PURPOSE To assess the evolution of medium size and diminutive polyps on follow-up by CT colonography (CTC). METHOD AND MATERIALS Among 1057 CTC performed in a 3 years period, out of these, 189 (18%) were classified as C-RADS2 and were suggested to repeat CTC within 3 years. At the time of this report, twenty out of 189 (10%) patients have been followed-up with low dose prone and supine CTC. In total thirty-two colonic polyps (22 sized less than 6mm and 10 sized between 6 and 10mm have been analysed. Polyp size was measured by axial and multiplanar reconstructions (MPR) in prone and supine acquisitions. Comparison between size at baseline and follow-up CTC was made on the same view and expressed as mean ± standard deviation. RESULTS Polyps size increased at follow-up compared with baseline CTC examination in 11/32 cases (34.4%), 10 of which were sized less than 6mm (10/22, 45.4%). Overall polyp size was not significantly different at baseline and follow-up (4.14 ± 4.91mm vs 4.52 ± 4.73mm), while size of polyps sized less than 6mm was significantly higher at follow-up (3.20 ± 3.25mm vs 1.52 ± 2.20mm, respectively; p=0.0188, Friedman rank test). Size of polyps in the 6-10mm category was not significantly different at baseline and follow-up (7.71 ± 1.25mm vs 6.14 ± 4.34mm, p=0.25). CONCLUSION Polyps size increased in a small percentage of cases, but the vast majority were diminutive lesions. No statistically significant changes occurred in the medium size polyps. This preliminary results suggest that polyps follow-up in a maximum 3 years period do not increase the risk of developing colorectal cancer. CLINICAL RELEVANCE/APPLICATION These preliminary results supports the rationale of CRADS 2 recommendations about follow-up of medium size polyps.

CT COLONOGRAPHY: 1-3 YEARS FOLLOW-UP OF MEDIUM SIZE (CRADS 2) AND DIMINUTIVE POLYPS. PRELIMINARY RESULTS

NERI, EMANUELE;
2009-01-01

Abstract

PURPOSE To assess the evolution of medium size and diminutive polyps on follow-up by CT colonography (CTC). METHOD AND MATERIALS Among 1057 CTC performed in a 3 years period, out of these, 189 (18%) were classified as C-RADS2 and were suggested to repeat CTC within 3 years. At the time of this report, twenty out of 189 (10%) patients have been followed-up with low dose prone and supine CTC. In total thirty-two colonic polyps (22 sized less than 6mm and 10 sized between 6 and 10mm have been analysed. Polyp size was measured by axial and multiplanar reconstructions (MPR) in prone and supine acquisitions. Comparison between size at baseline and follow-up CTC was made on the same view and expressed as mean ± standard deviation. RESULTS Polyps size increased at follow-up compared with baseline CTC examination in 11/32 cases (34.4%), 10 of which were sized less than 6mm (10/22, 45.4%). Overall polyp size was not significantly different at baseline and follow-up (4.14 ± 4.91mm vs 4.52 ± 4.73mm), while size of polyps sized less than 6mm was significantly higher at follow-up (3.20 ± 3.25mm vs 1.52 ± 2.20mm, respectively; p=0.0188, Friedman rank test). Size of polyps in the 6-10mm category was not significantly different at baseline and follow-up (7.71 ± 1.25mm vs 6.14 ± 4.34mm, p=0.25). CONCLUSION Polyps size increased in a small percentage of cases, but the vast majority were diminutive lesions. No statistically significant changes occurred in the medium size polyps. This preliminary results suggest that polyps follow-up in a maximum 3 years period do not increase the risk of developing colorectal cancer. CLINICAL RELEVANCE/APPLICATION These preliminary results supports the rationale of CRADS 2 recommendations about follow-up of medium size polyps.
2009
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/132403
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