TUCCINARDI, TIZIANO Statistiche
TUCCINARDI, TIZIANO
DIPARTIMENTO DI FARMACIA
A carrier free delivery system of a MAGL inhibitor is effective on ovarian cancer
2024-01-01 Palazzolo, Stefano; Saorin, Gloria; Corona, Giuseppe; Granchi, Carlotta; Tuccinardi, Tiziano; Kamensek, Urska; Brezar, Simona Kranjc; Cemazar, Maja; Canzonieri, Vincenzo; Rizzolio, Flavio
A comprehensive review of synthetic strategies and SAR studies for the discovery of PfDHODH inhibitors as antimalarial agents. Part 1: triazolopyrimidine, isoxazolopyrimidine and pyrrole-based (DSM) compounds
2024-01-01 Sharma, Manmohan; Pandey, Vinita; Poli, Giulio; Tuccinardi, Tiziano; Lolli, Marco L; Vyas, Vivek K
A patent review of lactate dehydrogenase inhibitors (2014-present)
2024-01-01 Bononi, Giulia; Di Bussolo, Valeria; Tuccinardi, Tiziano; Minutolo, Filippo; Granchi, Carlotta
An alternative conformation of the N-terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent
2024-01-01 Alberti, Marta; Poli, Giulio; Broggini, Luca; Sainas, Stefano; Rizzi, Menico; Boschi, Donatella; Ferraris, Davide M; Martino, Elena; Ricagno, Stefano; Tuccinardi, Tiziano; Lolli, Marco L; Miggiano, Riccardo
Chemical composition, fatty acid profile, antioxidant content, and microbiological loads of lesser mealworm, mealworm, and superworm larvae
2024-01-01 Mattioli, Simona; Fratini, Filippo; Cacchiarelli, Chiara; Martinis, Valentina; Tuccinardi, Tiziano; Paci, Gisella; Dal Bosco, Alessandro; Mancini, Simone
Design, synthesis and biological evaluation of arylsulfonamides as ADAMTS7 inhibitors
2024-01-01 Cuffaro, Doretta; Burkhard, Tina; Bernardoni, Bianca Laura; Di Leo, Riccardo; Zhang, Xiaohan; Galati, Salvatore; Tuccinardi, Tiziano; Macchia, Marco; Rossello, Armando; Santamaria, Salvatore; de Groot, Rens; Nuti, Elisa
Design, synthesis, ADME and biological evaluation of benzylpiperidine and benzylpiperazine derivatives as novel reversible monoacylglycerol lipase (MAGL) inhibitors
2024-01-01 Di Stefano, Miriana; Masoni, Samuele; Bononi, Giulia; Poli, Giulio; Galati, Salvatore; Gado, Francesca; Manzi, Simone; Vagaggini, Chiara; Brai, Annalaura; Caligiuri, Isabella; Asif, Kanwal; Rizzolio, Flavio; Macchia, Marco; Chicca, Andrea; Sodi, Andrea; Di Bussolo, Valeria; Minutolo, Filippo; Meier, Philip; Gertsch, Jürg; Granchi, Carlotta; Dreassi, Elena; Tuccinardi, Tiziano
Nuovi agenti antivirali a struttura N-idrossiindrol-carbossamidica
2024-01-01 Minutolo, Filippo; Pistello, Mauro; DI BUSSOLO, Valeria; Freer, Giulia; Quaranta, Paola; Granchi, Carlotta; Tuccinardi, Tiziano; Poli, Giulio; Bononi, Giulia; Masoni, Samuele
Sirtuin 1-activating derivatives belonging to the anilinopyridine class displaying in vivo cardioprotective activities
2024-01-01 Bononi, G.; Citi, V.; Martelli, A.; Poli, G.; Tuccinardi, T.; Granchi, C.; Testai, L.; Calderone, V.; Minutolo, F.
SMS121, a new inhibitor of CD36, impairs fatty acid uptake and viability of acute myeloid leukemia
2024-01-01 Åbacka, Hannah; Masoni, Samuele; Poli, Giulio; Huang, Peng; Gusso, Francesco; Granchi, Carlotta; Minutolo, Filippo; Tuccinardi, Tiziano; Hagström-Andersson, Anna K; Lindkvist-Petersson, Karin
Synthesis and pharmacological evaluation of novel N-aryl-cinnamoyl-hydrazone hybrids designed as neuroprotective agents for the treatment of Parkinson's disease
2024-01-01 de Freitas Silva, Matheus; Juliet Cristancho Ortiz, Cindy; Ferreira Coelho, Letícia; Pruccoli, Letizia; Pagliarani, Barbara; Pisani, Leonardo; Catto, Marco; Poli, Giulio; Tuccinardi, Tiziano; Cardoso Vilela, Fabiana; Giusti-Paiva, Alexandre; Amaral Alves, Marina; Ribeiro de Souza, Hygor M; Tarozzi, Andrea; Silva Gontijo, Vanessa; Viegas, Claudio
The Benzoylpiperidine Fragment as a Privileged Structure in Medicinal Chemistry: A Comprehensive Review
2024-01-01 Bononi, Giulia; Lonzi, Chiara; Tuccinardi, Tiziano; Minutolo, Filippo; Granchi, Carlotta
VenomPred 2.0: A Novel In Silico Platform for an Extended and Human Interpretable Toxicological Profiling of Small Molecules
2024-01-01 Di Stefano, Miriana; Galati, Salvatore; Piazza, Lisa; Granchi, Carlotta; Mancini, Simone; Fratini, Filippo; Macchia, Marco; Poli, Giulio; Tuccinardi, Tiziano
WaSPred: A reliable AI-based water solubility predictor for small molecules
2024-01-01 Di Stefano, Miriana; Galati, Salvatore; Lonzi, Chiara; Granchi, Carlotta; Poli, Giulio; Tuccinardi, Tiziano; Macchia, Marco
Watermelon: setup and validation of an in silico fragment-based approach
2024-01-01 Di Stefano, Miriana; Galati, Salvatore; Piazza, Lisa; Gado, Francesca; Granchi, Carlotta; Macchia, Marco; Giordano, Antonio; Tuccinardi, Tiziano; Poli, Giulio
A Multitarget Approach against Neuroinflammation: Alkyl Substituted Coumarins as Inhibitors of Enzymes Involved in Neurodegeneration
2023-01-01 Berrino, Emanuela; Carradori, Simone; Carta, Fabrizio; Melfi, Francesco; Gallorini, Marialucia; Poli, Giulio; Tuccinardi, Tiziano; Fernández-Bolaños, José G; López, Óscar; Petzer, Jacobus P; Petzer, Anél; Guglielmi, Paolo; Secci, Daniela; Supuran, Claudiu T
An in silico toolbox for the prediction of the potential pathogenic effects of missense mutations in the dimeric region of hRPE65
2023-01-01 Poli, Giulio; Demontis, Gian Carlo; Sodi, Andrea; Saba, Alessandro; Rizzo, Stanislao; Macchia, Marco; Tuccinardi, Tiziano
Enhanced activity of a pluronic F127 formulated Pin1 inhibitor for ovarian cancer therapy
2023-01-01 Saorin, G.; Mauceri, M.; Cavarzerani, E.; Caligiuri, I.; Bononi, G.; Granchi, C.; Bartoletti, M.; Perin, T.; Tuccinardi, T.; Canzonieri, V.; Adeel, M.; Rizzolio, F.
Identification of New GSK3β Inhibitors through a Consensus Machine Learning-Based Virtual Screening
2023-01-01 Galati, Salvatore; Di Stefano, Miriana; Bertini, Simone; Granchi, Carlotta; Giordano, Antonio; Gado, Francesca; Macchia, Marco; Tuccinardi, Tiziano; Poli, Giulio
miRNA-203b-3p Induces Acute and Chronic Pruritus through 5-HTR2B and TRPV4
2023-01-01 De Logu, Francesco; Maglie, Roberto; Titiz, Mustafa; Poli, Giulio; Landini, Lorenzo; Marini, Matilde; Souza Monteiro de Araujo, Daniel; De Siena, Gaetano; Montini, Marco; Cabrini, Daniela Almeida; Otuki, Michel Fleith; Pawloski, Priscila Lúcia; Antiga, Emiliano; Tuccinardi, Tiziano; Calixto, João Batista; Geppetti, Pierangelo; Nassini, Romina; André, Eunice
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A carrier free delivery system of a MAGL inhibitor is effective on ovarian cancer | 1-gen-2024 | Palazzolo, Stefano; Saorin, Gloria; Corona, Giuseppe; Granchi, Carlotta; Tuccinardi, Tiziano; Kamensek, Urska; Brezar, Simona Kranjc; Cemazar, Maja; Canzonieri, Vincenzo; Rizzolio, Flavio | |
| A comprehensive review of synthetic strategies and SAR studies for the discovery of PfDHODH inhibitors as antimalarial agents. Part 1: triazolopyrimidine, isoxazolopyrimidine and pyrrole-based (DSM) compounds | 1-gen-2024 | Sharma, Manmohan; Pandey, Vinita; Poli, Giulio; Tuccinardi, Tiziano; Lolli, Marco L; Vyas, Vivek K | |
| A patent review of lactate dehydrogenase inhibitors (2014-present) | 1-gen-2024 | Bononi, Giulia; Di Bussolo, Valeria; Tuccinardi, Tiziano; Minutolo, Filippo; Granchi, Carlotta | |
| An alternative conformation of the N-terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent | 1-gen-2024 | Alberti, Marta; Poli, Giulio; Broggini, Luca; Sainas, Stefano; Rizzi, Menico; Boschi, Donatella; Ferraris, Davide M; Martino, Elena; Ricagno, Stefano; Tuccinardi, Tiziano; Lolli, Marco L; Miggiano, Riccardo | |
| Chemical composition, fatty acid profile, antioxidant content, and microbiological loads of lesser mealworm, mealworm, and superworm larvae | 1-gen-2024 | Mattioli, Simona; Fratini, Filippo; Cacchiarelli, Chiara; Martinis, Valentina; Tuccinardi, Tiziano; Paci, Gisella; Dal Bosco, Alessandro; Mancini, Simone | |
| Design, synthesis and biological evaluation of arylsulfonamides as ADAMTS7 inhibitors | 1-gen-2024 | Cuffaro, Doretta; Burkhard, Tina; Bernardoni, Bianca Laura; Di Leo, Riccardo; Zhang, Xiaohan; Galati, Salvatore; Tuccinardi, Tiziano; Macchia, Marco; Rossello, Armando; Santamaria, Salvatore; de Groot, Rens; Nuti, Elisa | |
| Design, synthesis, ADME and biological evaluation of benzylpiperidine and benzylpiperazine derivatives as novel reversible monoacylglycerol lipase (MAGL) inhibitors | 1-gen-2024 | Di Stefano, Miriana; Masoni, Samuele; Bononi, Giulia; Poli, Giulio; Galati, Salvatore; Gado, Francesca; Manzi, Simone; Vagaggini, Chiara; Brai, Annalaura; Caligiuri, Isabella; Asif, Kanwal; Rizzolio, Flavio; Macchia, Marco; Chicca, Andrea; Sodi, Andrea; Di Bussolo, Valeria; Minutolo, Filippo; Meier, Philip; Gertsch, Jürg; Granchi, Carlotta; Dreassi, Elena; Tuccinardi, Tiziano | |
| Nuovi agenti antivirali a struttura N-idrossiindrol-carbossamidica | 1-gen-2024 | Minutolo, Filippo; Pistello, Mauro; DI BUSSOLO, Valeria; Freer, Giulia; Quaranta, Paola; Granchi, Carlotta; Tuccinardi, Tiziano; Poli, Giulio; Bononi, Giulia; Masoni, Samuele | |
| Sirtuin 1-activating derivatives belonging to the anilinopyridine class displaying in vivo cardioprotective activities | 1-gen-2024 | Bononi, G.; Citi, V.; Martelli, A.; Poli, G.; Tuccinardi, T.; Granchi, C.; Testai, L.; Calderone, V.; Minutolo, F. | |
| SMS121, a new inhibitor of CD36, impairs fatty acid uptake and viability of acute myeloid leukemia | 1-gen-2024 | Åbacka, Hannah; Masoni, Samuele; Poli, Giulio; Huang, Peng; Gusso, Francesco; Granchi, Carlotta; Minutolo, Filippo; Tuccinardi, Tiziano; Hagström-Andersson, Anna K; Lindkvist-Petersson, Karin | |
| Synthesis and pharmacological evaluation of novel N-aryl-cinnamoyl-hydrazone hybrids designed as neuroprotective agents for the treatment of Parkinson's disease | 1-gen-2024 | de Freitas Silva, Matheus; Juliet Cristancho Ortiz, Cindy; Ferreira Coelho, Letícia; Pruccoli, Letizia; Pagliarani, Barbara; Pisani, Leonardo; Catto, Marco; Poli, Giulio; Tuccinardi, Tiziano; Cardoso Vilela, Fabiana; Giusti-Paiva, Alexandre; Amaral Alves, Marina; Ribeiro de Souza, Hygor M; Tarozzi, Andrea; Silva Gontijo, Vanessa; Viegas, Claudio | |
| The Benzoylpiperidine Fragment as a Privileged Structure in Medicinal Chemistry: A Comprehensive Review | 1-gen-2024 | Bononi, Giulia; Lonzi, Chiara; Tuccinardi, Tiziano; Minutolo, Filippo; Granchi, Carlotta | |
| VenomPred 2.0: A Novel In Silico Platform for an Extended and Human Interpretable Toxicological Profiling of Small Molecules | 1-gen-2024 | Di Stefano, Miriana; Galati, Salvatore; Piazza, Lisa; Granchi, Carlotta; Mancini, Simone; Fratini, Filippo; Macchia, Marco; Poli, Giulio; Tuccinardi, Tiziano | |
| WaSPred: A reliable AI-based water solubility predictor for small molecules | 1-gen-2024 | Di Stefano, Miriana; Galati, Salvatore; Lonzi, Chiara; Granchi, Carlotta; Poli, Giulio; Tuccinardi, Tiziano; Macchia, Marco | |
| Watermelon: setup and validation of an in silico fragment-based approach | 1-gen-2024 | Di Stefano, Miriana; Galati, Salvatore; Piazza, Lisa; Gado, Francesca; Granchi, Carlotta; Macchia, Marco; Giordano, Antonio; Tuccinardi, Tiziano; Poli, Giulio | |
| A Multitarget Approach against Neuroinflammation: Alkyl Substituted Coumarins as Inhibitors of Enzymes Involved in Neurodegeneration | 1-gen-2023 | Berrino, Emanuela; Carradori, Simone; Carta, Fabrizio; Melfi, Francesco; Gallorini, Marialucia; Poli, Giulio; Tuccinardi, Tiziano; Fernández-Bolaños, José G; López, Óscar; Petzer, Jacobus P; Petzer, Anél; Guglielmi, Paolo; Secci, Daniela; Supuran, Claudiu T | |
| An in silico toolbox for the prediction of the potential pathogenic effects of missense mutations in the dimeric region of hRPE65 | 1-gen-2023 | Poli, Giulio; Demontis, Gian Carlo; Sodi, Andrea; Saba, Alessandro; Rizzo, Stanislao; Macchia, Marco; Tuccinardi, Tiziano | |
| Enhanced activity of a pluronic F127 formulated Pin1 inhibitor for ovarian cancer therapy | 1-gen-2023 | Saorin, G.; Mauceri, M.; Cavarzerani, E.; Caligiuri, I.; Bononi, G.; Granchi, C.; Bartoletti, M.; Perin, T.; Tuccinardi, T.; Canzonieri, V.; Adeel, M.; Rizzolio, F. | |
| Identification of New GSK3β Inhibitors through a Consensus Machine Learning-Based Virtual Screening | 1-gen-2023 | Galati, Salvatore; Di Stefano, Miriana; Bertini, Simone; Granchi, Carlotta; Giordano, Antonio; Gado, Francesca; Macchia, Marco; Tuccinardi, Tiziano; Poli, Giulio | |
| miRNA-203b-3p Induces Acute and Chronic Pruritus through 5-HTR2B and TRPV4 | 1-gen-2023 | De Logu, Francesco; Maglie, Roberto; Titiz, Mustafa; Poli, Giulio; Landini, Lorenzo; Marini, Matilde; Souza Monteiro de Araujo, Daniel; De Siena, Gaetano; Montini, Marco; Cabrini, Daniela Almeida; Otuki, Michel Fleith; Pawloski, Priscila Lúcia; Antiga, Emiliano; Tuccinardi, Tiziano; Calixto, João Batista; Geppetti, Pierangelo; Nassini, Romina; André, Eunice |