Introduction and aim of the study: to report the clinical outcome of trichiasis treatment by intradermal injections of 2,4 % hyaluronic acid in dogs and cats. Materials and methods: retrospective study on dogs and cats affected by eyelid trichiasis treated with intradermal injection of 2.4% hyaluronic acid. The procedure was used as an alternative to conventional surgery because of severe concomitant systemic diseases or refusal to general anesthesia by the owners. Mild sedation was needed only in aggressive or restless animals. Application of a topical anesthetic cream to the eyelid skin was performed on non-sedated animals. Hyaluronic acid was injected in a volume sufficient to obtain the disappearance of trichiasis (maximum volume 0.6 ml). Results: twenty-three animals (4 cats and 19 dogs) were treated, for a total of 34 eyes. No systemic adverse reactions were observed as consequences of the treatment. All subjects showed locally mild hyperemia, edema and ecchymosis. At the short-term follow-up (30 days post-treatment) 22/23 animals showed complete remission of trichiasis and associated symptoms. Recurrence of trichiasis was observed in 3/13 cases in which a follow-up of more than 6 months was available. Discussion: intradermal injection of hyaluronic acid represents a possible non-invasive therapeutic alternative to conventional surgical resolution of trichiasis, especially in animal patients with high anesthesiologic risk. However, the procedure cannot be considered a definitive treatment because trichiasis could recur at the reabsorption of filler, particularly in cats.

Introduzione e scopo del lavoro: riportare i risultati clinici ottenuti nel trattamento della trichiasi palpebrale con l’utilizzo di iniezioni intradermiche di acido ialuronico al 2,4%, nel cane e nel gatto. Materiali e metodi: studio retrospettivo su cani e gatti affetti da trichiasi palpebrale trattati con iniezione intradermica di acido ialuronico al 2,4% in alternativa alla chirurgia tradizionale, a causa di gravi malattie sistemiche concomitanti o mancata autorizzazione del proprietario all’anestesia generale. Solo negli animali aggressivi o molto agitati si è proceduto a lieve sedazione. Sui soggetti non sedati è stata applicata una crema anestetica sulla cute palpebrale. L’acido ialuronico è stato iniettato nel volume sufficiente a ottenere la scomparsa della trichiasi (volume massimo 0,6 ml). Risultati: Sono stati trattati 23 animali (4 gatti e 19 cani), per un totale di 34 occhi. Non sono state osservate reazioni avverse sistemiche in conseguenza al trattamento effettuato; a livello locale tutti i soggetti hanno manifestato lieve iperemia, edema ed ecchimosi. Al follow-up a breve termine (30 giorni post-trattamento) 22/23 animali hanno mostrato la completa remissione della trichiasi e dei sintomi clinici associati. Si è osservata recidiva della trichiasi in 3/13 casi nei quali era disponibile un follow-up superiore a 6 mesi. Discussione: L’iniezione intradermica di acido ialuronico rappresenta una possibile alternativa terapeutica non invasiva alla risoluzione chirurgica della trichiasi, specialmente nei pazienti con elevato rischio anestesiologico. Non può, però, essere considerato un trattamento definitivo in quanto con il riassorbimento del filler la trichiasi può recidivare, in particolare nel gatto.

Trattamento della trichiasi palpebrale nel cane e nel gatto con iniezione intradermica di acido ialuronico

Barsotti G.
Ultimo
2021-01-01

Abstract

Introduction and aim of the study: to report the clinical outcome of trichiasis treatment by intradermal injections of 2,4 % hyaluronic acid in dogs and cats. Materials and methods: retrospective study on dogs and cats affected by eyelid trichiasis treated with intradermal injection of 2.4% hyaluronic acid. The procedure was used as an alternative to conventional surgery because of severe concomitant systemic diseases or refusal to general anesthesia by the owners. Mild sedation was needed only in aggressive or restless animals. Application of a topical anesthetic cream to the eyelid skin was performed on non-sedated animals. Hyaluronic acid was injected in a volume sufficient to obtain the disappearance of trichiasis (maximum volume 0.6 ml). Results: twenty-three animals (4 cats and 19 dogs) were treated, for a total of 34 eyes. No systemic adverse reactions were observed as consequences of the treatment. All subjects showed locally mild hyperemia, edema and ecchymosis. At the short-term follow-up (30 days post-treatment) 22/23 animals showed complete remission of trichiasis and associated symptoms. Recurrence of trichiasis was observed in 3/13 cases in which a follow-up of more than 6 months was available. Discussion: intradermal injection of hyaluronic acid represents a possible non-invasive therapeutic alternative to conventional surgical resolution of trichiasis, especially in animal patients with high anesthesiologic risk. However, the procedure cannot be considered a definitive treatment because trichiasis could recur at the reabsorption of filler, particularly in cats.
2021
Mezzadri, V.; Crotti, A.; Nardi, S.; Barsotti, G.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/1140844
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