Objective: Authors review a series of 29 extra-skeletal Ewing Sarcoma (EES) Methods: They analyzed characteristics, prognostic factors and outcome of EES. Results: Authors report 60% Overall Survival (OS) and 56% of Event Free Survival (EFS) at 5 years. Better 5 years EFS was found in patients with localized disease (68.8%) compared to metastatic EES (33.3%) (p = 0.042). Radiotherapy + surgery offered the best local treatment (p=0.017). Volume (p = 0.032), Surgical margins (p = 0.01), metastatic disease (p = 0.0013) were a significant prognostic factor for OS at 5-yrs. Conclusion: Adequate margins and surgery+radiotherapy improve Overall Survival.
Clinical features, prognostic factors and outcome in a series of 29 extra-skeletal Ewing Sarcoma. Adequate margins and surgery-radiotherapy association improve overall survival
Capanna R.;
2020-01-01
Abstract
Objective: Authors review a series of 29 extra-skeletal Ewing Sarcoma (EES) Methods: They analyzed characteristics, prognostic factors and outcome of EES. Results: Authors report 60% Overall Survival (OS) and 56% of Event Free Survival (EFS) at 5 years. Better 5 years EFS was found in patients with localized disease (68.8%) compared to metastatic EES (33.3%) (p = 0.042). Radiotherapy + surgery offered the best local treatment (p=0.017). Volume (p = 0.032), Surgical margins (p = 0.01), metastatic disease (p = 0.0013) were a significant prognostic factor for OS at 5-yrs. Conclusion: Adequate margins and surgery+radiotherapy improve Overall Survival.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.


