Sfoglia per Autore
Discovery and development of novel salicylate synthase (MbtI) furanic inhibitors as antitubercular agents
2018-01-01 Chiarelli, Laurent R; Mori, Matteo; Barlocco, Daniela; Beretta, Giangiacomo; Gelain, Arianna; Pini, Elena; Porcino, Marianna; Mori, Giorgia; Stelitano, Giovanni; Costantino, Luca; Lapillo, Margherita; Bonanni, Davide; Poli, Giulio; Tuccinardi, Tiziano; Villa, Stefania; Meneghetti, Fiorella
Rhodanine derivatives as potent anti-HIV and anti-HSV microbicides
2018-01-01 Tintori, Cristina; Iovenitti, Giulia; Ceresola, Elisa Rita; Ferrarese, Roberto; Zamperini, Claudio; Brai, Annalaura; Poli, Giulio; Dreassi, Elena; Cagno, Valeria; Lembo, David; Canducci, Filippo; Botta, Maurizio
Conformational sampling of small molecules with iCon: Performance assessment in comparison with OMEGA
2018-01-01 Poli, Giulio; Seidel, Thomas; Langer, Thierry
Binding investigation and preliminary optimisation of the 3-amino-1,2,4-triazin-5(2H)-one core for the development of new Fyn inhibitors
2018-01-01 Poli, Giulio; Lapillo, Margherita; Granchi, Carlotta; Caciolla, Jessica; Mouawad, Nayla; Caligiuri, Isabella; Rizzolio, Flavio; Langer, Thierry; Minutolo, Filippo; Tuccinardi, Tiziano
Discovery of long-chain salicylketoxime derivatives as monoacylglycerol lipase (MAGL) inhibitors
2018-01-01 Bononi, Giulia; Granchi, Carlotta; Lapillo, Margherita; Giannotti, Massimiliano; Nieri, Daniela; Fortunato, Serena; Boustani, Maguie El; Caligiuri, Isabella; Poli, Giulio; Carlson, Kathryn E.; Kim, Sung Hoon; Macchia, Marco; Martinelli, Adriano; Rizzolio, Flavio; Chicca, Andrea; Katzenellenbogen, John A.; Minutolo, Filippo; Tuccinardi, Tiziano
Novel broad spectrum virucidal molecules against enveloped viruses
2018-01-01 Cagno, Valeria; Tintori, Cristina; Civra, Andrea; Cavalli, Roberta; Tiberi, Marika; Botta, Lorenzo; Brai, Annalaura; Poli, Giulio; Tapparel, Caroline; Lembo, David; Botta, Maurizio
Development of a Fingerprint-Based Scoring Function for the Prediction of the Binding Mode of Carbonic Anhydrase II Inhibitors
2018-01-01 Poli, Giulio; Jha, Vibhu; Martinelli, Adriano; Supuran, Claudiu T; Tuccinardi, Tiziano
New insight into structure-activity of furan-based salicylate synthase (MbtI) inhibitors as potential antitubercular agents
2019-01-01 Chiarelli, L. R.; Mori, M.; Beretta, G.; Gelain, A.; Pini, E.; Sammartino, J. C.; Stelitano, G.; Barlocco, D.; Costantino, L.; Lapillo, M.; Poli, G.; Caligiuri, I.; Rizzolio, F.; Bellinzoni, M.; Tuccinardi, T.; Villa, S.; Meneghetti, F.
The acyl-glucuronide metabolite of ibuprofen has analgesic and anti-inflammatory effects via the TRPA1 channel
2019-01-01 De Logu, F.; Li Puma, S.; Landini, L.; Tuccinardi, T.; Poli, G.; Preti, D.; De Siena, G.; Patacchini, R.; Tsagareli, M. G.; Geppetti, P.; Nassini, R.
Pyridazinone-substituted benzenesulfonamides display potent inhibition of membrane-bound human carbonic anhydrase IX and promising antiproliferative activity against cancer cell lines
2019-01-01 Krasavin, M.; Shetnev, A.; Baykov, S.; Kalinin, S.; Nocentini, A.; Sharoyko, V.; Poli, G.; Tuccinardi, T.; Korsakov, M.; Tennikova, T. B.; Supuran, C. T.
First-of-its-kind STARD 3 Inhibitor: In Silico Identification and Biological Evaluation as Anticancer Agent
2019-01-01 Lapillo, M.; Salis, B.; Palazzolo, S.; Poli, G.; Granchi, C.; Minutolo, F.; Rotondo, R.; Caligiuri, I.; Canzonieri, V.; Tuccinardi, T.; Rizzolio, F.
Continued exploration of 1,2,4-oxadiazole periphery for carbonic anhydrase-targeting primary arene sulfonamides: Discovery of subnanomolar inhibitors of membrane-bound hCA IX isoform that selectively kill cancer cells in hypoxic environment
2019-01-01 Krasavin, Mikhail; Shetnev, Anton; Sharonova, Tatyana; Baykov, Sergey; Kalinin, Stanislav; Nocentini, Alessio; Sharoyko, Vladimir; Poli, Giulio; Tuccinardi, Tiziano; Presnukhina, Sofia; Tennikova, Tatiana B.; Supuran, Claudiu T.
Design, synthesis, docking studies and monoamine oxidase inhibition of a small library of 1-acetyl- and 1-thiocarbamoyl-3,5-diphenyl-4,5-dihydro-(1h)-pyrazoles
2019-01-01 Guglielmi, P.; Carradori, S.; Poli, G.; Secci, D.; Cirilli, R.; Rotondi, G.; Chimenti, P.; Petzer, A.; Petzer, J. P.
Synthesis and Biological Evaluation of New Glycoconjugated LDH Inhibitors as Anticancer Agents
2019-01-01 D'Andrea, Felicia; Giulia, Vagelli; Granchi, Carlotta; Guazzelli, Lorenzo; Tuccinardi, Tiziano; Poli, Giulio; Iacopini, Dalila; Minutolo, Filippo; DI BUSSOLO, Valeria
N-aryl-N’-ureido-O-sulfamates: Potent and selective inhibitors of the human Carbonic Anhydrase VII isoform with neuropathic pain relieving properties
2019-01-01 Bozdag, M.; Poli, G.; Angeli, A.; Lucarini, E.; Tuccinardi, T.; Di Cesare Mannelli, L.; Selleri, S.; Ghelardini, C.; Winum, J. -Y.; Carta, F.; Supuran, C. T.
Virtual screening identifies a PIN1 inhibitor with possible antiovarian cancer effects
2019-01-01 Russo Spena, C.; De Stefano, L.; Poli, G.; Granchi, C.; El Boustani, M.; Ecca, F.; Grassi, G.; Grassi, M.; Canzonieri, V.; Giordano, A.; Tuccinardi, T.; Caligiuri, I.; Rizzolio, F.
Rutin as promising drug for the treatment of Parkinson’s disease: an assessment of MAO-B inhibitory potential by docking, molecular dynamics and DFT studies
2019-01-01 Azam, F.; Abodabos, H. S.; Taban, I. M.; Rfieda, A. R.; Mahmood, D.; Anwar, M. J.; Khan, S.; Sizochenko, N.; Poli, G.; Tuccinardi, T.; Ali, H. I.
Computationally driven discovery of phenyl(piperazin-1-yl)methanone derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors
2019-01-01 Poli, Giulio; Lapillo, Margherita; Jha, Vibhu; Mouawad, Nayla; Caligiuri, Isabella; Macchia, Marco; Minutolo, Filippo; Rizzolio, Flavio; Tuccinardi, Tiziano; Granchi, Carlotta
Optimization of a Benzoylpiperidine Class Identifies a Highly Potent and Selective Reversible Monoacylglycerol Lipase (MAGL) Inhibitor
2019-01-01 Granchi, Carlotta; Lapillo, Margherita; Glasmacher, Sandra; Bononi, Giulia; Licari, Cristina; Poli, Giulio; El Boustani, Maguie; Caligiuri, Isabella; Rizzolio, Flavio; Gertsch, Jürg; Macchia, Marco; Minutolo, Filippo; Tuccinardi, Tiziano; Chicca, Andrea
L-DOPA-quinone Mediated Recovery from GIRK Channel Firing Inhibition in Dopaminergic Neurons
2019-01-01 Bizzarri, B. M.; Botta, L.; Aversa, D.; Mercuri, N. B.; Poli, G.; Barbieri, A.; Berretta, N.; Saladino, R.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Discovery and development of novel salicylate synthase (MbtI) furanic inhibitors as antitubercular agents | 1-gen-2018 | Chiarelli, Laurent R; Mori, Matteo; Barlocco, Daniela; Beretta, Giangiacomo; Gelain, Arianna; Pini, Elena; Porcino, Marianna; Mori, Giorgia; Stelitano, Giovanni; Costantino, Luca; Lapillo, Margherita; Bonanni, Davide; Poli, Giulio; Tuccinardi, Tiziano; Villa, Stefania; Meneghetti, Fiorella | |
| Rhodanine derivatives as potent anti-HIV and anti-HSV microbicides | 1-gen-2018 | Tintori, Cristina; Iovenitti, Giulia; Ceresola, Elisa Rita; Ferrarese, Roberto; Zamperini, Claudio; Brai, Annalaura; Poli, Giulio; Dreassi, Elena; Cagno, Valeria; Lembo, David; Canducci, Filippo; Botta, Maurizio | |
| Conformational sampling of small molecules with iCon: Performance assessment in comparison with OMEGA | 1-gen-2018 | Poli, Giulio; Seidel, Thomas; Langer, Thierry | |
| Binding investigation and preliminary optimisation of the 3-amino-1,2,4-triazin-5(2H)-one core for the development of new Fyn inhibitors | 1-gen-2018 | Poli, Giulio; Lapillo, Margherita; Granchi, Carlotta; Caciolla, Jessica; Mouawad, Nayla; Caligiuri, Isabella; Rizzolio, Flavio; Langer, Thierry; Minutolo, Filippo; Tuccinardi, Tiziano | |
| Discovery of long-chain salicylketoxime derivatives as monoacylglycerol lipase (MAGL) inhibitors | 1-gen-2018 | Bononi, Giulia; Granchi, Carlotta; Lapillo, Margherita; Giannotti, Massimiliano; Nieri, Daniela; Fortunato, Serena; Boustani, Maguie El; Caligiuri, Isabella; Poli, Giulio; Carlson, Kathryn E.; Kim, Sung Hoon; Macchia, Marco; Martinelli, Adriano; Rizzolio, Flavio; Chicca, Andrea; Katzenellenbogen, John A.; Minutolo, Filippo; Tuccinardi, Tiziano | |
| Novel broad spectrum virucidal molecules against enveloped viruses | 1-gen-2018 | Cagno, Valeria; Tintori, Cristina; Civra, Andrea; Cavalli, Roberta; Tiberi, Marika; Botta, Lorenzo; Brai, Annalaura; Poli, Giulio; Tapparel, Caroline; Lembo, David; Botta, Maurizio | |
| Development of a Fingerprint-Based Scoring Function for the Prediction of the Binding Mode of Carbonic Anhydrase II Inhibitors | 1-gen-2018 | Poli, Giulio; Jha, Vibhu; Martinelli, Adriano; Supuran, Claudiu T; Tuccinardi, Tiziano | |
| New insight into structure-activity of furan-based salicylate synthase (MbtI) inhibitors as potential antitubercular agents | 1-gen-2019 | Chiarelli, L. R.; Mori, M.; Beretta, G.; Gelain, A.; Pini, E.; Sammartino, J. C.; Stelitano, G.; Barlocco, D.; Costantino, L.; Lapillo, M.; Poli, G.; Caligiuri, I.; Rizzolio, F.; Bellinzoni, M.; Tuccinardi, T.; Villa, S.; Meneghetti, F. | |
| The acyl-glucuronide metabolite of ibuprofen has analgesic and anti-inflammatory effects via the TRPA1 channel | 1-gen-2019 | De Logu, F.; Li Puma, S.; Landini, L.; Tuccinardi, T.; Poli, G.; Preti, D.; De Siena, G.; Patacchini, R.; Tsagareli, M. G.; Geppetti, P.; Nassini, R. | |
| Pyridazinone-substituted benzenesulfonamides display potent inhibition of membrane-bound human carbonic anhydrase IX and promising antiproliferative activity against cancer cell lines | 1-gen-2019 | Krasavin, M.; Shetnev, A.; Baykov, S.; Kalinin, S.; Nocentini, A.; Sharoyko, V.; Poli, G.; Tuccinardi, T.; Korsakov, M.; Tennikova, T. B.; Supuran, C. T. | |
| First-of-its-kind STARD 3 Inhibitor: In Silico Identification and Biological Evaluation as Anticancer Agent | 1-gen-2019 | Lapillo, M.; Salis, B.; Palazzolo, S.; Poli, G.; Granchi, C.; Minutolo, F.; Rotondo, R.; Caligiuri, I.; Canzonieri, V.; Tuccinardi, T.; Rizzolio, F. | |
| Continued exploration of 1,2,4-oxadiazole periphery for carbonic anhydrase-targeting primary arene sulfonamides: Discovery of subnanomolar inhibitors of membrane-bound hCA IX isoform that selectively kill cancer cells in hypoxic environment | 1-gen-2019 | Krasavin, Mikhail; Shetnev, Anton; Sharonova, Tatyana; Baykov, Sergey; Kalinin, Stanislav; Nocentini, Alessio; Sharoyko, Vladimir; Poli, Giulio; Tuccinardi, Tiziano; Presnukhina, Sofia; Tennikova, Tatiana B.; Supuran, Claudiu T. | |
| Design, synthesis, docking studies and monoamine oxidase inhibition of a small library of 1-acetyl- and 1-thiocarbamoyl-3,5-diphenyl-4,5-dihydro-(1h)-pyrazoles | 1-gen-2019 | Guglielmi, P.; Carradori, S.; Poli, G.; Secci, D.; Cirilli, R.; Rotondi, G.; Chimenti, P.; Petzer, A.; Petzer, J. P. | |
| Synthesis and Biological Evaluation of New Glycoconjugated LDH Inhibitors as Anticancer Agents | 1-gen-2019 | D'Andrea, Felicia; Giulia, Vagelli; Granchi, Carlotta; Guazzelli, Lorenzo; Tuccinardi, Tiziano; Poli, Giulio; Iacopini, Dalila; Minutolo, Filippo; DI BUSSOLO, Valeria | |
| N-aryl-N’-ureido-O-sulfamates: Potent and selective inhibitors of the human Carbonic Anhydrase VII isoform with neuropathic pain relieving properties | 1-gen-2019 | Bozdag, M.; Poli, G.; Angeli, A.; Lucarini, E.; Tuccinardi, T.; Di Cesare Mannelli, L.; Selleri, S.; Ghelardini, C.; Winum, J. -Y.; Carta, F.; Supuran, C. T. | |
| Virtual screening identifies a PIN1 inhibitor with possible antiovarian cancer effects | 1-gen-2019 | Russo Spena, C.; De Stefano, L.; Poli, G.; Granchi, C.; El Boustani, M.; Ecca, F.; Grassi, G.; Grassi, M.; Canzonieri, V.; Giordano, A.; Tuccinardi, T.; Caligiuri, I.; Rizzolio, F. | |
| Rutin as promising drug for the treatment of Parkinson’s disease: an assessment of MAO-B inhibitory potential by docking, molecular dynamics and DFT studies | 1-gen-2019 | Azam, F.; Abodabos, H. S.; Taban, I. M.; Rfieda, A. R.; Mahmood, D.; Anwar, M. J.; Khan, S.; Sizochenko, N.; Poli, G.; Tuccinardi, T.; Ali, H. I. | |
| Computationally driven discovery of phenyl(piperazin-1-yl)methanone derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors | 1-gen-2019 | Poli, Giulio; Lapillo, Margherita; Jha, Vibhu; Mouawad, Nayla; Caligiuri, Isabella; Macchia, Marco; Minutolo, Filippo; Rizzolio, Flavio; Tuccinardi, Tiziano; Granchi, Carlotta | |
| Optimization of a Benzoylpiperidine Class Identifies a Highly Potent and Selective Reversible Monoacylglycerol Lipase (MAGL) Inhibitor | 1-gen-2019 | Granchi, Carlotta; Lapillo, Margherita; Glasmacher, Sandra; Bononi, Giulia; Licari, Cristina; Poli, Giulio; El Boustani, Maguie; Caligiuri, Isabella; Rizzolio, Flavio; Gertsch, Jürg; Macchia, Marco; Minutolo, Filippo; Tuccinardi, Tiziano; Chicca, Andrea | |
| L-DOPA-quinone Mediated Recovery from GIRK Channel Firing Inhibition in Dopaminergic Neurons | 1-gen-2019 | Bizzarri, B. M.; Botta, L.; Aversa, D.; Mercuri, N. B.; Poli, G.; Barbieri, A.; Berretta, N.; Saladino, R. |
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