The 'no-reflow phenomenon is still an unsolved issue in the setting of primary revascularization in acute myocardial infarction, and is associated with increased mortality, increased infarct size and left ventricular remodeling. A specific approach to this problem includes prevention of atherothrombotic debris dislocation by the use of embolic protection and thrombectomy devices. We review the literature on the prevention of embolization during primary percutaneous coronary intervention, with both distal protection and thrombus aspiration devices. In particular, this review is focused on rheolytic thrombectomy, and includes published studies and ongoing trials. The available evidence of an improved outcome in selected high-risk patients warrants an adequately designed and powered randomized trial. © 2010 Future Medicine Ltd.
Rheolytic thrombectomy: Any role left?
Petronio A. S.;De Carlo M.Ultimo
2010-01-01
Abstract
The 'no-reflow phenomenon is still an unsolved issue in the setting of primary revascularization in acute myocardial infarction, and is associated with increased mortality, increased infarct size and left ventricular remodeling. A specific approach to this problem includes prevention of atherothrombotic debris dislocation by the use of embolic protection and thrombectomy devices. We review the literature on the prevention of embolization during primary percutaneous coronary intervention, with both distal protection and thrombus aspiration devices. In particular, this review is focused on rheolytic thrombectomy, and includes published studies and ongoing trials. The available evidence of an improved outcome in selected high-risk patients warrants an adequately designed and powered randomized trial. © 2010 Future Medicine Ltd.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
