In humans, risk of thrombotic events is a major concern in people affected by ulcerative cholitis and Chron's disease. Platelets number (PLTs), increased PLTs activation, mean platelet volume (MPV) reduction and immune-mediated thrombocytopenia are reported in patients with chronic enteropathies. In dogs with inflammatory bowel disease, thrombocytopenia or thrombocytosis are reported to be 2.5-13% or 31% respectively. Platelet-to-lymphocyte ratio (PLR) has been suggested as marker of active disease in humans with Chron's disease.This study investigated PLTs, MPV and PLR in dogs with immunosuppressant-responsive enteropathy (IRE).
Platelet abnormalities and platelet-to-lymphocyte ratio (PLR) in canine immunosuppressant-responsive enteropathy (ire): a retrospective study on 41 patients
Gori E.;Lubas G.;Marchetti V.
2019-01-01
Abstract
In humans, risk of thrombotic events is a major concern in people affected by ulcerative cholitis and Chron's disease. Platelets number (PLTs), increased PLTs activation, mean platelet volume (MPV) reduction and immune-mediated thrombocytopenia are reported in patients with chronic enteropathies. In dogs with inflammatory bowel disease, thrombocytopenia or thrombocytosis are reported to be 2.5-13% or 31% respectively. Platelet-to-lymphocyte ratio (PLR) has been suggested as marker of active disease in humans with Chron's disease.This study investigated PLTs, MPV and PLR in dogs with immunosuppressant-responsive enteropathy (IRE).| File | Dimensione | Formato | |
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470 - Pierini et al PLT alterations and PLR in 41 dogs with IRE Proc Sisvet_2019.pdf
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