T; Tuccinardi, Tiziano | |
| A series of benzensulfonamide derivatives as new potent carbonic anhydrase IX and XII inhibitors | 1-gen-2025 | Nencetti, Susanna; Cuffaro, Doretta; Ciccone, Lidia; Nocentini, Alessio; Di Stefano, Miriana; Poli, Giulio; Macchia, Marco; Tuccinardi, Tiziano; Nuti, Elisa; Supuran, Claudiu T.; Rossello, Armando; Orlandini, Elisabetta | |
| ADvisor: An Open-Source Tool for Applicability Domain Definition and Optimization in Molecular Predictive Modeling | 1-gen-2025 | Piazza, Lisa; Poles, Clarissa; Bononi, Giulia; Granchi, Carlotta; Di Stefano, Miriana; Poli, Giulio; Macchia, Marco; Tuccinardi, Tiziano | |
| ConPath 2.0: an optimized consensus strategy for assessing the potential pathogenicity of hRPE65 missense variants | 1-gen-2025 | Poli, Giulio; Galati, Salvatore; Macchia, Marco; Tuccinardi, Tiziano | |
| Identification of a Non-Retinoid Opsin Ligand Through Pharmacophore-Guided Virtual Screening-A Novel Potential Rhodopsin-Stabilizing Compound | 1-gen-2025 | Di Stefano, Miriana; Ghilardi, Maria; Poles, Clarissa; Piazza, Lisa; Demontis, Gian Carlo; Poli, Giulio; Tuccinardi, Tiziano; Macchia, Marco | |
| KinasePred: A Computational Tool for Small-Molecule Kinase Target Prediction | 1-gen-2025 | Di Stefano, Miriana; Piazza, Lisa; Poles, Clarissa; Galati, Salvatore; Granchi, Carlotta; Giordano, Antonio; Campisi, Luca; Macchia, Marco; Poli, Giulio; Tuccinardi, Tiziano | |
| ProSECFPs: A Novel Fingerprint-Based Protein Representation Method for Missense Mutation Pathogenicity Prediction | 1-gen-2025 | Poles, Clarissa; Di Stefano, Miriana; Piazza, Lisa; Bononi, Giulia; Poli, Giulio; Macchia, Marco; Tuccinardi, Tiziano; Giordano, Antonio | |
| Structure-based analysis of missense mutations impacting the catalytic and substrate binding sites of hRPE65 | 1-gen-2025 | Poli, Giulio; Macchia, Marco; Tuccinardi, Tiziano | |
| A comprehensive review of synthetic strategies and SAR studies for the discovery of PfDHODH inhibitors as antimalarial agents. Part 1: triazolopyrimidine, isoxazolopyrimidine and pyrrole-based (DSM) compounds | 1-gen-2024 | Sharma, Manmohan; Pandey, Vinita; Poli, Giulio; Tuccinardi, Tiziano; Lolli, Marco L; Vyas, Vivek K | |
| An alternative conformation of the N-terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent | 1-gen-2024 | Alberti, Marta; Poli, Giulio; Broggini, Luca; Sainas, Stefano; Rizzi, Menico; Boschi, Donatella; Ferraris, Davide M; Martino, Elena; Ricagno, Stefano; Tuccinardi, Tiziano; Lolli, Marco L; Miggiano, Riccardo | |
| An update on antibacterial AlkylGuanidino Ureas: Design of new derivatives, synergism with colistin and data analysis of the whole library | 1-gen-2024 | Ardino, Claudia; Sannio, Filomena; Poli, Giulio; Galati, Salvatore; Dreassi, Elena; Botta, Lorenzo; Docquier, Jean-Denis; D'Agostino, Ilaria | |
| Design, synthesis, ADME and biological evaluation of benzylpiperidine and benzylpiperazine derivatives as novel reversible monoacylglycerol lipase (MAGL) inhibitors | 1-gen-2024 | Di Stefano, Miriana; Masoni, Samuele; Bononi, Giulia; Poli, Giulio; Galati, Salvatore; Gado, Francesca; Manzi, Simone; Vagaggini, Chiara; Brai, Annalaura; Caligiuri, Isabella; Asif, Kanwal; Rizzolio, Flavio; Macchia, Marco; Chicca, Andrea; Sodi, Andrea; Di Bussolo, Valeria; Minutolo, Filippo; Meier, Philip; Gertsch, Jürg; Granchi, Carlotta; Dreassi, Elena; Tuccinardi, Tiziano | |
| Identification of Novel Non-Nucleoside Inhibitors of Zika Virus NS5 Protein Targeting MTase Activity | 1-gen-2024 | Fiorucci, Diego; Meaccini, Micaela; Poli, Giulio; Stincarelli, Maria Alfreda; Vagaggini, Chiara; Giannecchini, Simone; Sutto-Ortiz, Priscila; Canard, Bruno; Decroly, Etienne; Dreassi, Elena; Brai, Annalaura; Botta, Maurizio | |
| Nuovi agenti antivirali a struttura N-idrossiindrol-carbossamidica | 1-gen-2024 | Minutolo, Filippo; Pistello, Mauro; DI BUSSOLO, Valeria; Freer, Giulia; Quaranta, Paola; Granchi, Carlotta; Tuccinardi, Tiziano; Poli, Giulio; Bononi, Giulia; Masoni, Samuele | |
| Sirtuin 1-activating derivatives belonging to the anilinopyridine class displaying in vivo cardioprotective activities | 1-gen-2024 | Bononi, G.; Citi, V.; Martelli, A.; Poli, G.; Tuccinardi, T.; Granchi, C.; Testai, L.; Calderone, V.; Minutolo, F. | |
| SMS121, a new inhibitor of CD36, impairs fatty acid uptake and viability of acute myeloid leukemia | 1-gen-2024 | Åbacka, Hannah; Masoni, Samuele; Poli, Giulio; Huang, Peng; Gusso, Francesco; Granchi, Carlotta; Minutolo, Filippo; Tuccinardi, Tiziano; Hagström-Andersson, Anna K; Lindkvist-Petersson, Karin |