Brugada Syndrome is a form of idiopathic ventricular fibrillation, to date there is no definitive theory about how ventricular fibrillation is initiated or its substrate. Starting from the clinical observation that cardiac episodes are more frequent at rest, we developed a model in order to study the effect of cardiac frequency on reentrant activity. Our results suggest that the combination of arrhythmic substrate and cardiac frequency has a role in the insurgence of cardiac arrhythmia.
Low cardiac frequency associated with higher number of extrasistoles in a computational model of Brugada Syndrome
Biasi, Niccolo;Tognetti, Alessandro
2022-01-01
Abstract
Brugada Syndrome is a form of idiopathic ventricular fibrillation, to date there is no definitive theory about how ventricular fibrillation is initiated or its substrate. Starting from the clinical observation that cardiac episodes are more frequent at rest, we developed a model in order to study the effect of cardiac frequency on reentrant activity. Our results suggest that the combination of arrhythmic substrate and cardiac frequency has a role in the insurgence of cardiac arrhythmia.File in questo prodotto:
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