Objective: To describe the possibility that dopamine infusion can prevent early diagnosis of congenital hypothyroidism. Design: Case report. Setting: Medical neonatal intensive care unit of a tertiary academic medical center. Patients: We report four preterm newborns affected by transient primary congenital hypothyroidism who showed low serum thyroxine and normal thyroid-stimulating hormone concentrations on primary screening performed during treatment with dopamine. Interventions: Thyroid reevaluation screening after dopamine discontinuation. Measurements and Main Results: Thyroid reevaluation showed elevated thyroid-stimulating hormone levels. Conclusion: We emphasize that dopamine capacity to suppress thyroid-stimulating hormone could prevent early diagnosis of congenital hypothyroidism. We suggest all newborns to be tested simultaneously for thyroid-stimulating hormone and thyroxine values at primary screening. A reevaluation of thyroid hormones after dopamine discontinuation is advisable in patients treated with dopamine. Copyright © 2006 by the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.

Dopamine infusion: A possible cause of undiagnosed congenital hypothyroidism in preterm infants

Filippi L.;
2006-01-01

Abstract

Objective: To describe the possibility that dopamine infusion can prevent early diagnosis of congenital hypothyroidism. Design: Case report. Setting: Medical neonatal intensive care unit of a tertiary academic medical center. Patients: We report four preterm newborns affected by transient primary congenital hypothyroidism who showed low serum thyroxine and normal thyroid-stimulating hormone concentrations on primary screening performed during treatment with dopamine. Interventions: Thyroid reevaluation screening after dopamine discontinuation. Measurements and Main Results: Thyroid reevaluation showed elevated thyroid-stimulating hormone levels. Conclusion: We emphasize that dopamine capacity to suppress thyroid-stimulating hormone could prevent early diagnosis of congenital hypothyroidism. We suggest all newborns to be tested simultaneously for thyroid-stimulating hormone and thyroxine values at primary screening. A reevaluation of thyroid hormones after dopamine discontinuation is advisable in patients treated with dopamine. Copyright © 2006 by the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.
2006
Filippi, L.; Pezzati, M.; Cecchi, A.; Poggi, C.
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/1072210
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 23
  • ???jsp.display-item.citation.isi??? ND
social impact