This study examines the feasibility of reconstructing the spatial dose distribution delivered by a 9 MeV electron beam within a plastic scintillator block using optical tomography. The system is designed for use in 3Ddosimetry for clinical applications in quality assurance and beam characterization, especially with FLASH-beam sources. The proposed detector reconstructs the 3D dose distribution map employing a monolith with 10 cm side, imaged in four different projections by scientific cameras. The 3D dose distribution simulated with Geant4 was reconstructed using a maximum likelihood expectation maximization algorithm applied to the lateral projection, resulting in a longitudinal image with a standard deviation of 0.2 Gy. Furthermore, a preliminary experimental test has been performed.
A 3D imaging system for dosimetry in FLASH radiotherapy
Eleonora Ravera;Rebecca Anzalone;Andrea Cavalieri;Esther Ciarrocchi;Damiano Del Sarto;Fabio Di Martino;Matteo Morrocchi;Maria Giuseppina Bisogni
2024-01-01
Abstract
This study examines the feasibility of reconstructing the spatial dose distribution delivered by a 9 MeV electron beam within a plastic scintillator block using optical tomography. The system is designed for use in 3Ddosimetry for clinical applications in quality assurance and beam characterization, especially with FLASH-beam sources. The proposed detector reconstructs the 3D dose distribution map employing a monolith with 10 cm side, imaged in four different projections by scientific cameras. The 3D dose distribution simulated with Geant4 was reconstructed using a maximum likelihood expectation maximization algorithm applied to the lateral projection, resulting in a longitudinal image with a standard deviation of 0.2 Gy. Furthermore, a preliminary experimental test has been performed.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.