Although calcium antagonists are drugs which have been introduced relatively recently, their use is already so widespread, at least in the treatment of cardiovascular diseases as to represent one of the main therapies for diseases such as ischaemic cardiopathy, arterial hypertension, and, to a lesser extent, arrhythmias. Together with the development of clinical applications, deeper insight has been gained into the clinical and experimental pharmacology of these drugs. The authors of this review concentrate their attention on some of the less frequently discussed aspects of calcium antagonists. On the one hand, they describe some "nonprimary" uses of these drugs, both in the cardiovascular and in other therapeutic fields, which already receive confirmation from relatively solid experimental data. On the other hand, they review the side effects and some pharmacological interactions of calcium antagonists, both of which should be held in due consideration, seeing that these drugs are widely employed in clinical practice and their use often requires prolonged, intensive treatment. The most common side effects are described, together with others relatively less well known ones, and outline is given of potential undesirable effects on the cardiovascular as well as on other systems.

Calcium antagonists: accounts on new perspectives of their use and an update on side effects

PALOMBO, CARLO;
1989

Abstract

Although calcium antagonists are drugs which have been introduced relatively recently, their use is already so widespread, at least in the treatment of cardiovascular diseases as to represent one of the main therapies for diseases such as ischaemic cardiopathy, arterial hypertension, and, to a lesser extent, arrhythmias. Together with the development of clinical applications, deeper insight has been gained into the clinical and experimental pharmacology of these drugs. The authors of this review concentrate their attention on some of the less frequently discussed aspects of calcium antagonists. On the one hand, they describe some "nonprimary" uses of these drugs, both in the cardiovascular and in other therapeutic fields, which already receive confirmation from relatively solid experimental data. On the other hand, they review the side effects and some pharmacological interactions of calcium antagonists, both of which should be held in due consideration, seeing that these drugs are widely employed in clinical practice and their use often requires prolonged, intensive treatment. The most common side effects are described, together with others relatively less well known ones, and outline is given of potential undesirable effects on the cardiovascular as well as on other systems.
Palombo, Carlo; Mian, M; Bertelli, A.
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/12846
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact