We address some problems arising in the analysis and representation of genomic data. The thesis is divided in two parts. Part~I contains studies on large scale mutations of genomes with particular attention to gene duplications. We prove some results on genomic syntenic distance, and investigate some properties of families of paralogous genes. These latter can also form a ground for genome comparisons. Part~II contains some studies on motif extraction which role in molecular biology is crucial for building genome maps and for many other applications at structures and similarities in biological sequences.
Segment-based distances and similarities in genomic sequences
PISANTI, NADIA
2002-01-01
Abstract
We address some problems arising in the analysis and representation of genomic data. The thesis is divided in two parts. Part~I contains studies on large scale mutations of genomes with particular attention to gene duplications. We prove some results on genomic syntenic distance, and investigate some properties of families of paralogous genes. These latter can also form a ground for genome comparisons. Part~II contains some studies on motif extraction which role in molecular biology is crucial for building genome maps and for many other applications at structures and similarities in biological sequences.File in questo prodotto:
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