We report on the treatment with micafungin of a pacemaker-associated endocarditis due to Candida albicans. Antifungal therapy was able to reduce vegetation size from 5 to 1 cm making possible the transvenous removal of the device without a high risk of pulmonary embolism. Noteworthy, a high micafungin concentration was documented into the lead vegetation (10 mu g/g of vegetation tissue) and this may have contributed to the striking size reduction of vegetation.
Micafungin for Candida albicans pacemaker-associated endocarditis: a case report and review of the literature
Bongiorni, Maria Grazia
Primo
;Tagliaferri, Enrico;Di Paolo, Antonello;Di Cori, Andrea;
2013-01-01
Abstract
We report on the treatment with micafungin of a pacemaker-associated endocarditis due to Candida albicans. Antifungal therapy was able to reduce vegetation size from 5 to 1 cm making possible the transvenous removal of the device without a high risk of pulmonary embolism. Noteworthy, a high micafungin concentration was documented into the lead vegetation (10 mu g/g of vegetation tissue) and this may have contributed to the striking size reduction of vegetation.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
