The aim of this work was to evaluate the phytohaemagglutinin-induced aggregation of circulating neutrophils isolated from 25 patients affected by chronic myeloproliferative syndromes (polycythaemia vera, chronic myeloid leukaemia in chronic phase, and essential thrombocythaemia). The results showed a lesser aggregating capacity in chronic myeloid leukaemia (CML) and an opposite behaviour in polycythaemia vera and essential thrombocythaemia. Patients with polycythaemia vera whose neutrophils showed a greater aggregating capacity were shown to have had various vascular complications.

Phytohaemagglutinin-induced neutrophil aggregation in patients affected by chronic myeloproliferative diseases.

CARULLI, GIOVANNI;VAGLINI, FRANCESCA;
1990

Abstract

The aim of this work was to evaluate the phytohaemagglutinin-induced aggregation of circulating neutrophils isolated from 25 patients affected by chronic myeloproliferative syndromes (polycythaemia vera, chronic myeloid leukaemia in chronic phase, and essential thrombocythaemia). The results showed a lesser aggregating capacity in chronic myeloid leukaemia (CML) and an opposite behaviour in polycythaemia vera and essential thrombocythaemia. Patients with polycythaemia vera whose neutrophils showed a greater aggregating capacity were shown to have had various vascular complications.
Carulli, Giovanni; Baicchi, U; Marini, A; Vaglini, Francesca; Grassi, B; Ambrogi, F.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11568/13229
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