Summary - This paper illustrates the difficulties of accurately assessing the coagulation profile due to the complexity of this system, which is strictly related to inflammatory conditions. Moreover, the classical interpretation of the blood coagulation cascade has been reviewed, and some new highlights pointed out. Currently, several tests are available to explore primary or secondary haemostasis as well as fibrinolysis. The decision to use a preliminary panel of tests readily accessible to veterinarians in practice is worthy. Tests included in the preliminary panel should give a basic interpretation in the several steps of coagulation with good sensitivity and specificity. Then, depending on the results obtained, more detailed assays could be used in order to characterize the defect or the exact deficiency in haemostasis.
Updates on coagulation testing
LUBAS, GEORGE;
2004-01-01
Abstract
Summary - This paper illustrates the difficulties of accurately assessing the coagulation profile due to the complexity of this system, which is strictly related to inflammatory conditions. Moreover, the classical interpretation of the blood coagulation cascade has been reviewed, and some new highlights pointed out. Currently, several tests are available to explore primary or secondary haemostasis as well as fibrinolysis. The decision to use a preliminary panel of tests readily accessible to veterinarians in practice is worthy. Tests included in the preliminary panel should give a basic interpretation in the several steps of coagulation with good sensitivity and specificity. Then, depending on the results obtained, more detailed assays could be used in order to characterize the defect or the exact deficiency in haemostasis.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
