Non-Alcoholic Fatty Liver Disease (NAFLD) has been associated with reduced endogenous insulin clearance (EIC) and hepatic insulin resistance (HIRI). These relationships, however, might be differentially affected by the ethnic background, as populations of African ancestry are typically featured with reduced intrahepatic fat content (HFF%) but impaired EIC. Therefore, we evaluated the influence of the ethnicity on the relationships between HFF%, EIC and HIRI.
Intrahepatic fat, irrespective of ethnicity, is associated with reduced endogenous insulin clearance and hepatic insulin resistance in obese youths: a cross-sectional and longitudinal study from the Yale Pediatric NAFLD cohort
Tricò, Domenico
Primo
;
2020-01-01
Abstract
Non-Alcoholic Fatty Liver Disease (NAFLD) has been associated with reduced endogenous insulin clearance (EIC) and hepatic insulin resistance (HIRI). These relationships, however, might be differentially affected by the ethnic background, as populations of African ancestry are typically featured with reduced intrahepatic fat content (HFF%) but impaired EIC. Therefore, we evaluated the influence of the ethnicity on the relationships between HFF%, EIC and HIRI.File in questo prodotto:
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