1. An annuloplasty device comprising: an annuloplasty ring comprising a first end and a second end opposite the first end, the annuloplasty ring configured to transition between an elongate insertion geometry and an annular operable geometry; a plurality of anchors disposed within the annuloplasty ring, the plurality of anchors configured to assume a deployment configuration when the annuloplasty ring is in the annular operable geometry; and at least one synthetic leaflet in mechanical communication with the annuloplasty ring at a plurality of points. 2. The annuloplasty device of claim 1, wherein the at least one synthetic leaflet comprises: a valve frame comprising a proximal opening; and a synthetic leaflet material mechanically coupled to the valve frame, wherein the synthetic leaflet material is disposed within the proximal opening. 3. The annuloplasty device of claim 2, wherein the valve frame comprises a shape memory metal. 4. The annuloplasty device of claim 2, wherein the synthetic leaflet material comprises a polymeric material. 5. The annuloplasty device of claim 1, wherein the at least one synthetic leaflet comprises a plurality of leaflets. 6. The annuloplasty device of claim 5, wherein the plurality of leaflets comprise: a first leaflet positioned adjacent to the first end of the annuloplasty ring; and a second leaflet positioned adjacent to the second end of the annuloplasty ring. 7. The annuloplasty device of claim 6, wherein at least a portion of each of the first leaflet and the second leaflet are mechanically coupled. 8. The annuloplasty device of claim 1, wherein the at least one synthetic leaflet is in mechanical communication with the annuloplasty ring at a plurality of points on a posterior side of a native valve. 9. The annuloplasty device of claim 1, wherein the at least one synthetic leaflets is in mechanical communication with the annuloplasty ring at a plurality of points on an anterior side of the native valve. 10. The annuloplasty device of claim 1, wherein the annuloplasty ring further comprises a plurality of anchor windows through which the plurality of anchors are deployable. 11. The annuloplasty device of claim 1, wherein the annuloplasty ring comprises a coating. 12. The annuloplasty device of claim 11, wherein the coating comprises a polyethylene terephthalate coating. 13. The annuloplasty device of claim 1, wherein the annuloplasty ring comprises a shape memory metal. 14. The annuloplasty device of claim 1, wherein the at least one synthetic leaflet comprises one or more lace holes configured to receive a suture therethrough. 15. The annuloplasty device of claim 1, wherein the annuloplasty ring further comprises at least one snap mechanism configured to connect the first end and the second end. 16. An anchor device, comprising: a leaflet anchor comprising an anchor body comprising a first end and a second end; an anchor portion in mechanical communication with the first end of the leaflet anchor; a separating element in mechanical communication with the second end of the leaflet anchor; and a disk portion in mechanical communication with the anchor body between the first end and the second end. 17. The anchor device of claim 16, wherein the anchor portion comprises a shape memory metal. 18. The anchor device of claim 16, wherein the anchor body comprises a shape memory metal. 19. The anchor device of claim 16, wherein the separating element is configured to rotate the anchor body. 20. A method of implanting an annuloplasty device within a patient, the method comprising: delivering, into the patient, an annuloplasty ring in an elongate insertion geometry, the annuloplasty ring comprising at least one synthetic leaflet in mechanical communication with an annuloplasty ring at a plurality of points; and positioning the annuloplasty ring parallel to a plane of a valve annulus of the patient. 21. The method of claim 20, wherein the annuloplasty ring is delivered using one of a trans-apical approach, a trans-septal approach, a trans-femoral approach, a trans-jugular approach, or a trans-atrial approach.

ANNULOPLASTY RING WITH POSTERIOR LEAFLET FOR MINIMALLY INVASIVE TREATMENT

Colli;
2020-01-01

Abstract

1. An annuloplasty device comprising: an annuloplasty ring comprising a first end and a second end opposite the first end, the annuloplasty ring configured to transition between an elongate insertion geometry and an annular operable geometry; a plurality of anchors disposed within the annuloplasty ring, the plurality of anchors configured to assume a deployment configuration when the annuloplasty ring is in the annular operable geometry; and at least one synthetic leaflet in mechanical communication with the annuloplasty ring at a plurality of points. 2. The annuloplasty device of claim 1, wherein the at least one synthetic leaflet comprises: a valve frame comprising a proximal opening; and a synthetic leaflet material mechanically coupled to the valve frame, wherein the synthetic leaflet material is disposed within the proximal opening. 3. The annuloplasty device of claim 2, wherein the valve frame comprises a shape memory metal. 4. The annuloplasty device of claim 2, wherein the synthetic leaflet material comprises a polymeric material. 5. The annuloplasty device of claim 1, wherein the at least one synthetic leaflet comprises a plurality of leaflets. 6. The annuloplasty device of claim 5, wherein the plurality of leaflets comprise: a first leaflet positioned adjacent to the first end of the annuloplasty ring; and a second leaflet positioned adjacent to the second end of the annuloplasty ring. 7. The annuloplasty device of claim 6, wherein at least a portion of each of the first leaflet and the second leaflet are mechanically coupled. 8. The annuloplasty device of claim 1, wherein the at least one synthetic leaflet is in mechanical communication with the annuloplasty ring at a plurality of points on a posterior side of a native valve. 9. The annuloplasty device of claim 1, wherein the at least one synthetic leaflets is in mechanical communication with the annuloplasty ring at a plurality of points on an anterior side of the native valve. 10. The annuloplasty device of claim 1, wherein the annuloplasty ring further comprises a plurality of anchor windows through which the plurality of anchors are deployable. 11. The annuloplasty device of claim 1, wherein the annuloplasty ring comprises a coating. 12. The annuloplasty device of claim 11, wherein the coating comprises a polyethylene terephthalate coating. 13. The annuloplasty device of claim 1, wherein the annuloplasty ring comprises a shape memory metal. 14. The annuloplasty device of claim 1, wherein the at least one synthetic leaflet comprises one or more lace holes configured to receive a suture therethrough. 15. The annuloplasty device of claim 1, wherein the annuloplasty ring further comprises at least one snap mechanism configured to connect the first end and the second end. 16. An anchor device, comprising: a leaflet anchor comprising an anchor body comprising a first end and a second end; an anchor portion in mechanical communication with the first end of the leaflet anchor; a separating element in mechanical communication with the second end of the leaflet anchor; and a disk portion in mechanical communication with the anchor body between the first end and the second end. 17. The anchor device of claim 16, wherein the anchor portion comprises a shape memory metal. 18. The anchor device of claim 16, wherein the anchor body comprises a shape memory metal. 19. The anchor device of claim 16, wherein the separating element is configured to rotate the anchor body. 20. A method of implanting an annuloplasty device within a patient, the method comprising: delivering, into the patient, an annuloplasty ring in an elongate insertion geometry, the annuloplasty ring comprising at least one synthetic leaflet in mechanical communication with an annuloplasty ring at a plurality of points; and positioning the annuloplasty ring parallel to a plane of a valve annulus of the patient. 21. The method of claim 20, wherein the annuloplasty ring is delivered using one of a trans-apical approach, a trans-septal approach, a trans-femoral approach, a trans-jugular approach, or a trans-atrial approach.
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/1151109
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact