Objective To determine the concentrations of zearalenone and its metabolites in the leading brands of infant formula milks and meat-based infant foods commonly marketed in Italy, and to assess their repercussion in the provisional tolerable daily intakes of these estrogenic mycotoxins. Study design A total of 185 cow's milk-based infant formulas and 44 samples of meat-based infant foods samples were analyzed. The analysis of mycotoxins was performed by immunoaffinity column clean-up and high-pressure liquid chromatography with fluorescence detection. Results Zearalenone was detected in 17 (9%) milk samples (maximum 0.76 mu g/L). The alpha-zearalenol was detected in 49 (26%) milk samples (maximum 12.91 mu g/L). The beta-zearalenol was detected in 53 (28%) milk samples (maximum 73.24 mu g/L). The alpha-zearalanol and beta-zearalanol were not detected in milk samples. Although a-zearalenol was detected in 12 (27%) meat samples (maximum 30.50 mu g/kg), only one meat-based sample was contaminated by alpha-zearalanol (950 mu g/kg). Zearalenone, beta-zearalenol, and beta-zearalanol were not detected in meat samples. Conclusions This study shows the presence of mycoestrogens in infant (milk-based and meat-based) food, and this is likely to have great implications for subsequent generations, suggesting the need to perform occurrence surveys in this type of food. (J Pediatr 2011; 159: 278-83).

Mycoestrogen Pollution of Italian Infant Food

MEUCCI, VALENTINA;SOLDANI, GIULIO;SAGGESE, GIUSEPPE;
2011

Abstract

Objective To determine the concentrations of zearalenone and its metabolites in the leading brands of infant formula milks and meat-based infant foods commonly marketed in Italy, and to assess their repercussion in the provisional tolerable daily intakes of these estrogenic mycotoxins. Study design A total of 185 cow's milk-based infant formulas and 44 samples of meat-based infant foods samples were analyzed. The analysis of mycotoxins was performed by immunoaffinity column clean-up and high-pressure liquid chromatography with fluorescence detection. Results Zearalenone was detected in 17 (9%) milk samples (maximum 0.76 mu g/L). The alpha-zearalenol was detected in 49 (26%) milk samples (maximum 12.91 mu g/L). The beta-zearalenol was detected in 53 (28%) milk samples (maximum 73.24 mu g/L). The alpha-zearalanol and beta-zearalanol were not detected in milk samples. Although a-zearalenol was detected in 12 (27%) meat samples (maximum 30.50 mu g/kg), only one meat-based sample was contaminated by alpha-zearalanol (950 mu g/kg). Zearalenone, beta-zearalenol, and beta-zearalanol were not detected in meat samples. Conclusions This study shows the presence of mycoestrogens in infant (milk-based and meat-based) food, and this is likely to have great implications for subsequent generations, suggesting the need to perform occurrence surveys in this type of food. (J Pediatr 2011; 159: 278-83).
Meucci, Valentina; Soldani, Giulio; Razzuoli, E; Saggese, Giuseppe; Massart, F.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11568/146665
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