DNA methylation plays a critical role in breast cancer development. Previous studies have identified DNA methylation marks in white blood cells as promising biomarkers for breast cancer. However, these studies were limited by low statistical power and potential biases. Utilizing a new methodology, we investigated DNA methylation marks for their associations with breast cancer risk.

Genetically predicted levels of DNA methylation biomarkers and breast cancer risk: data from 228,951 women of European descent

Campa, Daniele;
2019-01-01

Abstract

DNA methylation plays a critical role in breast cancer development. Previous studies have identified DNA methylation marks in white blood cells as promising biomarkers for breast cancer. However, these studies were limited by low statistical power and potential biases. Utilizing a new methodology, we investigated DNA methylation marks for their associations with breast cancer risk.
2019
Yang, Yaohua; Wu, Lang; Shu, Xiao-Ou; Cai, Qiuyin; Shu, Xiang; Li, Bingshan; Guo, Xingyi; Ye, Fei; Michailidou, Kyriaki; Bolla, Manjeet K; Wang, Qin; Dennis, Joe; Andrulis, Irene L; Brenner, Hermann; Chenevix-Trench, Georgia; Campa, Daniele; Castelao, Jose E; Gago-Dominguez, Manuela; Dörk, Thilo; Hollestelle, Antoinette; Lophatananon, Artitaya; Muir, Kenneth; Neuhausen, Susan L; Olsson, Håkan; Sandler, Dale P; Simard, Jacques; Kraft, Peter; Pharoah, Paul D P; Easton, Douglas F; Zheng, Wei; Long, Jirong
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/1027509
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