Objective To determine the concentrations of zearalenone and its metabolites in the leading brands of infant formula milks and meat-based infant foods commonly marketed in Italy, and to assess their repercussion in the provisional tolerable daily intakes of these estrogenic mycotoxins. Study design A total of 185 cow's milk-based infant formulas and 44 samples of meat-based infant foods samples were analyzed. The analysis of mycotoxins was performed by immunoaffinity column clean-up and high-pressure liquid chromatography with fluorescence detection. Results Zearalenone was detected in 17 (9%) milk samples (maximum 0.76 mu g/L). The alpha-zearalenol was detected in 49 (26%) milk samples (maximum 12.91 mu g/L). The beta-zearalenol was detected in 53 (28%) milk samples (maximum 73.24 mu g/L). The alpha-zearalanol and beta-zearalanol were not detected in milk samples. Although a-zearalenol was detected in 12 (27%) meat samples (maximum 30.50 mu g/kg), only one meat-based sample was contaminated by alpha-zearalanol (950 mu g/kg). Zearalenone, beta-zearalenol, and beta-zearalanol were not detected in meat samples. Conclusions This study shows the presence of mycoestrogens in infant (milk-based and meat-based) food, and this is likely to have great implications for subsequent generations, suggesting the need to perform occurrence surveys in this type of food. (J Pediatr 2011; 159: 278-83).
|Autori:||MEUCCI V; SOLDANI G; RAZZUOLI E; SAGGESE G; MASSART F|
|Titolo:||Mycoestrogen Pollution of Italian Infant Food|
|Anno del prodotto:||2011|
|Digital Object Identifier (DOI):||10.1016/j.jpeds.2011.01.028|
|Appare nelle tipologie:||1.1 Articolo in rivista|