MINUTOLO, FILIPPO Statistiche
MINUTOLO, FILIPPO
DIPARTIMENTO DI FARMACIA
Design, synthesis, ADME and biological evaluation of benzylpiperidine and benzylpiperazine derivatives as novel reversible monoacylglycerol lipase (MAGL) inhibitors
2024-01-01 Di Stefano, Miriana; Masoni, Samuele; Bononi, Giulia; Poli, Giulio; Galati, Salvatore; Gado, Francesca; Manzi, Simone; Vagaggini, Chiara; Brai, Annalaura; Caligiuri, Isabella; Asif, Kanwal; Rizzolio, Flavio; Macchia, Marco; Chicca, Andrea; Sodi, Andrea; Di Bussolo, Valeria; Minutolo, Filippo; Meier, Philip; Gertsch, Jürg; Granchi, Carlotta; Dreassi, Elena; Tuccinardi, Tiziano
Nuovi agenti antivirali a struttura N-idrossiindrol-carbossamidica
2024-01-01 Minutolo, Filippo; Pistello, Mauro; DI BUSSOLO, Valeria; Freer, Giulia; Quaranta, Paola; Granchi, Carlotta; Tuccinardi, Tiziano; Poli, Giulio; Bononi, Giulia; Masoni, Samuele
The Benzoylpiperidine Fragment as a Privileged Structure in Medicinal Chemistry: A Comprehensive Review
2024-01-01 Bononi, Giulia; Lonzi, Chiara; Tuccinardi, Tiziano; Minutolo, Filippo; Granchi, Carlotta
Combined inhibition of pyruvate dehydrogenase kinase 1 and lactate dehydrogenase a induces metabolic and signaling reprogramming and enhances lung adenocarcinoma cell killing
2023-01-01 Zhou, Yan; Guo, Yizhen; Ran, Maoxin; Shan, Wenying; Granchi, Carlotta; Giovannetti, Elisa; Minutolo, Filippo; Peters, Godefridus J.; Tam, Kin Yip
First-in-Class Dual Targeting Compounds for the Management of Seizures in Glucose Transporter Type 1 Deficiency Syndrome
2023-01-01 Angeli, Andrea; Ferraroni, Marta; Granchi, Carlotta; Minutolo, Filippo; Chen, Xiaozhuo; Shriwas, Pratik; Russo, Emilio; Leo, Antonio; Selleri, Silvia; Carta, Fabrizio; Supuran, Claudiu T
Metabolic Effects of New Glucose Transporter (GLUT-1) and Lactate Dehydrogenase-A (LDH-A) Inhibitors against Chemoresistant Malignant Mesothelioma
2023-01-01 Franczak, Marika A.; Krol, Oliwia; Harasim, Gabriela; Jedrzejewska, Agata; Zaffaroni, Nadia; Granchi, Carlotta; Minutolo, Filippo; Avan, Amir; Giovannetti, Elisa; Smolenski, Ryszard T.; Peters, Godefridus J.
Sirtuin 1-activating derivatives belonging to the anilinopyridine class displaying in vivo cardioprotective activities
2023-01-01 Bononi, G.; Citi, V.; Martelli, A.; Poli, G.; Tuccinardi, T.; Granchi, C.; Testai, L.; Calderone, V.; Minutolo, F.
Functionalized aliphatic polyketones with germicide activity
2022-01-01 Araya-Hermosilla, E.; Parlanti, P.; Gemmi, M.; Mattoli, V.; Di Pietro, S.; Iacopini, D.; Granchi, C.; Turchi, B.; Fratini, F.; Di Bussolo, V.; Minutolo, F.; Picchioni, F.; Pucci, A.
Historical perspective of tumor glycolysis: a century with Otto Warburg
2022-01-01 Bononi, Giulia; Masoni, Samuele; Di Bussolo, Valeria; Tuccinardi, Tiziano; Granchi, Carlotta; Minutolo, Filippo
MAGL inhibitor NanoMicellar formulation (MAGL-NanoMicellar) for the development of an antiglaucoma eye drop
2022-01-01 Chetoni, Patrizia; Burgalassi, Susi; Zucchetti, Erica; Granchi, Carlotta; Minutolo, Filippo; Tampucci, Silvia; Monti, Daniela
New PIN1 inhibitors identified through a pharmacophore-driven, hierarchical consensus docking strategy
2022-01-01 Poli, Giulio; Di Stefano, Miriana; Estevez, Joan Arias; Minutolo, Filippo; Granchi, Carlotta; Giordano, Antonio; Parisi, Salvatore; Mauceri, Matteo; Canzonieri, Vincenzo; Macchia, Marco; Caligiuri, Isabella; Tuccinardi, Tiziano; Rizzolio, Flavio
New Synthetic Analogues of Natural Polyphenols as Sirtuin 1-Activating Compounds
2022-01-01 Bononi, G.; Flori, L.; Citi, V.; Acciai, C.; Nocilla, V.; Martelli, A.; Poli, G.; Tuccinardi, T.; Granchi, C.; Testai, L.; Calderone, V.; Minutolo, F.
Reversible Monoacylglycerol Lipase Inhibitors: Discovery of a New Class of Benzylpiperidine Derivatives
2022-01-01 Bononi, Giulia; Di Stefano, Miriana; Poli, Giulio; Ortore, Gabriella; Meier, Philip; Masetto, Francesca; Caligiuri, Isabella; Rizzolio, Flavio; Macchia, Marco; Chicca, Andrea; Avan, Amir; Giovannetti, Elisa; Vagaggini, Chiara; Brai, Annalaura; Dreassi, Elena; Valoti, Massimo; Minutolo, Filippo; Granchi, Carlotta; Gertsch, Jürg; Tuccinardi, Tiziano
Sirtuin 1-Activating Compounds: Discovery of a Class of Thiazole-Based Derivatives
2022-01-01 Bononi, G.; Citi, V.; Lapillo, M.; Martelli, A.; Poli, G.; Tuccinardi, T.; Granchi, C.; Testai, L.; Calderone, V.; Minutolo, F.
The effect of lactate dehydrogenase-A inhibition on intracellular nucleotides and mitochondrial respiration in pancreatic cancer cells
2022-01-01 Franczak, Marika; Kutryb-Zajac, Barbara; El Hassouni, Btissame; Giovannetti, Elisa; Granchi, Carlotta; Minutolo, Filippo; Smolenski, Ryszard T; Peters, Godefridus J
An updated patent review of monoacylglycerol lipase (MAGL) inhibitors (2018-present)
2021-01-01 Bononi, G.; Poli, G.; Rizzolio, F.; Tuccinardi, T.; Macchia, M.; Minutolo, F.; Granchi, C.
Design, synthesis and biological evaluation of second-generation benzoylpiperidine derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors
2021-01-01 Granchi, C.; Bononi, G.; Ferrisi, R.; Gori, E.; Mantini, G.; Glasmacher, S.; Poli, G.; Palazzolo, S.; Caligiuri, I.; Rizzolio, F.; Canzonieri, V.; Perin, T.; Gertsch, J.; Sodi, A.; Giovannetti, E.; Macchia, M.; Minutolo, F.; Tuccinardi, T.; Chicca, A.
Diagnostic probes to detect cells and tissues afflicted with a pathological or metabolic condition by means of infrared spectroscopy
2021-01-01 Minutolo, Filippo; DI BUSSOLO, Valeria; Granchi, Carlotta; Funel, Niccola; Giovannetti, Elisa; Sartini, Stefania; Bononi, Giulia; DI PIETRO, Sebastiano; Fortunato, Serena; Paltrinieri, Erica; Cicio, Gaspare; Iaccarino, Rita
Discovery of a new ATP-citrate lyase (ACLY) inhibitor identified by a pharmacophore-based virtual screening study
2021-01-01 Jha, V.; Galati, S.; Volpi, V.; Ciccone, L.; Minutolo, F.; Rizzolio, F.; Granchi, C.; Poli, G.; Tuccinardi, T.
Discovery of monoacylglycerol lipase (MAGL) inhibitors based on a pharmacophore-guided virtual screening study
2021-01-01 Jha, V.; Biagi, M.; Spinelli, V.; Di Stefano, M. D.; Macchia, M.; Minutolo, F.; Granchi, C.; Poli, G.; Tuccinardi, T.
Titolo | Data di pubblicazione | Autore(i) | File |
---|---|---|---|
Design, synthesis, ADME and biological evaluation of benzylpiperidine and benzylpiperazine derivatives as novel reversible monoacylglycerol lipase (MAGL) inhibitors | 1-gen-2024 | Di Stefano, Miriana; Masoni, Samuele; Bononi, Giulia; Poli, Giulio; Galati, Salvatore; Gado, Francesca; Manzi, Simone; Vagaggini, Chiara; Brai, Annalaura; Caligiuri, Isabella; Asif, Kanwal; Rizzolio, Flavio; Macchia, Marco; Chicca, Andrea; Sodi, Andrea; Di Bussolo, Valeria; Minutolo, Filippo; Meier, Philip; Gertsch, Jürg; Granchi, Carlotta; Dreassi, Elena; Tuccinardi, Tiziano | |
Nuovi agenti antivirali a struttura N-idrossiindrol-carbossamidica | 1-gen-2024 | Minutolo, Filippo; Pistello, Mauro; DI BUSSOLO, Valeria; Freer, Giulia; Quaranta, Paola; Granchi, Carlotta; Tuccinardi, Tiziano; Poli, Giulio; Bononi, Giulia; Masoni, Samuele | |
The Benzoylpiperidine Fragment as a Privileged Structure in Medicinal Chemistry: A Comprehensive Review | 1-gen-2024 | Bononi, Giulia; Lonzi, Chiara; Tuccinardi, Tiziano; Minutolo, Filippo; Granchi, Carlotta | |
Combined inhibition of pyruvate dehydrogenase kinase 1 and lactate dehydrogenase a induces metabolic and signaling reprogramming and enhances lung adenocarcinoma cell killing | 1-gen-2023 | Zhou, Yan; Guo, Yizhen; Ran, Maoxin; Shan, Wenying; Granchi, Carlotta; Giovannetti, Elisa; Minutolo, Filippo; Peters, Godefridus J.; Tam, Kin Yip | |
First-in-Class Dual Targeting Compounds for the Management of Seizures in Glucose Transporter Type 1 Deficiency Syndrome | 1-gen-2023 | Angeli, Andrea; Ferraroni, Marta; Granchi, Carlotta; Minutolo, Filippo; Chen, Xiaozhuo; Shriwas, Pratik; Russo, Emilio; Leo, Antonio; Selleri, Silvia; Carta, Fabrizio; Supuran, Claudiu T | |
Metabolic Effects of New Glucose Transporter (GLUT-1) and Lactate Dehydrogenase-A (LDH-A) Inhibitors against Chemoresistant Malignant Mesothelioma | 1-gen-2023 | Franczak, Marika A.; Krol, Oliwia; Harasim, Gabriela; Jedrzejewska, Agata; Zaffaroni, Nadia; Granchi, Carlotta; Minutolo, Filippo; Avan, Amir; Giovannetti, Elisa; Smolenski, Ryszard T.; Peters, Godefridus J. | |
Sirtuin 1-activating derivatives belonging to the anilinopyridine class displaying in vivo cardioprotective activities | 1-gen-2023 | Bononi, G.; Citi, V.; Martelli, A.; Poli, G.; Tuccinardi, T.; Granchi, C.; Testai, L.; Calderone, V.; Minutolo, F. | |
Functionalized aliphatic polyketones with germicide activity | 1-gen-2022 | Araya-Hermosilla, E.; Parlanti, P.; Gemmi, M.; Mattoli, V.; Di Pietro, S.; Iacopini, D.; Granchi, C.; Turchi, B.; Fratini, F.; Di Bussolo, V.; Minutolo, F.; Picchioni, F.; Pucci, A. | |
Historical perspective of tumor glycolysis: a century with Otto Warburg | 1-gen-2022 | Bononi, Giulia; Masoni, Samuele; Di Bussolo, Valeria; Tuccinardi, Tiziano; Granchi, Carlotta; Minutolo, Filippo | |
MAGL inhibitor NanoMicellar formulation (MAGL-NanoMicellar) for the development of an antiglaucoma eye drop | 1-gen-2022 | Chetoni, Patrizia; Burgalassi, Susi; Zucchetti, Erica; Granchi, Carlotta; Minutolo, Filippo; Tampucci, Silvia; Monti, Daniela | |
New PIN1 inhibitors identified through a pharmacophore-driven, hierarchical consensus docking strategy | 1-gen-2022 | Poli, Giulio; Di Stefano, Miriana; Estevez, Joan Arias; Minutolo, Filippo; Granchi, Carlotta; Giordano, Antonio; Parisi, Salvatore; Mauceri, Matteo; Canzonieri, Vincenzo; Macchia, Marco; Caligiuri, Isabella; Tuccinardi, Tiziano; Rizzolio, Flavio | |
New Synthetic Analogues of Natural Polyphenols as Sirtuin 1-Activating Compounds | 1-gen-2022 | Bononi, G.; Flori, L.; Citi, V.; Acciai, C.; Nocilla, V.; Martelli, A.; Poli, G.; Tuccinardi, T.; Granchi, C.; Testai, L.; Calderone, V.; Minutolo, F. | |
Reversible Monoacylglycerol Lipase Inhibitors: Discovery of a New Class of Benzylpiperidine Derivatives | 1-gen-2022 | Bononi, Giulia; Di Stefano, Miriana; Poli, Giulio; Ortore, Gabriella; Meier, Philip; Masetto, Francesca; Caligiuri, Isabella; Rizzolio, Flavio; Macchia, Marco; Chicca, Andrea; Avan, Amir; Giovannetti, Elisa; Vagaggini, Chiara; Brai, Annalaura; Dreassi, Elena; Valoti, Massimo; Minutolo, Filippo; Granchi, Carlotta; Gertsch, Jürg; Tuccinardi, Tiziano | |
Sirtuin 1-Activating Compounds: Discovery of a Class of Thiazole-Based Derivatives | 1-gen-2022 | Bononi, G.; Citi, V.; Lapillo, M.; Martelli, A.; Poli, G.; Tuccinardi, T.; Granchi, C.; Testai, L.; Calderone, V.; Minutolo, F. | |
The effect of lactate dehydrogenase-A inhibition on intracellular nucleotides and mitochondrial respiration in pancreatic cancer cells | 1-gen-2022 | Franczak, Marika; Kutryb-Zajac, Barbara; El Hassouni, Btissame; Giovannetti, Elisa; Granchi, Carlotta; Minutolo, Filippo; Smolenski, Ryszard T; Peters, Godefridus J | |
An updated patent review of monoacylglycerol lipase (MAGL) inhibitors (2018-present) | 1-gen-2021 | Bononi, G.; Poli, G.; Rizzolio, F.; Tuccinardi, T.; Macchia, M.; Minutolo, F.; Granchi, C. | |
Design, synthesis and biological evaluation of second-generation benzoylpiperidine derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors | 1-gen-2021 | Granchi, C.; Bononi, G.; Ferrisi, R.; Gori, E.; Mantini, G.; Glasmacher, S.; Poli, G.; Palazzolo, S.; Caligiuri, I.; Rizzolio, F.; Canzonieri, V.; Perin, T.; Gertsch, J.; Sodi, A.; Giovannetti, E.; Macchia, M.; Minutolo, F.; Tuccinardi, T.; Chicca, A. | |
Diagnostic probes to detect cells and tissues afflicted with a pathological or metabolic condition by means of infrared spectroscopy | 1-gen-2021 | Minutolo, Filippo; DI BUSSOLO, Valeria; Granchi, Carlotta; Funel, Niccola; Giovannetti, Elisa; Sartini, Stefania; Bononi, Giulia; DI PIETRO, Sebastiano; Fortunato, Serena; Paltrinieri, Erica; Cicio, Gaspare; Iaccarino, Rita | |
Discovery of a new ATP-citrate lyase (ACLY) inhibitor identified by a pharmacophore-based virtual screening study | 1-gen-2021 | Jha, V.; Galati, S.; Volpi, V.; Ciccone, L.; Minutolo, F.; Rizzolio, F.; Granchi, C.; Poli, G.; Tuccinardi, T. | |
Discovery of monoacylglycerol lipase (MAGL) inhibitors based on a pharmacophore-guided virtual screening study | 1-gen-2021 | Jha, V.; Biagi, M.; Spinelli, V.; Di Stefano, M. D.; Macchia, M.; Minutolo, F.; Granchi, C.; Poli, G.; Tuccinardi, T. |