The Basilica of Saint Domenico Maggiore in Naples holds the tombs of some Aragonese kings and other nobles of the 16th century Spanish court. Among these burials, the natural, intact mummy of Ferdinando Orsini, 5thDuke of Gravina, dead in 1549 at age of 50-55 years, was studied. Autopsy revealed a large osteolithic lesion of the frontal and right nasal bones, covered by a swab. Histological and immuno-histochemical study showed solid tumor with dark margins, composed of epithelial-like cells with hyperchromatic nuclei. These aspects strongly suggest the diagnosis of an advanced skin malignant tumor, the basal cell carcinoma, also known as ‘ulcus rodens’. This case is one of the four malignant soft tissue tumors at present diagnosed in paleopathology.
Il tumore di Ferdinando Orsini, duca di Gravina di Puglia (+1549)
GAETA, RAFFAELE;FORNACIARI, GINO
2015-01-01
Abstract
The Basilica of Saint Domenico Maggiore in Naples holds the tombs of some Aragonese kings and other nobles of the 16th century Spanish court. Among these burials, the natural, intact mummy of Ferdinando Orsini, 5thDuke of Gravina, dead in 1549 at age of 50-55 years, was studied. Autopsy revealed a large osteolithic lesion of the frontal and right nasal bones, covered by a swab. Histological and immuno-histochemical study showed solid tumor with dark margins, composed of epithelial-like cells with hyperchromatic nuclei. These aspects strongly suggest the diagnosis of an advanced skin malignant tumor, the basal cell carcinoma, also known as ‘ulcus rodens’. This case is one of the four malignant soft tissue tumors at present diagnosed in paleopathology.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
