The angiogenic process is complex and characterized by the formation of capillary blood vessels in physiological and pathological conditions such as tumors. In this chapter, we provide a brief introduction to the book about the history of angiogenesis and its state-of-the-art overview, with a focus on the discoveries of the past 20 years, including lymphangiogenesis. After an introductory section dealing with historical notes and pioneer approaches, recent concepts and innovative pro- and antiangiogenic therapeutic strategies are reported and commented. Furthermore, a particular attention is paid to the different types of the process, as well as to experimental models. © 2026 Elsevier Inc. All rights reserved
Introduction
Gianfranco Natale;Guido Bocci
2026-01-01
Abstract
The angiogenic process is complex and characterized by the formation of capillary blood vessels in physiological and pathological conditions such as tumors. In this chapter, we provide a brief introduction to the book about the history of angiogenesis and its state-of-the-art overview, with a focus on the discoveries of the past 20 years, including lymphangiogenesis. After an introductory section dealing with historical notes and pioneer approaches, recent concepts and innovative pro- and antiangiogenic therapeutic strategies are reported and commented. Furthermore, a particular attention is paid to the different types of the process, as well as to experimental models. © 2026 Elsevier Inc. All rights reservedI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
