ORTORE, GABRIELLA MARIA PIA Statistiche
ORTORE, GABRIELLA MARIA PIA
DIPARTIMENTO DI FARMACIA
New Insights into Bitopic Orthosteric/Allosteric Ligands of Cannabinoid Receptor Type 2
2023-01-01 Ferrisi, Rebecca; Polini, Beatrice; Ricardi, Caterina; Gado, Francesca; Mohamed, Kawthar A; Baron, Giovanna; Faiella, Salvatore; Poli, Giulio; Rapposelli, Simona; Saccomanni, Giuseppe; Aldini, Giancarlo; Chiellini, Grazia; Laprairie, Robert B; Manera, Clementina; Ortore, Gabriella
Thyroxine metabolite-derived 3-iodothyronamine (T1AM) and synthetic analogs as efficient suppressors of transthyretin amyloidosis
2023-01-01 Kim, Bokyung; Ho Ko, Young; Si, Jinbeom; Na, Jongbum; Ortore, Gabriella; Chiellini, Grazia; Hae Kim, Jin
CB1 receptor binding sites for NAM and PAM: A first approach for studying, new n‑butyl‑diphenylcarboxamides as allosteric modulators
2022-01-01 Gado, F.; Ceni, C.; Ferrisi, R.; Sbrana, G.; Stevenson, L. A.; Macchia, M.; Pertwee, R. G.; Bertini, S.; Manera, C.; Ortore, G.
Design, synthesis and biological evaluation of novel orthosteric-allosteric ligands of the cannabinoid receptor type 2 (CB2R)
2022-01-01 Ferrisi, Rebecca; Gado, Francesca; Polini, Beatrice; Ricardi, Caterina; Mohamed, Kawthar A.; Stevenson, Lesley A.; Ortore, Gabriella; Rapposelli, Simona; Saccomanni, Giuseppe; Pertwee, Roger G.; Laprairie, Robert B.; Manera, Clementina; Chiellini, Grazia
Design, Synthesis, and Biological Activity of New CB2 Receptor Ligands: from Orthosteric and Allosteric Modulators to Dualsteric/Bitopic Ligands
2022-01-01 Gado, Francesca; Ferrisi, Rebecca; Polini, Beatrice; Mohamed, Kawthar A.; Ricardi, Caterina; Lucarini, Elena; Carpi, Sara; Domenichini, Federica; Stevenson, Lesley A.; Rapposelli, Simona; Saccomanni, Giuseppe; Nieri, Paola; Ortore, Gabriella; Pertwee, Roger G.; Ghelardini, Carla; Di Cesare Mannelli, Lorenzo; Chiellini, Grazia; Laprairie, Robert B.; Manera, Clementina
From Anti-infective Agents to Cancer Therapy: a Drug Repositioning Study Revealed a New Use for Nitrofuran Derivatives
2022-01-01 Ortore, Gabriella; Poli, Giulio; Martinelli, Adriano; Tuccinardi, Tiziano; Rizzolio, Flavio; Caligiuri, Isabella
Identification of Human Dihydroorotate Dehydrogenase Inhibitor by a Pharmacophore-Based Virtual Screening Study
2022-01-01 Galati, Salvatore; Sainas, Stefano; Giorgis, Marta; Boschi, Donatella; Lolli, Marco L; Ortore, Gabriella; Poli, Giulio; Tuccinardi, Tiziano
Machine Learning-Based Virtual Screening for the Identification of Cdk5 Inhibitors
2022-01-01 Di Stefano, Miriana; Galati, Salvatore; Ortore, Gabriella; Caligiuri, Isabella; Rizzolio, Flavio; Ceni, Costanza; Bertini, Simone; Bononi, Giulia; Granchi, Carlotta; Macchia, Marco; Poli, Giulio; Tuccinardi, Tiziano
Reversible Monoacylglycerol Lipase Inhibitors: Discovery of a New Class of Benzylpiperidine Derivatives
2022-01-01 Bononi, Giulia; Di Stefano, Miriana; Poli, Giulio; Ortore, Gabriella; Meier, Philip; Masetto, Francesca; Caligiuri, Isabella; Rizzolio, Flavio; Macchia, Marco; Chicca, Andrea; Avan, Amir; Giovannetti, Elisa; Vagaggini, Chiara; Brai, Annalaura; Dreassi, Elena; Valoti, Massimo; Minutolo, Filippo; Granchi, Carlotta; Gertsch, Jürg; Tuccinardi, Tiziano
Synthesis and Evaluation of Monoaryl Derivatives as Transthyretin Fibril Formation Inhibitors
2022-01-01 Ciccone, Lidia; Nencetti, Susanna; Camodeca, Caterina; Ortore, Gabriella; Cuffaro, Doretta; Socci, Simone; Orlandini, Elisabetta
Virtual screening and crystallographic studies reveal an unexpected γ-lactone derivative active against MptpB as a potential antitubercular agent
2022-01-01 Cazzaniga, G.; Mori, M.; Meneghetti, F.; Chiarelli, L. R.; Stelitano, G.; Caligiuri, I.; Rizzolio, F.; Ciceri, S.; Poli, G.; Staver, D.; Ortore, G.; Tuccinardi, T.; Villa, S.
Diphenyl-methane based thyromimetic inhibitors for transthyretin amyloidosis
2021-01-01 Kim, B.; Ko, Y. H.; Runfola, M.; Rapposelli, S.; Ortore, G.; Chiellini, G.; Kim, J. H.
Focus on Human Monoamine Transporter Selectivity. New Human DAT and NET Models, Experimental Validation, and SERT Affinity Exploration
2020-01-01 Ortore, G.; Orlandini, E.; Betti, L.; Giannaccini, G.; Mazzoni, M. R.; Camodeca, C.; Nencetti, S.
Identification of histone deacetylase inhibitors with (arylidene)aminoxy scaffold active in uveal melanoma cell lines
2020-01-01 Nencetti, S.; Cuffaro, D.; Nuti, E.; Ciccone, L.; Rossello, A.; Fabbi, M.; Ballante, F.; Ortore, G.; Carbotti, G.; Campelli, F.; Banti, I.; Gangemi, R.; Marshall, G. R.; Orlandini, E.
Discovery of Novel Adenosine Receptor Antagonists through a Combined Structure- and Ligand-Based Approach Followed by Molecular Dynamics Investigation of Ligand Binding Mode
2018-01-01 Lagarias, Panagiotis; Vrontaki, Eleni; Lambrinidis, George; Stamatis, Dimitrios; Convertino, Marino; Ortore, Gabriella; Mavromoustakos, Thomas; Klotz, Karl-Norbert; Kolocouris, Antonios
Identification of Transthyretin Fibril Formation Inhibitors Using Structure-Based Virtual Screening
2017-01-01 Ortore, GABRIELLA MARIA PIA; Martinelli, Adriano
A STRUCTURE-BASED VIRTUAL SCREENING TO IDENTIFY NEW SCAFFOLDS FOR TRANSTHYRETIN FIBRIL FORMATION INHIBITORS
2016-01-01 Ortore, G.; Martinelli, A.
A Virtual Screening Study for Lactate Dehydrogenase 5 Inhibitors by using a Pharmacophore-Based Approach
2016-01-01 Tuccinardi, Tiziano; Poli, Giulio; Corchia, Isacco; Granchi, Carlotta; Lapillo, Margherita; Macchia, Marco; Minutolo, Filippo; Ortore, GABRIELLA MARIA PIA; Martinelli, Adriano
Exploring the binding of quercetin-3-O-metabolites with transthyretin
2016-01-01 Ortore, GABRIELLA MARIA PIA; Ciccone, Lidia; Orlandini, Elisabetta; Stura, E.; Braca, Alessandra; Rossello, Armando; Nencetti, Susanna
Targeting Different Transthyretin Binding Sites with Unusual Natural Compounds
2016-01-01 Ortore, GABRIELLA MARIA PIA; Orlandini, Elisabetta; Braca, Alessandra; Ciccone, Lidia; Rossello, Armando; Martinelli, Adriano; Nencetti, Susanna
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| New Insights into Bitopic Orthosteric/Allosteric Ligands of Cannabinoid Receptor Type 2 | 1-gen-2023 | Ferrisi, Rebecca; Polini, Beatrice; Ricardi, Caterina; Gado, Francesca; Mohamed, Kawthar A; Baron, Giovanna; Faiella, Salvatore; Poli, Giulio; Rapposelli, Simona; Saccomanni, Giuseppe; Aldini, Giancarlo; Chiellini, Grazia; Laprairie, Robert B; Manera, Clementina; Ortore, Gabriella | |
| Thyroxine metabolite-derived 3-iodothyronamine (T1AM) and synthetic analogs as efficient suppressors of transthyretin amyloidosis | 1-gen-2023 | Kim, Bokyung; Ho Ko, Young; Si, Jinbeom; Na, Jongbum; Ortore, Gabriella; Chiellini, Grazia; Hae Kim, Jin | |
| CB1 receptor binding sites for NAM and PAM: A first approach for studying, new n‑butyl‑diphenylcarboxamides as allosteric modulators | 1-gen-2022 | Gado, F.; Ceni, C.; Ferrisi, R.; Sbrana, G.; Stevenson, L. A.; Macchia, M.; Pertwee, R. G.; Bertini, S.; Manera, C.; Ortore, G. | |
| Design, synthesis and biological evaluation of novel orthosteric-allosteric ligands of the cannabinoid receptor type 2 (CB2R) | 1-gen-2022 | Ferrisi, Rebecca; Gado, Francesca; Polini, Beatrice; Ricardi, Caterina; Mohamed, Kawthar A.; Stevenson, Lesley A.; Ortore, Gabriella; Rapposelli, Simona; Saccomanni, Giuseppe; Pertwee, Roger G.; Laprairie, Robert B.; Manera, Clementina; Chiellini, Grazia | |
| Design, Synthesis, and Biological Activity of New CB2 Receptor Ligands: from Orthosteric and Allosteric Modulators to Dualsteric/Bitopic Ligands | 1-gen-2022 | Gado, Francesca; Ferrisi, Rebecca; Polini, Beatrice; Mohamed, Kawthar A.; Ricardi, Caterina; Lucarini, Elena; Carpi, Sara; Domenichini, Federica; Stevenson, Lesley A.; Rapposelli, Simona; Saccomanni, Giuseppe; Nieri, Paola; Ortore, Gabriella; Pertwee, Roger G.; Ghelardini, Carla; Di Cesare Mannelli, Lorenzo; Chiellini, Grazia; Laprairie, Robert B.; Manera, Clementina | |
| From Anti-infective Agents to Cancer Therapy: a Drug Repositioning Study Revealed a New Use for Nitrofuran Derivatives | 1-gen-2022 | Ortore, Gabriella; Poli, Giulio; Martinelli, Adriano; Tuccinardi, Tiziano; Rizzolio, Flavio; Caligiuri, Isabella | |
| Identification of Human Dihydroorotate Dehydrogenase Inhibitor by a Pharmacophore-Based Virtual Screening Study | 1-gen-2022 | Galati, Salvatore; Sainas, Stefano; Giorgis, Marta; Boschi, Donatella; Lolli, Marco L; Ortore, Gabriella; Poli, Giulio; Tuccinardi, Tiziano | |
| Machine Learning-Based Virtual Screening for the Identification of Cdk5 Inhibitors | 1-gen-2022 | Di Stefano, Miriana; Galati, Salvatore; Ortore, Gabriella; Caligiuri, Isabella; Rizzolio, Flavio; Ceni, Costanza; Bertini, Simone; Bononi, Giulia; Granchi, Carlotta; Macchia, Marco; Poli, Giulio; Tuccinardi, Tiziano | |
| Reversible Monoacylglycerol Lipase Inhibitors: Discovery of a New Class of Benzylpiperidine Derivatives | 1-gen-2022 | Bononi, Giulia; Di Stefano, Miriana; Poli, Giulio; Ortore, Gabriella; Meier, Philip; Masetto, Francesca; Caligiuri, Isabella; Rizzolio, Flavio; Macchia, Marco; Chicca, Andrea; Avan, Amir; Giovannetti, Elisa; Vagaggini, Chiara; Brai, Annalaura; Dreassi, Elena; Valoti, Massimo; Minutolo, Filippo; Granchi, Carlotta; Gertsch, Jürg; Tuccinardi, Tiziano | |
| Synthesis and Evaluation of Monoaryl Derivatives as Transthyretin Fibril Formation Inhibitors | 1-gen-2022 | Ciccone, Lidia; Nencetti, Susanna; Camodeca, Caterina; Ortore, Gabriella; Cuffaro, Doretta; Socci, Simone; Orlandini, Elisabetta | |
| Virtual screening and crystallographic studies reveal an unexpected γ-lactone derivative active against MptpB as a potential antitubercular agent | 1-gen-2022 | Cazzaniga, G.; Mori, M.; Meneghetti, F.; Chiarelli, L. R.; Stelitano, G.; Caligiuri, I.; Rizzolio, F.; Ciceri, S.; Poli, G.; Staver, D.; Ortore, G.; Tuccinardi, T.; Villa, S. | |
| Diphenyl-methane based thyromimetic inhibitors for transthyretin amyloidosis | 1-gen-2021 | Kim, B.; Ko, Y. H.; Runfola, M.; Rapposelli, S.; Ortore, G.; Chiellini, G.; Kim, J. H. | |
| Focus on Human Monoamine Transporter Selectivity. New Human DAT and NET Models, Experimental Validation, and SERT Affinity Exploration | 1-gen-2020 | Ortore, G.; Orlandini, E.; Betti, L.; Giannaccini, G.; Mazzoni, M. R.; Camodeca, C.; Nencetti, S. | |
| Identification of histone deacetylase inhibitors with (arylidene)aminoxy scaffold active in uveal melanoma cell lines | 1-gen-2020 | Nencetti, S.; Cuffaro, D.; Nuti, E.; Ciccone, L.; Rossello, A.; Fabbi, M.; Ballante, F.; Ortore, G.; Carbotti, G.; Campelli, F.; Banti, I.; Gangemi, R.; Marshall, G. R.; Orlandini, E. | |
| Discovery of Novel Adenosine Receptor Antagonists through a Combined Structure- and Ligand-Based Approach Followed by Molecular Dynamics Investigation of Ligand Binding Mode | 1-gen-2018 | Lagarias, Panagiotis; Vrontaki, Eleni; Lambrinidis, George; Stamatis, Dimitrios; Convertino, Marino; Ortore, Gabriella; Mavromoustakos, Thomas; Klotz, Karl-Norbert; Kolocouris, Antonios | |
| Identification of Transthyretin Fibril Formation Inhibitors Using Structure-Based Virtual Screening | 1-gen-2017 | Ortore, GABRIELLA MARIA PIA; Martinelli, Adriano | |
| A STRUCTURE-BASED VIRTUAL SCREENING TO IDENTIFY NEW SCAFFOLDS FOR TRANSTHYRETIN FIBRIL FORMATION INHIBITORS | 1-gen-2016 | Ortore, G.; Martinelli, A. | |
| A Virtual Screening Study for Lactate Dehydrogenase 5 Inhibitors by using a Pharmacophore-Based Approach | 1-gen-2016 | Tuccinardi, Tiziano; Poli, Giulio; Corchia, Isacco; Granchi, Carlotta; Lapillo, Margherita; Macchia, Marco; Minutolo, Filippo; Ortore, GABRIELLA MARIA PIA; Martinelli, Adriano | |
| Exploring the binding of quercetin-3-O-metabolites with transthyretin | 1-gen-2016 | Ortore, GABRIELLA MARIA PIA; Ciccone, Lidia; Orlandini, Elisabetta; Stura, E.; Braca, Alessandra; Rossello, Armando; Nencetti, Susanna | |
| Targeting Different Transthyretin Binding Sites with Unusual Natural Compounds | 1-gen-2016 | Ortore, GABRIELLA MARIA PIA; Orlandini, Elisabetta; Braca, Alessandra; Ciccone, Lidia; Rossello, Armando; Martinelli, Adriano; Nencetti, Susanna |