Ten critically-ill patients with either bacteremia or ventilator-associated pneumonia caused by carbapenem-resistant A. baumannii, S. maltophilia or NDM-producing K. pneumoniae received cefiderocol. All strains had MIC ≤2 μg/mL. Thirty-day clinical success and survival rates were 70% and 90%, respectively. Two patients had a microbiological failure. Future prospective studies are warranted.
Cefiderocol as rescue therapy for Acinetobacter baumannii and other carbapenem-resistant Gram-Negative infections in ICU patients
Falcone, Marco;Tiseo, Giusy;Vecchione, Alessandra;Casella, Costanza;Forfori, Francesco;Guarracino, Fabio;Barnini, Simona;Menichetti, Francesco
2020-01-01
Abstract
Ten critically-ill patients with either bacteremia or ventilator-associated pneumonia caused by carbapenem-resistant A. baumannii, S. maltophilia or NDM-producing K. pneumoniae received cefiderocol. All strains had MIC ≤2 μg/mL. Thirty-day clinical success and survival rates were 70% and 90%, respectively. Two patients had a microbiological failure. Future prospective studies are warranted.File in questo prodotto:
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