DNA-templated copper nanoclusters are such versatile nanomaterials that have attracted much attention in recent years due to their outstanding properties including versatility in various label-free chemical and biological assays and sensing mechanisms, low price, low toxicity, good biocompatibility, and Mega-Stokes shifts. However, the design of new sensing strategies for any analytes requires a comprehensive understanding of the already proposed assays. With this goal in mind, a systematic review of their properties, synthesis and applications in sensing is required. For this reason, an in-depth survey of the recent progress achieved by the most prominent works is provided here to address both the advantages and limitations of DNA-CuNCs in chemical and biological sensing and analysis. Future outlooks on potential developments and current challenges are also provided.

Synthesis, properties and applications of DNA-templated copper nanoclusters in chemical and biological sensing

Fabio Spiaggia
Primo
;
Maria Minunni
Ultimo
2025-01-01

Abstract

DNA-templated copper nanoclusters are such versatile nanomaterials that have attracted much attention in recent years due to their outstanding properties including versatility in various label-free chemical and biological assays and sensing mechanisms, low price, low toxicity, good biocompatibility, and Mega-Stokes shifts. However, the design of new sensing strategies for any analytes requires a comprehensive understanding of the already proposed assays. With this goal in mind, a systematic review of their properties, synthesis and applications in sensing is required. For this reason, an in-depth survey of the recent progress achieved by the most prominent works is provided here to address both the advantages and limitations of DNA-CuNCs in chemical and biological sensing and analysis. Future outlooks on potential developments and current challenges are also provided.
2025
Spiaggia, Fabio; Palladino, Pasquale; Ravelet, Corinne; Minunni, Maria
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11568/1356870
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