Background The aim of this study was to compare the 2-year outcomes of de novo versus postendovascular lesion treatment of femoropopliteal occlusions included in a national, multicenter, observational, prospective registry based on the treatment of critical Limb-threatening IschaeMia with infragenicular Bypass adopting in situ SAphenous VEin technique (LIMBSAVE) registry. Methods From January 2018 to December 2019, 541 patients from 43 centers have been enrolled in the LIMBSAVE registry. Of these patients, 460 were included in the present study: 341 (74.1%) with de novo lesions (DN group) and 119 (25.9%) with postendovascular treatment lesions (PE group). Initial outcome measures were assessed at 30 days after treatment. Furthermore, at the 2-year follow-up, the estimated outcomes of primary patency, primary-assisted patency, secondary patency, and limb salvage were analyzed with Kaplan-Meier curves and compared between groups with the log-rank test. Results Both groups were homogeneous in terms of demographic data, preoperative risk factors, and clinical presentation. However, compared with DN group, more patients in PE group had a great saphenous vein diameter of less than 3 mm (11.1% vs 21%; P = .007). Intraoperatively, both groups showed similar distal anastomosis sites: below-the-knee popliteal artery (63% DN group, 66.4% PE group) and tibial vessel (37% DN group, 33.6% PE group) (P = .3). The overall mean duration of follow-up was 11.6 months (range, 1-24 months). At the 2-year follow-up, there were no differences between the two groups in terms of primary patency (66.3% DN group vs 74.1% PE group; P = .9), primary-assisted patency (78.2% DN group vs 79.5% PE group; P = .2), secondary patency (85.1% DN group vs 91.4% PE group; P = .2), and limb salvage (95.2% DN group vs 95.1% PE group; P = .9). Conclusions The LIMBSAVE registry did not show a worsening of overall patency and limb salvages rates at the 2-year follow-up in patients undergoing in situ saphenous bypass after a failed endovascular approach for long femoropopliteal occlusive disease. This finding is in contrast with what has been published in literature.

Comparison of long occlusive femoropopliteal de novo versus previous endovascularly treated lesions managed with in situ saphenous bypass

Troisi, Nicola
Primo
Writing – Original Draft Preparation
;
Berchiolli, Raffaella
Ultimo
Writing – Review & Editing
;
Ferrari, Mauro
Membro del Collaboration Group
;
2022-01-01

Abstract

Background The aim of this study was to compare the 2-year outcomes of de novo versus postendovascular lesion treatment of femoropopliteal occlusions included in a national, multicenter, observational, prospective registry based on the treatment of critical Limb-threatening IschaeMia with infragenicular Bypass adopting in situ SAphenous VEin technique (LIMBSAVE) registry. Methods From January 2018 to December 2019, 541 patients from 43 centers have been enrolled in the LIMBSAVE registry. Of these patients, 460 were included in the present study: 341 (74.1%) with de novo lesions (DN group) and 119 (25.9%) with postendovascular treatment lesions (PE group). Initial outcome measures were assessed at 30 days after treatment. Furthermore, at the 2-year follow-up, the estimated outcomes of primary patency, primary-assisted patency, secondary patency, and limb salvage were analyzed with Kaplan-Meier curves and compared between groups with the log-rank test. Results Both groups were homogeneous in terms of demographic data, preoperative risk factors, and clinical presentation. However, compared with DN group, more patients in PE group had a great saphenous vein diameter of less than 3 mm (11.1% vs 21%; P = .007). Intraoperatively, both groups showed similar distal anastomosis sites: below-the-knee popliteal artery (63% DN group, 66.4% PE group) and tibial vessel (37% DN group, 33.6% PE group) (P = .3). The overall mean duration of follow-up was 11.6 months (range, 1-24 months). At the 2-year follow-up, there were no differences between the two groups in terms of primary patency (66.3% DN group vs 74.1% PE group; P = .9), primary-assisted patency (78.2% DN group vs 79.5% PE group; P = .2), secondary patency (85.1% DN group vs 91.4% PE group; P = .2), and limb salvage (95.2% DN group vs 95.1% PE group; P = .9). Conclusions The LIMBSAVE registry did not show a worsening of overall patency and limb salvages rates at the 2-year follow-up in patients undergoing in situ saphenous bypass after a failed endovascular approach for long femoropopliteal occlusive disease. This finding is in contrast with what has been published in literature.
2022
Troisi, Nicola; Michelagnoli, Stefano; Adami, Daniele; Berchiolli, Raffaella; Accrocca, Federico; Amico, Alessio; Angelini, Andrea; Arnuzzo, Luca; Marchetti, Andrea Ascoli; Attisani, Luca; Bafile, Gennaro; Baldino, Giuseppe; Barbanti, Enrico; Bartoli, Stefano; Bellosta, Raffaello; Benedetto, Filippo; Borioni, Raoul; Briolini, Franco; Busoni, Cristina; Camparini, Stefano; Cappiello, Pierluigi; Carbonari, Luciano; Casella, Francesco; Celoria, Giovanni; Chiama, Andrea; Chisci, Emiliano; Civilini, Efrem; Codispoti, Francesco; Conti, Barbara; Coppi, Giovanni; De Blasis, Giovanni; D’Elia, Marcello; Di Domenico, Rossella; Di Girolamo, Carla; Ercolini, Leonardo; Ferrari, Alessandra; Ferrari, Mauro; Forliti, Enzo; Frigatti, Paolo; Frigerio, Dalmazio; Frosini, Pierfrancesco; Garriboli, Luca; Giordano, Antonio Nicola; Guerrieri, Walter; Jannello, Antonio; Massara, Mafalda; Merlo, Maurizio; Mezzetti, Roberto; Miccoli, Tommaso; Milite, Domenico; Mingazzini, Pietro; Muncinelli, Marina; Nano, Giovanni; Natola, Marco; Novali, Claudio; Palasciano, Giancarlo; Perkmann, Reinhold; Persi, Federica; Petruccelli, David; Pinelli, Mauro; Poletto, Giorgio; Porta, Carla; Pratesi, Carlo; Pruner, Gianguido; Ragazzi, Giovanni; Righini, Paolo; Salvini, Mauro; Scovazzi, Paolo; Setacci, Carlo; Settembrini, Alberto Maria; Siani, Andrea; Silingardi, Roberto; Silvestro, Antonino; Talarico, Francesco; Tolva, Valerio; Trani, Antonio; Trimarchi, Santi; Tshomba, Yamume; Vigliotti, Gennaro; Viola, Daniela; Volpe, Pietro; Zani, Federico
File in questo prodotto:
File Dimensione Formato  
1-s2.0-S0741521422015002-main.pdf

solo utenti autorizzati

Licenza: NON PUBBLICO - accesso privato/ristretto
Dimensione 600.65 kB
Formato Adobe PDF
600.65 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/1143104
Citazioni
  • ???jsp.display-item.citation.pmc??? 0
  • Scopus 2
  • ???jsp.display-item.citation.isi??? 1
social impact