The authors describe the data of an ethnobotanical research concerning the province of La Spezia, in Eastern Liguria. The identified entities, used as medicinal plants, are 53. Calendula arvensis wasn’t known in popular medicine of Liguria; others plants were known with different uses. Finally some unusual medicinal uses have been found for Cynodon dactylon, Mentha longifolia, Pinus halepensis, Ruta graveolens
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