Graves' orbitopathy (GO) is an autoimmune disease persisting when immunosuppression is achieved. Orbital fibroblasts from GO patients display peculiar phenotypes even if not exposed to autoimmunity, possibly reflecting genetic or epigenetic mechanisms, which we investigated here.
Genetic profiling of orbital fibroblasts from patients with Graves' orbitopathy
Dottore, Giovanna Rotondo;Bucci, Ilaria;Lanzolla, Giulia;Dallan, Iacopo;Sframeli, Angela;Torregrossa, Liborio;Casini, Giamberto;Basolo, Fulvio;Figus, Michele;Nardi, Marco;Marcocci, Claudio;Marinò, Michele
2021-01-01
Abstract
Graves' orbitopathy (GO) is an autoimmune disease persisting when immunosuppression is achieved. Orbital fibroblasts from GO patients display peculiar phenotypes even if not exposed to autoimmunity, possibly reflecting genetic or epigenetic mechanisms, which we investigated here.File in questo prodotto:
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