The pharmaceutical industry has increasingly adopted liposomes as a means of drug delivery thanks to their biocompatibility and suitability for both hydrophilic and hydrophobic substrates. A number of factors, such as average diameter, size distribution, and lamellarity (number of bilayers), play a crucial role in determining the drug release profile, and existing batch production methods do not offer the level of control needed for fine-tuning of parameters. More recently, microfluidics has established itself as a desirable alternative, offering consistent particle diameters, narrow size distribution, and good batch-to-batch reproducibility

Channelling the future of liposome generation

Damiano Rossi;
2019-01-01

Abstract

The pharmaceutical industry has increasingly adopted liposomes as a means of drug delivery thanks to their biocompatibility and suitability for both hydrophilic and hydrophobic substrates. A number of factors, such as average diameter, size distribution, and lamellarity (number of bilayers), play a crucial role in determining the drug release profile, and existing batch production methods do not offer the level of control needed for fine-tuning of parameters. More recently, microfluidics has established itself as a desirable alternative, offering consistent particle diameters, narrow size distribution, and good batch-to-batch reproducibility
2019
Rossi, Damiano; Blakney, Anna
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/1165229
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