Anti-inflammatory properties may contribute to the pharmacological effects of angiotensin II receptor blockers (ARBs), a leading therapeutic class in the management of hypertension and related cardiovascular and renal diseases. That possibility, supported by consistent evidence from in-vitro and animal studies showing pro-inflammatory properties of angiotensin II, has been evaluated clinically by measuring the effect of ARBs on C-reactive protein and other circulating indices of inflammation (e-selectin, adhesion molecules, interleukin-6, tissue necrosis factor-alpha, monocyte chemoattractant protein-1) of potential clinical relevance, a body of evidence that this paper aims to review.
|Autori:||DEL FIORENTINO A; CIANCHETTI S; CELI A; DELLOMO G; PEDRINELLI R|
|Titolo:||The effect of angiotensin receptor blockers on C reactive protein and other circulating inflammatory indices|
|Anno del prodotto:||2009|
|Appare nelle tipologie:||1.1 Articolo in rivista|