| Nome |
# |
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TSPO ligand residence time: a new parameter to predict compound neurosteroidogenic efficacy, file e0d6c926-d013-fcf8-e053-d805fe0aa794
|
210
|
|
TSPO PIGA ligands promote neurosteroidogenesis and human astrocyte well-being, file e0d6c927-910c-fcf8-e053-d805fe0aa794
|
204
|
|
TSPO ligand residence time influences human glioblastoma multiforme cell death/life balance, file e0d6c926-900d-fcf8-e053-d805fe0aa794
|
194
|
|
Novel fluorescent triazinobenzimidazole derivatives as probes for labelling human A1 and A2B adenosine receptor subtypes, file e0d6c92b-c55e-fcf8-e053-d805fe0aa794
|
155
|
|
Long lasting MDM2/Translocator protein modulator: a new strategy for irreversible apoptosis of human glioblastoma cells, file e0d6c927-c866-fcf8-e053-d805fe0aa794
|
150
|
|
Long lasting inhibition of Mdm2-p53 interaction potentiates mesenchymal stem cell differentiation into osteoblasts, file e0d6c92c-354e-fcf8-e053-d805fe0aa794
|
94
|
|
Iminothioethers as Hydrogen Sulfide Donors: From the Gasotransmitter Release to the Vascular Effects, file e0d6c92b-82e4-fcf8-e053-d805fe0aa794
|
59
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|
Deepening the Topology of the Translocator Protein Binding Site by Novel N,N-Dialkyl-2-arylindol-3-ylglyoxylamides, file e0d6c92b-cb7f-fcf8-e053-d805fe0aa794
|
48
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|
Apoptosis Therapy in Cancer: The First Single-molecule Co-activating p53 and the Translocator Protein in Glioblastoma, file e0d6c929-3740-fcf8-e053-d805fe0aa794
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47
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|
Sulfonamides incorporating heteropolycyclic scaffolds show potent inhibitory action against carbonic anhydrase isoforms I, II, IX and XII, file e0d6c92b-b770-fcf8-e053-d805fe0aa794
|
37
|
|
4-Substituted Benzenesulfonamides Incorporating Bi/Tricyclic Moieties Act as Potent and Isoform-Selective Carbonic Anhydrase II/IX Inhibitors, file e0d6c92b-b587-fcf8-e053-d805fe0aa794
|
31
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|
New insights in the structure-activity relationships of 2-phenylamino-substituted benzothiopyrano[4,3-d]pyrimidines as kinase inhibitors, file e0d6c92b-9166-fcf8-e053-d805fe0aa794
|
29
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Exploiting the 4-Phenylquinazoline Scaffold for the Development of High Affinity Fluorescent Probes for the Translocator Protein (TSPO), file e0d6c930-7bf9-fcf8-e053-d805fe0aa794
|
27
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|
Lead Optimization of 2-Phenylindolylglyoxylyldipeptide Murine Double Minute (MDM)2/Translocator Protein (TSPO) Dual Inhibitors for the Treatment of Gliomas, file e0d6c930-9943-fcf8-e053-d805fe0aa794
|
25
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|
Phenylpyrazolo[1,5-a]quinazolin-5(4H)-one: a suitable scaffold for the development of non-camptothecin Topoisomerase I (Top1) inhibitors, file e0d6c92c-5c4f-fcf8-e053-d805fe0aa794
|
20
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The Alpha Keto Amide Moiety as a Privileged Motif in Medicinal Chemistry: Current Insights and Emerging Opportunities, file e0d6c931-a390-fcf8-e053-d805fe0aa794
|
16
|
|
Residence Time (RT), a new parameter to predict neurosteroidogenic efficacy of Translocator Protein (TSPO) ligands: N,N-dialkyl-2-arylindol-3-ylglyoxylamides, a case study, file e0d6c92b-a2b1-fcf8-e053-d805fe0aa794
|
14
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Multiple Topoisomerase I (TopoI), Topoisomerase II (TopoII) and Tyrosyl-DNA Phosphodiesterase (TDP) inhibitors in the development of anticancer drugs, file e0d6c92f-81fc-fcf8-e053-d805fe0aa794
|
12
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|
Targeting the 18-kDa translocator protein: Recent perspectives for neuroprotection, file e0d6c931-26fb-fcf8-e053-d805fe0aa794
|
8
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|
Exploiting the 4-Phenylquinazoline Scaffold for the Development of High Affinity Fluorescent Probes for the Translocator Protein (TSPO), file e0d6c92a-0b3b-fcf8-e053-d805fe0aa794
|
7
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|
Benzothiopyranoindole- and pyridothiopyranoindole-based antiproliferative agents targeting topoisomerases, file e0d6c92e-466c-fcf8-e053-d805fe0aa794
|
5
|
|
A mixed-valence diruthenium(ii,iii) complex endowed with high stability: from experimental evidence to theoretical interpretation, file e0d6c92f-13e4-fcf8-e053-d805fe0aa794
|
5
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|
An update into the medicinal chemistry of translocator protein (TSPO) ligands, file e0d6c92f-2892-fcf8-e053-d805fe0aa794
|
5
|
|
Unbinding of Translocator Protein 18 kDa (TSPO) Ligands: From in Vitro Residence Time to in Vivo Efficacy via in Silico Simulations, file e0d6c92e-1981-fcf8-e053-d805fe0aa794
|
4
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|
Strategies for the improvement of metal-based chemotherapeutic treatments, file e0d6c931-2203-fcf8-e053-d805fe0aa794
|
4
|
|
Phenylpyrazolo[1,5-a]quinazolin-5(4H)-one: a suitable scaffold for the development of non-camptothecin Topoisomerase I (Top1) inhibitors, file e0d6c926-3fe9-fcf8-e053-d805fe0aa794
|
3
|
|
Deepening the Topology of the Translocator Protein Binding Site by Novel N,N-Dialkyl-2-arylindol-3-ylglyoxylamides, file e0d6c927-1b29-fcf8-e053-d805fe0aa794
|
3
|
|
Iminothioethers as Hydrogen Sulfide Donors: From the Gasotransmitter Release to the Vascular Effects, file e0d6c929-afb4-fcf8-e053-d805fe0aa794
|
3
|
|
Residence Time (RT), a new parameter to predict neurosteroidogenic efficacy of Translocator Protein (TSPO) ligands: N,N-dialkyl-2-arylindol-3-ylglyoxylamides, a case study, file e0d6c92b-a2ae-fcf8-e053-d805fe0aa794
|
3
|
|
Sulfonamides incorporating heteropolycyclic scaffolds show potent inhibitory action against carbonic anhydrase isoforms I, II, IX and XII, file e0d6c92b-b585-fcf8-e053-d805fe0aa794
|
3
|
|
Novel 2-substituted-benzimidazole-6-sulfonamides as carbonic anhydrase inhibitors: synthesis, biological evaluation against isoforms I, II, IX and XII and molecular docking studies, file e0d6c92e-8301-fcf8-e053-d805fe0aa794
|
3
|
|
Carbonic anhydrase activation profile of indole-based derivatives, file e0d6c931-882d-fcf8-e053-d805fe0aa794
|
3
|
|
De novo neurosteroidogenesis in human microglia: Involvement of the 18 kda translocator protein, file e0d6c931-a2a0-fcf8-e053-d805fe0aa794
|
3
|
|
Carbonic Anhydrase Activators for Neurodegeneration: An Overview, file e0d6c932-4879-fcf8-e053-d805fe0aa794
|
3
|
|
Modulation of A2B Adenosine Receptor by 1-Benzyl-3-ketoindole Derivatives, file e0d6c926-3fe8-fcf8-e053-d805fe0aa794
|
2
|
|
4-Substituted Benzenesulfonamides Incorporating Bi/Tricyclic Moieties Act as Potent and Isoform-Selective Carbonic Anhydrase II/IX Inhibitors, file e0d6c92a-e588-fcf8-e053-d805fe0aa794
|
2
|
|
Discovery of Pyrido[3′,2′:5,6]thiopyrano[4,3- d]pyrimidine-Based Antiproliferative Multikinase Inhibitors, file e0d6c92d-026d-fcf8-e053-d805fe0aa794
|
2
|
|
Multiple Topoisomerase I (TopoI), Topoisomerase II (TopoII) and Tyrosyl-DNA Phosphodiesterase (TDP) inhibitors in the development of anticancer drugs, file e0d6c92f-81fb-fcf8-e053-d805fe0aa794
|
2
|
|
Novel positive allosteric modulators of A2B adenosine receptor acting as bone mineralisation promoters, file e0d6c930-154d-fcf8-e053-d805fe0aa794
|
2
|
|
Lead Optimization of 2-Phenylindolylglyoxylyldipeptide Murine Double Minute (MDM)2/Translocator Protein (TSPO) Dual Inhibitors for the Treatment of Gliomas, file e0d6c930-69b9-fcf8-e053-d805fe0aa794
|
2
|
|
null, file e0d6c930-eab8-fcf8-e053-d805fe0aa794
|
2
|
|
Tetrahydroquinazole-based secondary sulphonamides as carbonic anhydrase inhibitors: synthesis, biological evaluation against isoforms I, II, IV, and IX, and computational studies, file e0d6c931-7dee-fcf8-e053-d805fe0aa794
|
2
|
|
Allosterism vs. Orthosterism: Recent Findings and Future Perspectives on A2B AR Physio-Pathological Implications, file e0d6c931-8347-fcf8-e053-d805fe0aa794
|
2
|
|
New antiproliferative agents derived from tricyclic 3,4-dihydrobenzo[4,5]imidazo[1,2-a][1,3,5]triazine scaffold: synthesis and pharmacological effects, file 8e91915f-52da-40bb-baa1-f895bec21f13
|
1
|
|
Structure-Activity Relationship Refinement and Further Assessment of 4-Phenylquinazoline-2-carboxamide Translocator Protein Ligands as Antiproliferative Agents in Human Glioblastoma Tumors., file e0d6c929-31e8-fcf8-e053-d805fe0aa794
|
1
|
|
New insights in the structure-activity relationships of 2-phenylamino-substituted benzothiopyrano[4,3-d]pyrimidines as kinase inhibitors, file e0d6c92b-e71c-fcf8-e053-d805fe0aa794
|
1
|
|
Unbinding of Translocator Protein 18 kDa (TSPO) Ligands: From in Vitro Residence Time to in Vivo Efficacy via in Silico Simulations, file e0d6c92d-ecd7-fcf8-e053-d805fe0aa794
|
1
|
|
A mixed-valence diruthenium(ii,iii) complex endowed with high stability: from experimental evidence to theoretical interpretation, file e0d6c92f-2b3e-fcf8-e053-d805fe0aa794
|
1
|
|
Inhibition studies on carbonic anhydrase isoforms I, II, IV and IX with N-arylsubstituted secondary sulfonamides featuring a bicyclic tetrahydroindazole scaffold, file e0d6c931-21c9-fcf8-e053-d805fe0aa794
|
1
|
|
Two mixed valence diruthenium(ii,iii) isomeric complexes show different anticancer properties, file e0d6c931-76d6-fcf8-e053-d805fe0aa794
|
1
|
|
Tetrahydroquinazole-based secondary sulphonamides as carbonic anhydrase inhibitors: synthesis, biological evaluation against isoforms I, II, IV, and IX, and computational studies, file e0d6c931-a0eb-fcf8-e053-d805fe0aa794
|
1
|
|
Two mixed valence diruthenium(ii,iii) isomeric complexes show different anticancer properties, file e0d6c931-a464-fcf8-e053-d805fe0aa794
|
1
|
| Totale |
1464 |