Radiation exposure leads to an increased risk for cancer and, possibly, additional ill-defined non-cancer risk, including atherosclerotic, cardiovascular, cerebro-vascular and neurodegenerative effects. Studies of brain irradiation in animals and humans provide evidence of apoptosis, neuro-inflammation, loss of oligo-dendrocytes precursors and myelin sheaths, and irreversible damage to the neural stem compartment with long-term impairment of adult neurogenesis. With the present paper we aim to present a comprehensive review on brain effects of radiation exposure, with a special focus on its impact on cognitive processes and psychological functions, as well as on their possible role in the pathophysiology of different psychiatric disorders.
|Autori:||MARAZZITI D; BARONI S; CATENA-DELL'OSSO M; SCHIAVI E; CERESOLI D; CONVERSANO C; DELL'OSSO L; PICANO E.|
|Titolo:||Cognitive, Psychological and Psychiatric Effects of Ionizing Radiation Exposure|
|Anno del prodotto:||2012|
|Appare nelle tipologie:||1.1 Articolo in rivista|