The synthesis of some amidic derivatives, obtained by condensation of various 5-substituted indoleglyoxylchlorides with physiologically important amines as tyramine, tryptamine and 5-aminouracil, is described. The preparation of one glycolyl derivative is also reported. Study of analgesic and antiinflammatory properties has shown only a feeble activity of these compounds.
|Autori:||A. Da Settimo; G. Primofiore; Marini A; C. Mori; J.S. franzone; R. Cirillo; C. Reboani.|
|Titolo:||Synthesis and antiinflammatory activity of some N-(5-substituted indole-3-ylglyoxylyl)amine derivatives.|
|Anno del prodotto:||1987|
|Appare nelle tipologie:||1.1 Articolo in rivista|