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A new standardization of the Bells Test: an Italian multi-center normative study

Objective: The Bells Test is a cancellation task that is widely used for the diagnosis of unilateral spatial neglect (USN). With the aim of fostering more reliable use of this instrument, we set out to develop new norms adjusted for the possible influence of age, gender and education. We worked on the original version of the test. Method: Normative data were collected from 401 healthy participants aged between 20 and 80 years. Individual factors that could affect performance (i.e. gender, ag...

Targeting STATs in neuroinflammation: the Road Less Traveled!

JAK/STAT transduction pathway is a highly conserved pathway implicated in regulating cellular proliferation, differentiation, survival and apoptosis. Dysregulation of this pathway is involved in the onset of autoimmune, haematological, oncological, metabolic and neurological diseases. Over the last few years, the research of anti-neuroinflammatory agents has gained considerable attention. The ability to diminish the STAT-induced transcription of inflammatory genes is documented for both natur...

Internet of Things for Enabling Smart Environments: a Technology-Centric Perspective

The Internet of Things (IoT) is a computing paradigm whereby everyday life objects are augmented with computational and wireless communication capabilities, typically through the incorporation of resource-constrained devices including sensors and actuators, which enable their connection to the Internet. The IoT is seen as the key ingredient for the development of smart environments. Nevertheless, the current IoT ecosystem offers many alternative communication solutions with diverse perfor...

Geographical Analysis of Agro-Environmental Measures for Reduction of Chemical Inputs in Tuscany

The agro-environmental policies included in rural development plans are getting increasing importance in European Community strategies. These policies represent the meeting point between demand and supply of positive externalities. The difficulty of assessing real envi- ronmental efficiency is one of the elements characterizing agro-environmental measures. This difficulty is related to the identification of suitable parameters for evaluating farms according to their impact on the territory. T...

A methodology for simulation-based, multiobjective gear design optimization

Design optimization of geared transmissions has become more of a necessity than ever before. Typically, conflicting design goals must be concurrently achieved. The difficulty of such a multiobjective design optimization problem is exacerbated by the fact that modern design practices rely on increasingly sophisticated, computationally-expensive simulation tools for tooth contact analysis. Their intrinsic nonlinearities add complexity to the problem, hampering gear designers’ efforts to obtain ...

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