OBJECTIVES: Benign tracheal stenosis, as a complication of intubation or tracheotomy, is a rare but life-threatening condition. Surgical resection with end-to-end anastomosis is considered the standard treatment, when possible, providing satisfactory results in over 90% of cases. However, limited research has focused on assessing the subjective perception of quality of life (QoL) following this surgical intervention. METHODS: This study involved patients who underwent surgical treatment for tracheal stenosis at the Thoracic Surgery Unit of Pisa over a 10-year period, including 12 patients treated after March 2020 during the peak of the Covid-19 pandemic. A dedicated mixed-method questionnaire was administered to evaluate short-term perceived QoL across three domains: general functionality, organ-specific functionality and psychological well-being. The assessment was performed both before surgery (PRE-period) and 3 months after surgery (POST-period). RESULTS: The study included 22 patients and found a significant overall improvement in QoL following surgery, with a mean total score reduction of −14.64 (95% CI: −18.45 to 10.90, P < 0.001). General functionality and psychological well-being scores improved notably, with POST-PRE differences of −7.59 (95% CI: −9.22 to 5.68, P = 0.015) and −3.18 (95% CI: −4.22 to 1.91; P = 0.046), respectively. Patients with a history of Covid-19 showed greater improvements in general functionality (P = 0.042) and psychological well-being (P = 0.043) than others. CONCLUSIONS: Surgical intervention for tracheal stenosis significantly enhances perceived patients’ QoL, particularly in general functionality and psychological well-being areas. The results indicate that patients with a history of Covid-19 may experience a more pronounced recovery. Despite the risk of early postoperative complications, the overall improvement in QoL supports the effectiveness of surgical treatment.

Short-term perceived quality of life after surgical resection for benign tracheal stenosis: a pre-post intervention study

Aprile V.
;
Bacchin D.;Lenzini A.;Korasidis S.;Gabriele S.;Ribechini A.;Milazzo M.;Ambrogi M. C.;Lucchi M.
2025-01-01

Abstract

OBJECTIVES: Benign tracheal stenosis, as a complication of intubation or tracheotomy, is a rare but life-threatening condition. Surgical resection with end-to-end anastomosis is considered the standard treatment, when possible, providing satisfactory results in over 90% of cases. However, limited research has focused on assessing the subjective perception of quality of life (QoL) following this surgical intervention. METHODS: This study involved patients who underwent surgical treatment for tracheal stenosis at the Thoracic Surgery Unit of Pisa over a 10-year period, including 12 patients treated after March 2020 during the peak of the Covid-19 pandemic. A dedicated mixed-method questionnaire was administered to evaluate short-term perceived QoL across three domains: general functionality, organ-specific functionality and psychological well-being. The assessment was performed both before surgery (PRE-period) and 3 months after surgery (POST-period). RESULTS: The study included 22 patients and found a significant overall improvement in QoL following surgery, with a mean total score reduction of −14.64 (95% CI: −18.45 to 10.90, P < 0.001). General functionality and psychological well-being scores improved notably, with POST-PRE differences of −7.59 (95% CI: −9.22 to 5.68, P = 0.015) and −3.18 (95% CI: −4.22 to 1.91; P = 0.046), respectively. Patients with a history of Covid-19 showed greater improvements in general functionality (P = 0.042) and psychological well-being (P = 0.043) than others. CONCLUSIONS: Surgical intervention for tracheal stenosis significantly enhances perceived patients’ QoL, particularly in general functionality and psychological well-being areas. The results indicate that patients with a history of Covid-19 may experience a more pronounced recovery. Despite the risk of early postoperative complications, the overall improvement in QoL supports the effectiveness of surgical treatment.
2025
Aprile, V.; Bacchin, D.; Lenzini, A.; Mastromarino, M. G.; Korasidis, S.; Gabriele, S.; Ribechini, A.; Milazzo, M.; Ambrogi, M. C.; Lucchi, M....espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/1343027
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