This study examines the feasibility of reconstructing the spatial dose distribution delivered by a 9 MeV electron beam within a plastic scintillator block using optical tomography. The system is designed for use in 3Ddosimetry for clinical applications in quality assurance and beam characterization, especially with FLASH-beam sources. The proposed detector reconstructs the 3D dose distribution map employing a monolith with 10 cm side, imaged in four different projections by scientific cameras. The 3D dose distribution simulated with Geant4 was reconstructed using a maximum likelihood expectation maximization algorithm applied to the lateral projection, resulting in a longitudinal image with a standard deviation of 0.2 Gy. Furthermore, a preliminary experimental test has been performed.

A 3D imaging system for dosimetry in FLASH radiotherapy

Eleonora Ravera;Rebecca Anzalone;Andrea Cavalieri;Esther Ciarrocchi;Damiano Del Sarto;Fabio Di Martino;Matteo Morrocchi;Maria Giuseppina Bisogni
2024-01-01

Abstract

This study examines the feasibility of reconstructing the spatial dose distribution delivered by a 9 MeV electron beam within a plastic scintillator block using optical tomography. The system is designed for use in 3Ddosimetry for clinical applications in quality assurance and beam characterization, especially with FLASH-beam sources. The proposed detector reconstructs the 3D dose distribution map employing a monolith with 10 cm side, imaged in four different projections by scientific cameras. The 3D dose distribution simulated with Geant4 was reconstructed using a maximum likelihood expectation maximization algorithm applied to the lateral projection, resulting in a longitudinal image with a standard deviation of 0.2 Gy. Furthermore, a preliminary experimental test has been performed.
2024
Ravera, Eleonora; Anzalone, Rebecca; Cavalieri, Andrea; Ciarrocchi, Esther; DEL SARTO, Damiano; DI MARTINO, Fabio; Morrocchi, Matteo; Bisogni, MARIA G...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/1275469
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