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A combined approach of structure-based virtual screening and NMR to interrupt the PD-1/PD-L1 axis: Biphenyl-benzimidazole containing compounds as novel PD-L1 inhibitors 1-gen-2023 Donati, Greta; Viviano, Monica; D'Amore, Vincenzo Maria; Cipriano, Alessandra; Diakogiannaki, Isidora; Amato, Jussara; Tomassi, Stefano; Brancaccio, Diego; Russomanno, Pasquale; Di Leva, Francesco Saverio; Arosio, Daniela; Seneci, Pierfausto; Taliani, Sabrina; Magiera-Mularz, Katarzyna; Musielak, Bogdan; Skalniak, Lukasz; Holak, Tad A.; Castellano, Sabrina; La Pietra, Valeria; Marinelli, Luciana
A complex bearing TSPO PIGA ligand coordinated to the [Au(PEt3)]+ pharmacophore is highly cytotoxic against ovarian cancer cells 1-gen-2023 Chiaverini, Lorenzo; Baglini, Emma; Mannelli, Michele; Poggetti, Valeria; Da Settimo, Federico; Taliani, Sabrina; Gamberi, Tania; Barresi, Elisabetta; La Mendola, Diego; Marzo, Tiziano
A cyanine-based NIR fluorescent Vemurafenib analog to probe BRAFV600E in cancer cells 1-gen-2023 Barresi, Elisabetta; Baldanzi, Caterina; Roncetti, Marta; Roggia, Michele; Baglini, Emma; Lepori, Irene; Vitiello, Marianna; Salerno, Silvia; Tedeschi, Lorena; Da Settimo, Federico; Cosconati, Sandro; Poliseno, Laura; Taliani, Sabrina
Anti-Proliferative Properties of the Novel Hybrid Drug Met-ITC, Composed of the Native Drug Metformin with the Addition of an Isothiocyanate H2S Donor Moiety, in Different Cancer Cell Lines 1-gen-2023 Citi, V.; Barresi, E.; Piragine, E.; Spezzini, J.; Testai, L.; Da Settimo, F.; Martelli, A.; Taliani, S.; Calderone, V.
Diruthenium(ii,iii) paddlewheel complexes: effects of bridging and axial ligands on anticancer properties 1-gen-2023 Tolbatov, I; Barresi, E; Taliani, S; La Mendola, D; Marzo, T; Marrone, A
Indol-3-ylglyoxylamide as Privileged Scaffold in Medicinal Chemistry 1-gen-2023 Barresi, E.; Robello, M.; Baglini, E.; Poggetti, V.; Viviano, M.; Salerno, S.; Da Settimo, F.; Taliani, S.
Target-Based Anticancer Indole Derivatives for the Development of Anti-Glioblastoma Agents 1-gen-2023 Salerno, Silvia; Barresi, Elisabetta; Baglini, Emma; Poggetti, Valeria; Da Settimo, Federico; Taliani, Sabrina
The human microglial surveillant phenotype is preserved by de novo neurosteroidogenesis through the control of cholesterol homeostasis: Crucial role of 18 kDa Translocator Protein 1-gen-2023 Angeloni, Elisa; Germelli, Lorenzo; Marchetti, Laura; Da Pozzo, Eleonora; Tremolanti, Chiara; Wetzel, Christian H; Baglini, Emma; Taliani, Sabrina; Da Settimo, Federico; Martini, Claudia; Costa, Barbara
Tyrosine kinase inhibitors (TKIs) for ovarian cancer treatment: from organic to inorganic chemotherapeutics towards selectivity-a perspective overview 1-gen-2023 Baglini, Emma; Chiaverini, Lorenzo; Tolbatov, Iogann; Taliani, Sabrina; Da Settimo, Federico; La Mendola, Diego; Barresi, Elisabetta; Marzo, Tiziano
Allosteric Modulators of Adenosine Receptors 1-gen-2022 Barresi, Elisabetta; Giacomelli, Chiara; Martini, Claudia; Da Settimo, Federico; Trincavelli, Maria Letizia; Taliani, Sabrina
Cancer Immunotherapy: An Overview on Small Molecules as Inhibitors of the Immune Checkpoint PD-1/PD-L1 (2015-2021) 1-gen-2022 Baglini, Emma; Salerno, Silvia; Barresi, Elisabetta; Marzo, Tiziano; Settimo, Federico Da; Taliani, Sabrina
Carbonic Anhydrase Activators for Neurodegeneration: An Overview 1-gen-2022 Poggetti, V.; Salerno, S.; Baglini, E.; Barresi, E.; Da Settimo, F.; Taliani, S.
Dual Targeting Topoisomerase/G-Quadruplex Agents in Cancer Therapy-An Overview 1-gen-2022 Salerno, Silvia; Barresi, Elisabetta; Baglini, Emma; Poggetti, Valeria; Taliani, Sabrina; Da Settimo, Federico
Essential Principles and Recent Progress in the Development of TSPO PET Ligands for Neuroinflammation Imaging 1-gen-2022 Viviano, Monica; Barresi, Elisabetta; Siméon, Fabrice G; Costa, Barbara; Taliani, Sabrina; Da Settimo, Federico; Pike, Victor W; Castellano, Sabrina
New antiproliferative agents derived from tricyclic 3,4-dihydrobenzo[4,5]imidazo[1,2-a][1,3,5]triazine scaffold: synthesis and pharmacological effects 1-gen-2022 Robello, Marco; Salerno, Silvia; Barresi, Elisabetta; Orlandi, Paola; Vaglini, Francesca; Banchi, Marta; Simorini, Francesca; Baglini, Emma; Poggetti, Valeria; Taliani, Sabrina; DA SETTIMO PASSETTI, Federico; Bocci, Guido
Targeting TSPO Reduces Inflammation and Apoptosis in an In Vitro Photoreceptor-Like Model of Retinal Degeneration 1-gen-2022 Corsi, Francesca; Baglini, Emma; Barresi, Elisabetta; Salerno, Silvia; Cerri, Chiara; Martini, Claudia; Da Settimo Passetti, Federico; Taliani, Sabrina; Gargini, Claudia; Piano, Ilaria
Translocator Protein 18-kDa: a promising target to treat neuroinflammation-related degenerative diseases 1-gen-2022 Tremolanti, Chiara; Germelli, Lorenzo; Barresi, Elisabetta; Da Pozzo, Eleonora; Simorini, Francesca; Castellano, Sabrina; Taliani, Sabrina; Da Settimo, Federico; Martini, Claudia; Costa, Barbara
Translocator Protein Ligand PIGA1138 Reduces Disease Symptoms and Severity in Experimental Autoimmune Encephalomyelitis Model of Primary Progressive Multiple Sclerosis 1-gen-2022 Tremolanti, C.; Cavallini, C.; Meyer, L.; Klein, C.; Da Pozzo, E.; Costa, B.; Germelli, L.; Taliani, S.; Patte-Mensah, C.; Mensah-Nyagan, A. -G.
Allosterism vs. Orthosterism: Recent Findings and Future Perspectives on A2B AR Physio-Pathological Implications 1-gen-2021 Barresi, E.; Martini, C.; Da Settimo, F.; Greco, G.; Taliani, S.; Giacomelli, C.; Trincavelli, M. L.
An update into the medicinal chemistry of translocator protein (TSPO) ligands 1-gen-2021 Barresi, E.; Robello, M.; Costa, B.; Da Pozzo, E.; Baglini, E.; Salerno, S.; Da Settimo, F.; Martini, C.; Taliani, S.