Aurones: Golden resource for active compounds

Deemed as poorly represented in nature, aurones have been often overlooked by researchers compared to other members of the flavonoid superfamily. However, over the past two decades, Abstract: Deemed as poorly represented in nature, aurones have been often overlooked by researchers compared to other members of the flavonoid superfamily. However, over the past two decades, they they have been reassessed by the scientific community, who are increasingly appreciating their ability to modulate several biological pathways. This review summarizes the recent literature on this have been reassessed by the scientific community, who are increasingly appreciating their ability to modulate several biological pathways. This review summarizes the recent literature on this class of class of compounds, which has been analyzed from both a chemical and a functional point of view. compounds, which has been analyzed from both a chemical and a functional point of view. Original Original articles, reviews and editorials featured in Pubmed and Scifinder over the last twenty years articles, reviews and editorials featured in Pubmed and Scifinder over the last twenty years have been have been taken into account to provide the readers with a view of the chemical strategies to obtain taken into account to provide the readers with a view of the chemical strategies to obtain them, their them, their functional properties, and their potential of technological use. The resulting comprehensive picture aims at raising the awareness of these natural derivatives as effective drug candidates, functional properties, and their potential of technological use. The resulting comprehensive picture aims at raising the awareness of these natural derivatives as effective drug candidates, fostering the fostering the development of novel synthetic analogues. development of novel synthetic analogues.