Sfoglia per Autore
Continued exploration of 1,2,4-oxadiazole periphery for carbonic anhydrase-targeting primary arene sulfonamides: Discovery of subnanomolar inhibitors of membrane-bound hCA IX isoform that selectively kill cancer cells in hypoxic environment
2019-01-01 Krasavin, Mikhail; Shetnev, Anton; Sharonova, Tatyana; Baykov, Sergey; Kalinin, Stanislav; Nocentini, Alessio; Sharoyko, Vladimir; Poli, Giulio; Tuccinardi, Tiziano; Presnukhina, Sofia; Tennikova, Tatiana B.; Supuran, Claudiu T.
New insight into structure-activity of furan-based salicylate synthase (MbtI) inhibitors as potential antitubercular agents
2019-01-01 Chiarelli, L. R.; Mori, M.; Beretta, G.; Gelain, A.; Pini, E.; Sammartino, J. C.; Stelitano, G.; Barlocco, D.; Costantino, L.; Lapillo, M.; Poli, G.; Caligiuri, I.; Rizzolio, F.; Bellinzoni, M.; Tuccinardi, T.; Villa, S.; Meneghetti, F.
N-aryl-N’-ureido-O-sulfamates: Potent and selective inhibitors of the human Carbonic Anhydrase VII isoform with neuropathic pain relieving properties
2019-01-01 Bozdag, M.; Poli, G.; Angeli, A.; Lucarini, E.; Tuccinardi, T.; Di Cesare Mannelli, L.; Selleri, S.; Ghelardini, C.; Winum, J. -Y.; Carta, F.; Supuran, C. T.
The Extra-Virgin Olive Oil Polyphenols Oleocanthal and Oleacein Counteract Inflammation-Related Gene and miRNA Expression in Adipocytes by Attenuating NF-κB Activation
2019-01-01 Carpi, Sara; Scoditti, Egeria; Massaro, Marika; Polini, Beatrice; Manera, Clementina; Digiacomo, Maria; Esposito Salsano, Jasmine; Poli, Giulio; Tuccinardi, Tiziano; Doccini, Stefano; Santorelli, Filippo Maria; Carluccio, Maria Annunziata; Macchia, Marco; Wabitsch, Martin; De Caterina, Raffaele; Nieri, Paola
Three-dimensional interactions analysis of the anticancer target c-src kinase with its inhibitors
2020-01-01 Jha, V.; Macchia, M.; Tuccinardi, T.; Poli, G.
Application of MM-PBSA methods in virtual screening
2020-01-01 Poli, G.; Granchi, C.; Rizzolio, F.; Tuccinardi, T.
Aldose reductase differential inhibitors in green tea
2020-01-01 Balestri, F.; Poli, G.; Pineschi, C.; Moschini, R.; Cappiello, M.; Mura, U.; Tuccinardi, T.; Corso, A. D.
Consensus Docking in Drug Discovery
2020-01-01 Poli, Giulio; Tuccinardi, Tiziano
Modification on the 1,2-dihydro-2-oxo-pyridine-3-carboxamide core to obtain multi-target modulators of endocannabinoid system
2020-01-01 Gado, F.; Arena, C.; Fauci, C. L.; Reynoso-Moreno, I.; Bertini, S.; Digiacomo, M.; Meini, S.; Poli, G.; Macchia, M.; Tuccinardi, T.; Gertsch, J.; Chicca, A.; Manera, C.
Shedding X-ray Light on the Role of Magnesium in the Activity of Mycobacterium tuberculosis Salicylate Synthase (MbtI) for Drug Design
2020-01-01 Mori, M.; Stelitano, G.; Gelain, A.; Pini, E.; Chiarelli, L. R.; Sammartino, J. C.; Poli, G.; Tuccinardi, T.; Beretta, G.; Porta, A.; Bellinzoni, M.; Villa, S.; Meneghetti, F.
N-aryl-N′-ureido-O-sulfamates as potent and selective inhibitors of hCA VB over hCA VA: Deciphering the binding mode of new potential agents in mitochondrial dysfunctions
2020-01-01 Poli, G.; Bozdag, M.; Berrino, E.; Angeli, A.; Tuccinardi, T.; Carta, F.; Supuran, C. T.
Development of a cheminformatics platform for selectivity analyses of carbonic anhydrase inhibitors
2020-01-01 Poli, G.; Galati, S.; Martinelli, A.; Supuran, C. T.; Tuccinardi, T.
Antibacterial and ATP Synthesis Modulating Compounds from Salvia tingitana
2020-01-01 Bisio, A.; Schito, A. M.; Pedrelli, F.; Danton, O.; Reinhardt, J. K.; Poli, G.; Tuccinardi, T.; Burgi, T.; De Riccardis, F.; Giacomini, M.; Calzia, D.; Panfoli, I.; Schito, G. C.; Hamburger, M.; De Tommasi, N.
The endocannabinoid system dual-target ligand N-cycloheptyl-1,2-dihydro-5-bromo-1-(4-fluorobenzyl)-6-methyl-2-oxo-pyridine-3-carboxamide improves disease severity in a mouse model of multiple sclerosis
2020-01-01 Arena, C.; Gado, F.; Di Cesare Mannelli, L.; Cervetto, C.; Carpi, S.; Reynoso-Moreno, I.; Polini, B.; Vallini, E.; Chicca, S.; Lucarini, E.; Bertini, S.; D'Andrea, F.; Digiacomo, M.; Poli, G.; Tuccinardi, T.; Macchia, M.; Gertsch, J.; Marcoli, M.; Nieri, P.; Ghelardini, C.; Chicca, A.; Manera, C.
1,3-Dipolar Cycloaddition, HPLC Enantioseparation, and Docking Studies of Saccharin/Isoxazole and Saccharin/Isoxazoline Derivatives as Selective Carbonic Anhydrase IX and XII Inhibitors
2020-01-01 D'Ascenzio, M.; Secci, D.; Carradori, S.; Zara, S.; Guglielmi, P.; Cirilli, R.; Pierini, M.; Poli, G.; Tuccinardi, T.; Angeli, A.; Supuran, C. T.
Nuovi inibitori reversibili della monoacilglicerolo lipasi (MAGL) quali potenziali agenti antitumorali, antiinfiammatori e neuroprotettivi.
2020-01-01 Granchi, Carlotta; Bononi, Giulia; Macchia, Marco; Minutolo, Filippo; Poli, Giulio; Scalabrini, Diana; Tuccinardi, Tiziano; Rizzolio, Flavio; Giordano, Antonio
Discovery of monoacylglycerol lipase (MAGL) inhibitors based on a pharmacophore-guided virtual screening study
2021-01-01 Jha, V.; Biagi, M.; Spinelli, V.; Di Stefano, M. D.; Macchia, M.; Minutolo, F.; Granchi, C.; Poli, G.; Tuccinardi, T.
Recent advances in in silico target fishing
2021-01-01 Galati, S.; Di Stefano, M.; Martinelli, E.; Poli, G.; Tuccinardi, T.
An updated patent review of monoacylglycerol lipase (MAGL) inhibitors (2018-present)
2021-01-01 Bononi, G.; Poli, G.; Rizzolio, F.; Tuccinardi, T.; Macchia, M.; Minutolo, F.; Granchi, C.
Discovery of a new ATP-citrate lyase (ACLY) inhibitor identified by a pharmacophore-based virtual screening study
2021-01-01 Jha, V.; Galati, S.; Volpi, V.; Ciccone, L.; Minutolo, F.; Rizzolio, F.; Granchi, C.; Poli, G.; Tuccinardi, T.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Continued exploration of 1,2,4-oxadiazole periphery for carbonic anhydrase-targeting primary arene sulfonamides: Discovery of subnanomolar inhibitors of membrane-bound hCA IX isoform that selectively kill cancer cells in hypoxic environment | 1-gen-2019 | Krasavin, Mikhail; Shetnev, Anton; Sharonova, Tatyana; Baykov, Sergey; Kalinin, Stanislav; Nocentini, Alessio; Sharoyko, Vladimir; Poli, Giulio; Tuccinardi, Tiziano; Presnukhina, Sofia; Tennikova, Tatiana B.; Supuran, Claudiu T. | |
| New insight into structure-activity of furan-based salicylate synthase (MbtI) inhibitors as potential antitubercular agents | 1-gen-2019 | Chiarelli, L. R.; Mori, M.; Beretta, G.; Gelain, A.; Pini, E.; Sammartino, J. C.; Stelitano, G.; Barlocco, D.; Costantino, L.; Lapillo, M.; Poli, G.; Caligiuri, I.; Rizzolio, F.; Bellinzoni, M.; Tuccinardi, T.; Villa, S.; Meneghetti, F. | |
| N-aryl-N’-ureido-O-sulfamates: Potent and selective inhibitors of the human Carbonic Anhydrase VII isoform with neuropathic pain relieving properties | 1-gen-2019 | Bozdag, M.; Poli, G.; Angeli, A.; Lucarini, E.; Tuccinardi, T.; Di Cesare Mannelli, L.; Selleri, S.; Ghelardini, C.; Winum, J. -Y.; Carta, F.; Supuran, C. T. | |
| The Extra-Virgin Olive Oil Polyphenols Oleocanthal and Oleacein Counteract Inflammation-Related Gene and miRNA Expression in Adipocytes by Attenuating NF-κB Activation | 1-gen-2019 | Carpi, Sara; Scoditti, Egeria; Massaro, Marika; Polini, Beatrice; Manera, Clementina; Digiacomo, Maria; Esposito Salsano, Jasmine; Poli, Giulio; Tuccinardi, Tiziano; Doccini, Stefano; Santorelli, Filippo Maria; Carluccio, Maria Annunziata; Macchia, Marco; Wabitsch, Martin; De Caterina, Raffaele; Nieri, Paola | |
| Three-dimensional interactions analysis of the anticancer target c-src kinase with its inhibitors | 1-gen-2020 | Jha, V.; Macchia, M.; Tuccinardi, T.; Poli, G. | |
| Application of MM-PBSA methods in virtual screening | 1-gen-2020 | Poli, G.; Granchi, C.; Rizzolio, F.; Tuccinardi, T. | |
| Aldose reductase differential inhibitors in green tea | 1-gen-2020 | Balestri, F.; Poli, G.; Pineschi, C.; Moschini, R.; Cappiello, M.; Mura, U.; Tuccinardi, T.; Corso, A. D. | |
| Consensus Docking in Drug Discovery | 1-gen-2020 | Poli, Giulio; Tuccinardi, Tiziano | |
| Modification on the 1,2-dihydro-2-oxo-pyridine-3-carboxamide core to obtain multi-target modulators of endocannabinoid system | 1-gen-2020 | Gado, F.; Arena, C.; Fauci, C. L.; Reynoso-Moreno, I.; Bertini, S.; Digiacomo, M.; Meini, S.; Poli, G.; Macchia, M.; Tuccinardi, T.; Gertsch, J.; Chicca, A.; Manera, C. | |
| Shedding X-ray Light on the Role of Magnesium in the Activity of Mycobacterium tuberculosis Salicylate Synthase (MbtI) for Drug Design | 1-gen-2020 | Mori, M.; Stelitano, G.; Gelain, A.; Pini, E.; Chiarelli, L. R.; Sammartino, J. C.; Poli, G.; Tuccinardi, T.; Beretta, G.; Porta, A.; Bellinzoni, M.; Villa, S.; Meneghetti, F. | |
| N-aryl-N′-ureido-O-sulfamates as potent and selective inhibitors of hCA VB over hCA VA: Deciphering the binding mode of new potential agents in mitochondrial dysfunctions | 1-gen-2020 | Poli, G.; Bozdag, M.; Berrino, E.; Angeli, A.; Tuccinardi, T.; Carta, F.; Supuran, C. T. | |
| Development of a cheminformatics platform for selectivity analyses of carbonic anhydrase inhibitors | 1-gen-2020 | Poli, G.; Galati, S.; Martinelli, A.; Supuran, C. T.; Tuccinardi, T. | |
| Antibacterial and ATP Synthesis Modulating Compounds from Salvia tingitana | 1-gen-2020 | Bisio, A.; Schito, A. M.; Pedrelli, F.; Danton, O.; Reinhardt, J. K.; Poli, G.; Tuccinardi, T.; Burgi, T.; De Riccardis, F.; Giacomini, M.; Calzia, D.; Panfoli, I.; Schito, G. C.; Hamburger, M.; De Tommasi, N. | |
| The endocannabinoid system dual-target ligand N-cycloheptyl-1,2-dihydro-5-bromo-1-(4-fluorobenzyl)-6-methyl-2-oxo-pyridine-3-carboxamide improves disease severity in a mouse model of multiple sclerosis | 1-gen-2020 | Arena, C.; Gado, F.; Di Cesare Mannelli, L.; Cervetto, C.; Carpi, S.; Reynoso-Moreno, I.; Polini, B.; Vallini, E.; Chicca, S.; Lucarini, E.; Bertini, S.; D'Andrea, F.; Digiacomo, M.; Poli, G.; Tuccinardi, T.; Macchia, M.; Gertsch, J.; Marcoli, M.; Nieri, P.; Ghelardini, C.; Chicca, A.; Manera, C. | |
| 1,3-Dipolar Cycloaddition, HPLC Enantioseparation, and Docking Studies of Saccharin/Isoxazole and Saccharin/Isoxazoline Derivatives as Selective Carbonic Anhydrase IX and XII Inhibitors | 1-gen-2020 | D'Ascenzio, M.; Secci, D.; Carradori, S.; Zara, S.; Guglielmi, P.; Cirilli, R.; Pierini, M.; Poli, G.; Tuccinardi, T.; Angeli, A.; Supuran, C. T. | |
| Nuovi inibitori reversibili della monoacilglicerolo lipasi (MAGL) quali potenziali agenti antitumorali, antiinfiammatori e neuroprotettivi. | 1-gen-2020 | Granchi, Carlotta; Bononi, Giulia; Macchia, Marco; Minutolo, Filippo; Poli, Giulio; Scalabrini, Diana; Tuccinardi, Tiziano; Rizzolio, Flavio; Giordano, Antonio | |
| Discovery of monoacylglycerol lipase (MAGL) inhibitors based on a pharmacophore-guided virtual screening study | 1-gen-2021 | Jha, V.; Biagi, M.; Spinelli, V.; Di Stefano, M. D.; Macchia, M.; Minutolo, F.; Granchi, C.; Poli, G.; Tuccinardi, T. | |
| Recent advances in in silico target fishing | 1-gen-2021 | Galati, S.; Di Stefano, M.; Martinelli, E.; Poli, G.; Tuccinardi, T. | |
| An updated patent review of monoacylglycerol lipase (MAGL) inhibitors (2018-present) | 1-gen-2021 | Bononi, G.; Poli, G.; Rizzolio, F.; Tuccinardi, T.; Macchia, M.; Minutolo, F.; Granchi, C. | |
| Discovery of a new ATP-citrate lyase (ACLY) inhibitor identified by a pharmacophore-based virtual screening study | 1-gen-2021 | Jha, V.; Galati, S.; Volpi, V.; Ciccone, L.; Minutolo, F.; Rizzolio, F.; Granchi, C.; Poli, G.; Tuccinardi, T. |
Legenda icone
- file ad accesso aperto
- file disponibili sulla rete interna
- file disponibili agli utenti autorizzati
- file disponibili solo agli amministratori
- file sotto embargo
- nessun file disponibile