The aim of this study was to detect the variations of Carnosine (Carn) and l-Histidine (l-Hist) concentrations in horse blood plasma as a potential indicator of muscle status during 2 treadmill standardised exercise test (SET) executed at 48 hours one to the other. The concentrations of both molecules increased during all SET; l-Hist concentrations were alwayshigher than Carn ones. Significant increases were found between the values of Carn and of l-Hist during the second SET and in the first versus the second SET (p<0.05) and Carn during thefirst SET (p<0.005). A positive correlation was found in each horse between Carn and l-Hist values (p<0.05). The higher basal values observed during the second SET could be due to the absence in plasma of carnosinase and/or to subclinical muscle damages in untrained horse. Plasma concentrations of these molecules can be useful as clinical indicators of muscle damageand could be utilized to plan SET.
Plasmatic levels of carnosine and l-histidine in horses under treadmill standardised exercise
DUCCI, MICHELE;BARAGLI, PAOLO;GAZZANO, ANGELO;SIGHIERI, CLAUDIO
2007-01-01
Abstract
The aim of this study was to detect the variations of Carnosine (Carn) and l-Histidine (l-Hist) concentrations in horse blood plasma as a potential indicator of muscle status during 2 treadmill standardised exercise test (SET) executed at 48 hours one to the other. The concentrations of both molecules increased during all SET; l-Hist concentrations were alwayshigher than Carn ones. Significant increases were found between the values of Carn and of l-Hist during the second SET and in the first versus the second SET (p<0.05) and Carn during thefirst SET (p<0.005). A positive correlation was found in each horse between Carn and l-Hist values (p<0.05). The higher basal values observed during the second SET could be due to the absence in plasma of carnosinase and/or to subclinical muscle damages in untrained horse. Plasma concentrations of these molecules can be useful as clinical indicators of muscle damageand could be utilized to plan SET.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
