TUCCINARDI, TIZIANO Statistiche
TUCCINARDI, TIZIANO
DIPARTIMENTO DI FARMACIA
Enhanced activity of a pluronic F127 formulated Pin1 inhibitor for ovarian cancer therapy
2023-01-01 Saorin, G.; Mauceri, M.; Cavarzerani, E.; Caligiuri, I.; Bononi, G.; Granchi, C.; Bartoletti, M.; Perin, T.; Tuccinardi, T.; Canzonieri, V.; Adeel, M.; Rizzolio, F.
A carrier free delivery system of a monoacylglycerol lipase hydrophobic inhibitor
2022-01-01 Adeel, Muhammad; Saorin, Gloria; Boccalon, Giacomo; Sfriso, Andrea Augusto; Parisi, Salvatore; Moro, Isabella; Palazzolo, Stefano; Caligiuri, Isabella; Granchi, Carlotta; Corona, Giuseppe; Cemazar, Maja; Canzonieri, Vincenzo; Tuccinardi, Tiziano; Rizzolio, Flavio
Co-Inhibition of P-gp and Hsp90 by an Isatin-Derived Compound Contributes to the Increase of the Chemosensitivity of MCF7/ADR-Resistant Cells to Doxorubicin
2022-01-01 Abdalla, Ashraf N; Di Stefano, Miriana; Poli, Giulio; Tuccinardi, Tiziano; Bader, Ammar; Vassallo, Antonio; Abdallah, Mohamed E; El-Readi, Mahmoud Zaki; Refaat, Bassem; Algarni, Alanood S; Ahmad, Rizwan; Alkahtani, Hamad M; Abdel-Aziz, Alaa A-M; El-Azab, Adel S; Alqathama, Aljawharah
Dissecting the Activity of Catechins as Incomplete Aldose Reductase Differential Inhibitors through Kinetic and Computational Approaches
2022-01-01 Balestri, Francesco; Poli, Giulio; Piazza, Lucia; Cappiello, Mario; Moschini, Roberta; Signore, Giovanni; Tuccinardi, Tiziano; Mura, Umberto; Del Corso, Antonella
Expansion of the 4-(Diethylamino)benzaldehyde Scaffold to Explore the Impact on Aldehyde Dehydrogenase Activity and Antiproliferative Activity in Prostate Cancer
2022-01-01 Ibrahim, Ali I M; Batlle, Elisabet; Sneha, Smarakan; Jiménez, Rafael; Pequerul, Raquel; Parés, Xavier; Rüngeler, Till; Jha, Vibhu; Tuccinardi, Tiziano; Sadiq, Maria; Frame, Fiona; Maitland, Norman J; Farrés, Jaume; Pors, Klaus
From Anti-infective Agents to Cancer Therapy: a Drug Repositioning Study Revealed a New Use for Nitrofuran Derivatives
2022-01-01 Ortore, Gabriella; Poli, Giulio; Martinelli, Adriano; Tuccinardi, Tiziano; Rizzolio, Flavio; Caligiuri, Isabella
Growth performances, chemical composition, and microbiological loads of mealworm reared with brewery spent grains and bread leftovers
2022-01-01 Mancini, S.; Fratini, F.; Provera, I.; Dovicchi, J.; Tuccinardi, T.; Minieri, S.; Papini, R. A.; Forzan, M.; Paci, G.
Historical perspective of tumor glycolysis: a century with Otto Warburg
2022-01-01 Bononi, Giulia; Masoni, Samuele; Di Bussolo, Valeria; Tuccinardi, Tiziano; Granchi, Carlotta; Minutolo, Filippo
Identification of Human Dihydroorotate Dehydrogenase Inhibitor by a Pharmacophore-Based Virtual Screening Study
2022-01-01 Galati, Salvatore; Sainas, Stefano; Giorgis, Marta; Boschi, Donatella; Lolli, Marco L; Ortore, Gabriella; Poli, Giulio; Tuccinardi, Tiziano
Machine Learning-Based Virtual Screening for the Identification of Cdk5 Inhibitors
2022-01-01 Di Stefano, Miriana; Galati, Salvatore; Ortore, Gabriella; Caligiuri, Isabella; Rizzolio, Flavio; Ceni, Costanza; Bertini, Simone; Bononi, Giulia; Granchi, Carlotta; Macchia, Marco; Poli, Giulio; Tuccinardi, Tiziano
New PIN1 inhibitors identified through a pharmacophore-driven, hierarchical consensus docking strategy
2022-01-01 Poli, Giulio; Di Stefano, Miriana; Estevez, Joan Arias; Minutolo, Filippo; Granchi, Carlotta; Giordano, Antonio; Parisi, Salvatore; Mauceri, Matteo; Canzonieri, Vincenzo; Macchia, Marco; Caligiuri, Isabella; Tuccinardi, Tiziano; Rizzolio, Flavio
New Synthetic Analogues of Natural Polyphenols as Sirtuin 1-Activating Compounds
2022-01-01 Bononi, G.; Flori, L.; Citi, V.; Acciai, C.; Nocilla, V.; Martelli, A.; Poli, G.; Tuccinardi, T.; Granchi, C.; Testai, L.; Calderone, V.; Minutolo, F.
Novel Potent and Selective Agonists of the GPR55 Receptor Based on the 3-Benzylquinolin-2(1H)-One Scaffold
2022-01-01 Ceni, Costanza; Benko, Michael J; Mohamed, Kawthar A; Poli, Giulio; Di Stefano, Miriana; Tuccinardi, Tiziano; Digiacomo, Maria; Valoti, Massimo; Laprairie, Robert B; Macchia, Marco; Bertini, Simone
Predicting potentially pathogenic effects of hRPE65 missense mutations: a computational strategy based on molecular dynamics simulations
2022-01-01 Poli, Giulio; Barravecchia, Ivana; Demontis, Gian Carlo; Sodi, Andrea; Saba, Alessandro; Rizzo, Stanislao; Macchia, Marco; Tuccinardi, Tiziano
Resveratrol Analogues as Dual Inhibitors of Monoamine Oxidase B and Carbonic Anhydrase VII: A New Multi-Target Combination for Neurodegenerative Diseases?
2022-01-01 Carradori, Simone; Fantacuzzi, Marialuigia; Ammazzalorso, Alessandra; Angeli, Andrea; De Filippis, Barbara; Galati, Salvatore; Petzer, Anél; Petzer, Jacobus P; Poli, Giulio; Tuccinardi, Tiziano; Agamennone, Mariangela; Supuran, Claudiu T
Reversible Monoacylglycerol Lipase Inhibitors: Discovery of a New Class of Benzylpiperidine Derivatives
2022-01-01 Bononi, Giulia; Di Stefano, Miriana; Poli, Giulio; Ortore, Gabriella; Meier, Philip; Masetto, Francesca; Caligiuri, Isabella; Rizzolio, Flavio; Macchia, Marco; Chicca, Andrea; Avan, Amir; Giovannetti, Elisa; Vagaggini, Chiara; Brai, Annalaura; Dreassi, Elena; Valoti, Massimo; Minutolo, Filippo; Granchi, Carlotta; Gertsch, Jürg; Tuccinardi, Tiziano
Sirtuin 1-Activating Compounds: Discovery of a Class of Thiazole-Based Derivatives
2022-01-01 Bononi, G.; Citi, V.; Lapillo, M.; Martelli, A.; Poli, G.; Tuccinardi, T.; Granchi, C.; Testai, L.; Calderone, V.; Minutolo, F.
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Aryloxyaryl Moiety
2022-01-01 Sainas, Stefano; Giorgis, Marta; Circosta, Paola; Poli, Giulio; Alberti, Marta; Passoni, Alice; Gaidano, Valentina; Pippione, Agnese C; Vitale, Nicoletta; Bonanni, Davide; Rolando, Barbara; Cignetti, Alessandro; Ramondetti, Cristina; Lanno, Alessia; Ferraris, Davide M; Canepa, Barbara; Buccinnà, Barbara; Piccinini, Marco; Rizzi, Menico; Saglio, Giuseppe; Al-Karadaghi, Salam; Boschi, Donatella; Miggiano, Riccardo; Tuccinardi, Tiziano; Lolli, Marco L
VenomPred: A Machine Learning Based Platform for Molecular Toxicity Predictions
2022-01-01 Galati, Salvatore; Di Stefano, Miriana; Martinelli, Elisa; Macchia, Marco; Martinelli, Adriano; Poli, Giulio; Tuccinardi, Tiziano
Virtual screening and crystallographic studies reveal an unexpected γ-lactone derivative active against MptpB as a potential antitubercular agent
2022-01-01 Cazzaniga, G.; Mori, M.; Meneghetti, F.; Chiarelli, L. R.; Stelitano, G.; Caligiuri, I.; Rizzolio, F.; Ciceri, S.; Poli, G.; Staver, D.; Ortore, G.; Tuccinardi, T.; Villa, S.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Enhanced activity of a pluronic F127 formulated Pin1 inhibitor for ovarian cancer therapy | 1-gen-2023 | Saorin, G.; Mauceri, M.; Cavarzerani, E.; Caligiuri, I.; Bononi, G.; Granchi, C.; Bartoletti, M.; Perin, T.; Tuccinardi, T.; Canzonieri, V.; Adeel, M.; Rizzolio, F. | |
| A carrier free delivery system of a monoacylglycerol lipase hydrophobic inhibitor | 1-gen-2022 | Adeel, Muhammad; Saorin, Gloria; Boccalon, Giacomo; Sfriso, Andrea Augusto; Parisi, Salvatore; Moro, Isabella; Palazzolo, Stefano; Caligiuri, Isabella; Granchi, Carlotta; Corona, Giuseppe; Cemazar, Maja; Canzonieri, Vincenzo; Tuccinardi, Tiziano; Rizzolio, Flavio | |
| Co-Inhibition of P-gp and Hsp90 by an Isatin-Derived Compound Contributes to the Increase of the Chemosensitivity of MCF7/ADR-Resistant Cells to Doxorubicin | 1-gen-2022 | Abdalla, Ashraf N; Di Stefano, Miriana; Poli, Giulio; Tuccinardi, Tiziano; Bader, Ammar; Vassallo, Antonio; Abdallah, Mohamed E; El-Readi, Mahmoud Zaki; Refaat, Bassem; Algarni, Alanood S; Ahmad, Rizwan; Alkahtani, Hamad M; Abdel-Aziz, Alaa A-M; El-Azab, Adel S; Alqathama, Aljawharah | |
| Dissecting the Activity of Catechins as Incomplete Aldose Reductase Differential Inhibitors through Kinetic and Computational Approaches | 1-gen-2022 | Balestri, Francesco; Poli, Giulio; Piazza, Lucia; Cappiello, Mario; Moschini, Roberta; Signore, Giovanni; Tuccinardi, Tiziano; Mura, Umberto; Del Corso, Antonella | |
| Expansion of the 4-(Diethylamino)benzaldehyde Scaffold to Explore the Impact on Aldehyde Dehydrogenase Activity and Antiproliferative Activity in Prostate Cancer | 1-gen-2022 | Ibrahim, Ali I M; Batlle, Elisabet; Sneha, Smarakan; Jiménez, Rafael; Pequerul, Raquel; Parés, Xavier; Rüngeler, Till; Jha, Vibhu; Tuccinardi, Tiziano; Sadiq, Maria; Frame, Fiona; Maitland, Norman J; Farrés, Jaume; Pors, Klaus | |
| From Anti-infective Agents to Cancer Therapy: a Drug Repositioning Study Revealed a New Use for Nitrofuran Derivatives | 1-gen-2022 | Ortore, Gabriella; Poli, Giulio; Martinelli, Adriano; Tuccinardi, Tiziano; Rizzolio, Flavio; Caligiuri, Isabella | |
| Growth performances, chemical composition, and microbiological loads of mealworm reared with brewery spent grains and bread leftovers | 1-gen-2022 | Mancini, S.; Fratini, F.; Provera, I.; Dovicchi, J.; Tuccinardi, T.; Minieri, S.; Papini, R. A.; Forzan, M.; Paci, G. | |
| Historical perspective of tumor glycolysis: a century with Otto Warburg | 1-gen-2022 | Bononi, Giulia; Masoni, Samuele; Di Bussolo, Valeria; Tuccinardi, Tiziano; Granchi, Carlotta; Minutolo, Filippo | |
| Identification of Human Dihydroorotate Dehydrogenase Inhibitor by a Pharmacophore-Based Virtual Screening Study | 1-gen-2022 | Galati, Salvatore; Sainas, Stefano; Giorgis, Marta; Boschi, Donatella; Lolli, Marco L; Ortore, Gabriella; Poli, Giulio; Tuccinardi, Tiziano | |
| Machine Learning-Based Virtual Screening for the Identification of Cdk5 Inhibitors | 1-gen-2022 | Di Stefano, Miriana; Galati, Salvatore; Ortore, Gabriella; Caligiuri, Isabella; Rizzolio, Flavio; Ceni, Costanza; Bertini, Simone; Bononi, Giulia; Granchi, Carlotta; Macchia, Marco; Poli, Giulio; Tuccinardi, Tiziano | |
| New PIN1 inhibitors identified through a pharmacophore-driven, hierarchical consensus docking strategy | 1-gen-2022 | Poli, Giulio; Di Stefano, Miriana; Estevez, Joan Arias; Minutolo, Filippo; Granchi, Carlotta; Giordano, Antonio; Parisi, Salvatore; Mauceri, Matteo; Canzonieri, Vincenzo; Macchia, Marco; Caligiuri, Isabella; Tuccinardi, Tiziano; Rizzolio, Flavio | |
| New Synthetic Analogues of Natural Polyphenols as Sirtuin 1-Activating Compounds | 1-gen-2022 | Bononi, G.; Flori, L.; Citi, V.; Acciai, C.; Nocilla, V.; Martelli, A.; Poli, G.; Tuccinardi, T.; Granchi, C.; Testai, L.; Calderone, V.; Minutolo, F. | |
| Novel Potent and Selective Agonists of the GPR55 Receptor Based on the 3-Benzylquinolin-2(1H)-One Scaffold | 1-gen-2022 | Ceni, Costanza; Benko, Michael J; Mohamed, Kawthar A; Poli, Giulio; Di Stefano, Miriana; Tuccinardi, Tiziano; Digiacomo, Maria; Valoti, Massimo; Laprairie, Robert B; Macchia, Marco; Bertini, Simone | |
| Predicting potentially pathogenic effects of hRPE65 missense mutations: a computational strategy based on molecular dynamics simulations | 1-gen-2022 | Poli, Giulio; Barravecchia, Ivana; Demontis, Gian Carlo; Sodi, Andrea; Saba, Alessandro; Rizzo, Stanislao; Macchia, Marco; Tuccinardi, Tiziano | |
| Resveratrol Analogues as Dual Inhibitors of Monoamine Oxidase B and Carbonic Anhydrase VII: A New Multi-Target Combination for Neurodegenerative Diseases? | 1-gen-2022 | Carradori, Simone; Fantacuzzi, Marialuigia; Ammazzalorso, Alessandra; Angeli, Andrea; De Filippis, Barbara; Galati, Salvatore; Petzer, Anél; Petzer, Jacobus P; Poli, Giulio; Tuccinardi, Tiziano; Agamennone, Mariangela; Supuran, Claudiu T | |
| Reversible Monoacylglycerol Lipase Inhibitors: Discovery of a New Class of Benzylpiperidine Derivatives | 1-gen-2022 | Bononi, Giulia; Di Stefano, Miriana; Poli, Giulio; Ortore, Gabriella; Meier, Philip; Masetto, Francesca; Caligiuri, Isabella; Rizzolio, Flavio; Macchia, Marco; Chicca, Andrea; Avan, Amir; Giovannetti, Elisa; Vagaggini, Chiara; Brai, Annalaura; Dreassi, Elena; Valoti, Massimo; Minutolo, Filippo; Granchi, Carlotta; Gertsch, Jürg; Tuccinardi, Tiziano | |
| Sirtuin 1-Activating Compounds: Discovery of a Class of Thiazole-Based Derivatives | 1-gen-2022 | Bononi, G.; Citi, V.; Lapillo, M.; Martelli, A.; Poli, G.; Tuccinardi, T.; Granchi, C.; Testai, L.; Calderone, V.; Minutolo, F. | |
| Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Aryloxyaryl Moiety | 1-gen-2022 | Sainas, Stefano; Giorgis, Marta; Circosta, Paola; Poli, Giulio; Alberti, Marta; Passoni, Alice; Gaidano, Valentina; Pippione, Agnese C; Vitale, Nicoletta; Bonanni, Davide; Rolando, Barbara; Cignetti, Alessandro; Ramondetti, Cristina; Lanno, Alessia; Ferraris, Davide M; Canepa, Barbara; Buccinnà, Barbara; Piccinini, Marco; Rizzi, Menico; Saglio, Giuseppe; Al-Karadaghi, Salam; Boschi, Donatella; Miggiano, Riccardo; Tuccinardi, Tiziano; Lolli, Marco L | |
| VenomPred: A Machine Learning Based Platform for Molecular Toxicity Predictions | 1-gen-2022 | Galati, Salvatore; Di Stefano, Miriana; Martinelli, Elisa; Macchia, Marco; Martinelli, Adriano; Poli, Giulio; Tuccinardi, Tiziano | |
| Virtual screening and crystallographic studies reveal an unexpected γ-lactone derivative active against MptpB as a potential antitubercular agent | 1-gen-2022 | Cazzaniga, G.; Mori, M.; Meneghetti, F.; Chiarelli, L. R.; Stelitano, G.; Caligiuri, I.; Rizzolio, F.; Ciceri, S.; Poli, G.; Staver, D.; Ortore, G.; Tuccinardi, T.; Villa, S. |